Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jonathan Oliva"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Facioscapulohumeral muscular dystrophy (FSHD) is a degenerative muscle disease caused by loss of epigenetic silencing and ectopic reactivation of the embryonic double homeobox protein 4 gene (DUX4) in skeletal muscle. The p38 MAP kinase inhi
Externí odkaz:
https://doaj.org/article/b095dde51d5a40108b79744a15149e2f
Autor:
Amy E. Campbell, Jonathan Oliva, Matthew P. Yates, Jun Wen Zhong, Sean C. Shadle, Lauren Snider, Nikita Singh, Shannon Tai, Yosuke Hiramuki, Rabi Tawil, Silvère M. van der Maarel, Stephen J. Tapscott, Francis M. Sverdrup
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Background Facioscapulohumeral dystrophy (FSHD) is a progressive muscle disease caused by mutations that lead to epigenetic derepression and inappropriate transcription of the double homeobox 4 (DUX4) gene in skeletal muscle. Drugs that enha
Externí odkaz:
https://doaj.org/article/851f6001f8d54b48828ccacb12eb6194
Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in MiceSummary
Autor:
Barbara Ulmasov, Brent A. Neuschwander-Tetri, Jinping Lai, Vladimir Monastyrskiy, Trisha Bhat, Matthew P. Yates, Jonathan Oliva, Michael J. Prinsen, Peter G. Ruminski, David W. Griggs
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 4, Pp 499-518 (2016)
Background & Aims: Pancreatic stellate cells (PSCs) regulate the development of chronic pancreatitis (CP) and are activated by the cytokine transforming growth factor β (TGFB). Integrins of the αv family promote TGFB signaling in mice, probably
Externí odkaz:
https://doaj.org/article/9a6d1c0077404b55915eba3b895e7df1
Autor:
Ying Yu, Brian R. Bond, Jonathan Oliva, Georg Neckermann, Deena Tajfirouz, Marvin J. Meyers, Mary Campbell, Michael J. Prinsen, Stacy D. Arnett, Robert K. M. Choy, Peter G. Ruminski, Yuhua Ji, Eugenio L. de Hostos, David W. Griggs
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Racecadotril (acetorphan) is a neutral endopeptidase (NEP) inhibitor with known antidiarrheal activity in animals and humans; however, in humans, it suffers from shortcomings that might be improved with newer drugs in this class that have progressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a826f27a9203a5a869599040dc34bad4
http://europepmc.org/articles/PMC4851326
http://europepmc.org/articles/PMC4851326
Autor:
Daniel Natera‐de Benito, Jonathan Olival, Carla Garcia‐Cabau, Cristina Jou, Mònica Roldan, Anna Codina, Jessica Expósito‐Escudero, Cristina Batlle, Laura Carrera‐García, Carlos Ortez, Xavier Salvatella, Francesc Palau, Andrés Nascimento, Janet Hoenicka
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 3, Pp 408-425 (2023)
Abstract Objective Mutations in ANXA11 cause amyotrophic lateral sclerosis (ALS) and have recently been identified as a cause of multisystem proteinopathy and adult‐onset muscular dystrophy. These conditions are adult‐onset diseases and result fr
Externí odkaz:
https://doaj.org/article/078decfbead04403a37de8b0a43ecdd4
Autor:
Christopher S. Eickhoff, Jonathan Oliva, Zhengchao Tu, Daniel E. Goldberg, Xiaorong Liu, David W. Griggs, Megh Singh, Marvin J. Meyers, Francis M. Sverdrup, Limei Qin, Jing Xu, Elizabeth J. Anderson, Michael J. Prinsen, Xiaoping Chen, Wanwan Xu, Peter G. Ruminski, Li Qin, Ke Ding, Stacy D. Arnett, Wentian Zeng, Thomas M. Krenning, Mary Campbell, Siting Zhao, Sarah A. McNitt, Micky D. Tortorella
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:5144-5150
Given the rise of parasite resistance to all currently used antimalarial drugs, the identification of novel chemotypes with unique mechanisms of action is of paramount importance. Since Plasmodium expresses a number of aspartic proteases necessary fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02eeb0ea1a138311e2f07119a77f522
https://doi.org/10.1016/j.bmc.2015.02.050
https://doi.org/10.1016/j.bmc.2015.02.050
Publikováno v:
The Journal of biological chemistry. 292(44)
Apolipoprotein L1 (ApoL1) is a human serum protein conferring resistance to African trypanosomes, and certain ApoL1 variants increase susceptibility to some progressive kidney diseases. ApoL1 has been hypothesized to function like a pore-forming coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a387e2d1a24be6244073f8ff3d9c2133
https://pubmed.ncbi.nlm.nih.gov/28918394
https://pubmed.ncbi.nlm.nih.gov/28918394
Publikováno v:
Journal of Robotic Surgery. 8:255-260
Application of energy in minimally invasive hysterectomy creates thermal injury which may increase vaginal cuff dehiscence. The purpose of this study was to compare vaginal tissue damage in a swine model between the two power settings of ultrasonic e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11af966157c6556cc8414d3a8d7320c3
https://doi.org/10.1007/s11701-014-0464-1
https://doi.org/10.1007/s11701-014-0464-1
Autor:
Mary Campbell, Limei Qin, Li Qin, Zhengxiang He, Jing Xu, Christopher S. Eickhoff, Marvin J. Meyers, Ke Ding, Xiaoyun Lu, David W. Griggs, Wanwan Xu, Michael J. Prinsen, Xiaoping Chen, Francis M. Sverdrup, Peter G. Ruminski, Wentian Zeng, E. Jon Jacobsen, Yongzhi Lu, Xingfen Lang, Zhengchao Tu, Xiaorong Liu, Daniel E. Goldberg, Lu Xin, Micky D. Tortorella, David C. Wood, Jonathan Oliva
Publikováno v:
ACS medicinal chemistry letters. 5(1)
Given the threat of drug resistance, there is an acute need for new classes of antimalarial agents that act via a unique mechanism of action relative to currently used drugs. We have identified a set of druglike compounds within the Tres Cantos Anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6eef58d44ba6c305f6dd3be3cc511c9
https://pubmed.ncbi.nlm.nih.gov/24900778
https://pubmed.ncbi.nlm.nih.gov/24900778
Autor:
Jinping Lai, Barbara Ulmasov, David W. Griggs, Matthew P. Yates, Trisha Bhat, Brent A. Neuschwander-Tetri, Jonathan Oliva, Vanita Talkad, Vladimir Monastyrskiy, Peter G. Ruminski
Publikováno v:
Gastroenterology. 148:S-144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a926d924b02c5d84a5f0e2d65bbaf2a9
https://doi.org/10.1016/s0016-5085(15)30492-3
https://doi.org/10.1016/s0016-5085(15)30492-3