Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Jonathan P, Moorman"'
Autor:
Zhi Q. Yao, Madison B. Schank, Juan Zhao, Mohamed El Gazzar, Ling Wang, Yi Zhang, Addison C. Hill, Puja Banik, Jaeden S. Pyburn, Jonathan P. Moorman
Publikováno v:
Frontiers in Genome Editing, Vol 6 (2024)
Hepatitis B virus (HBV) infection is a common cause of liver disease worldwide. The current antiviral treatment using nucleotide analogues (NAs) can only suppress de novo HBV replication but cannot eliminate chronic HBV infection due to the persisten
Externí odkaz:
https://doaj.org/article/ab3c90e1cef24ca1b1d36dfaa998187a
Autor:
Ling Wang, Juan Zhao, Madison Schank, Addison C. Hill, Puja Banik, Yi Zhang, Xiao Y. Wu, Janet W. Lightner, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
Despite effective control of HIV replication by antiretroviral therapy (ART), a significant number of people living with HIV (PLWH) fail to achieve complete immune reconstitution and thus are deemed immune non-responders (INRs). Compared with immune
Externí odkaz:
https://doaj.org/article/ddb58edf242448ef8caf4bdb5f38788c
Autor:
Anna Musket, Sandra Davern, Brianna M. Elam, Philip R. Musich, Jonathan P. Moorman, Yong Jiang
Publikováno v:
Frontiers in Nuclear Medicine, Vol 3 (2024)
Radionuclide-mediated diagnosis and therapy have emerged as effective and low-risk approaches to treating breast cancer. Compared to traditional anatomic imaging techniques, diagnostic radionuclide-based molecular imaging systems exhibit much greater
Externí odkaz:
https://doaj.org/article/6a89b6d1110c444a87cc1188b8858f1b
Autor:
Xindi Dang, Dechao Cao, Juan Zhao, Madison Schank, Sushant Khanal, Lam Ngoc Thao Nguyen, Xiao Y. Wu, Yi Zhang, Jinyu Zhang, Yong Jiang, Shunbin Ning, Ling Wang, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
T cells are crucial for controlling viral infections; however, the mechanisms that dampen their responses during viral infections remain incompletely understood. Here, we studied the role and mechanisms of mitochondrial topoisomerase 1 (Top1mt) inhib
Externí odkaz:
https://doaj.org/article/948e813200ce459ca33cd08c161976bc
Autor:
Dechao Cao, Sushant Khanal, Ling Wang, Zhengke Li, Juan Zhao, Lam Nhat Nguyen, Lam Ngoc Thao Nguyen, Xindi Dang, Madison Schank, Bal Krishna Chand Thakuri, Jinyu Zhang, Zeyuan Lu, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/f201fe86fcd94344ba8ecb91226cf6e8
Autor:
Ling Wang, Juan Zhao, Lam N. T. Nguyen, James L. Adkins, Madison Schank, Sushant Khanal, Lam N. Nguyen, Xindi Dang, Dechao Cao, Bal Krishna Chand Thakuri, Zeyuan Lu, Jinyu Zhang, Yi Zhang, Xiao Y. Wu, Mohamed El Gazzar, Shunbin Ning, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The recent COVID-19 pandemic poses a serious threat to global public health, thus there is an urgent need to define the molecular mechanisms involved in SARS-CoV-2 spike (S) protein-mediated virus entry that is essential for preventing and/o
Externí odkaz:
https://doaj.org/article/65f0c6e757e64853a3c6e721271fd6cb
Autor:
Madison Schank, Juan Zhao, Ling Wang, Lam Ngoc Thao Nguyen, Yi Zhang, Xiao Y. Wu, Jinyu Zhang, Yong Jiang, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Viruses, Vol 15, Iss 5, p 1061 (2023)
We have previously demonstrated mitochondrial dysfunction in aging CD4 T cells from antiretroviral therapy (ART)-controlled people living with HIV (PLWH). However, the underlying mechanisms by which CD4 T cells develop mitochondrial dysfunction in PL
Externí odkaz:
https://doaj.org/article/99ff10a6770e4f6ba07291c74d1a1e02
Autor:
Bal Krishna Chand Thakuri, Jinyu Zhang, Juan Zhao, Lam N. Nguyen, Lam N. T. Nguyen, Sushant Khanal, Dechao Cao, Xindi Dang, Madison Schank, Xiao Y. Wu, Zheng D. Morrison, Mohamed El Gazzar, Zhengke Li, Yong Jiang, Shunbin Ning, Ling Wang, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) is a long non-coding RNA (lncRNA) that plays a pivotal role in regulating myeloid cell development via targeting HOXA1 gene expression. We and others have previously shown that myel
Externí odkaz:
https://doaj.org/article/a4a3ec38509049228aa48ba468be63bc
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Effectively treating infectious diseases often requires a multi-step approach to target different components involved in disease pathogenesis. Similarly, the COVID-19 pandemic has become a global health crisis that requires a comprehensive understand
Externí odkaz:
https://doaj.org/article/e8ba637fdc454f9599e680f6142436a3
Autor:
Madison Schank, Juan Zhao, Ling Wang, Lam Ngoc Thao Nguyen, Dechao Cao, Xindi Dang, Sushant Khanal, Jinyu Zhang, Yi Zhang, Xiao Y. Wu, Shunbin Ning, Mohamed El Gazzar, Jonathan P. Moorman, Zhi Q. Yao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
We have previously shown that chronic Hepatitis C virus (HCV) infection can induce DNA damage and immune dysfunctions with excessive oxidative stress in T cells. Furthermore, evidence suggests that HCV contributes to increased susceptibility to metab
Externí odkaz:
https://doaj.org/article/6c22ac2c11054b8986dc0390a4c80550