Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Jonathan O Dostrovsky"'
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96026 (2014)
Thalamic deep brain stimulation (DBS) is an effective treatment for tremor, but the mechanisms of action remain unclear. Previous studies of human thalamic neurons to noted transient rebound bursting activity followed by prolonged inhibition after ce
Externí odkaz:
https://doaj.org/article/e306ed977e604c15a3cc65c1880cc928
Publikováno v:
Brain Res
The rostral ventromedial medulla (RVM) plays a key role in the endogenous modulation of nociceptive transmission in the central nervous system (CNS). The primary aim of this study was to examine whether the activities of RVM neurons were related to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebf9f64abdf5f14b6edfdffa5d1ec10
https://europepmc.org/articles/PMC8349861/
https://europepmc.org/articles/PMC8349861/
Autor:
Yoshihisa Tachibana, Atsushi Yoshida, Takafumi Kato, Masayuki Moritani, Jonathan O. Dostrovsky, Sams Sazzad Ali, Tahsinul Haque, Haruka Ohara, Takashi Fujio, Fumihiko Sato
Publikováno v:
Brain Structure and Function. 222:2655-2669
The ascending pathway mediating proprioception from the orofacial region is still not fully known. The present study elucidated the relay of jaw-closing muscle spindle (JCMS) inputs from brainstem to thalamus in rats. We injected an anterograde trace
Autor:
Mojgan Hodaie, Diellor Basha, William D. Hutchison, Andres M. Lozano, Jonathan O. Dostrovsky, Suneil K. Kalia
Publikováno v:
Journal of neurosurgery. 129(4)
The amputation of an extremity is commonly followed by phantom sensations that are perceived to originate from the missing limb. The mechanism underlying the generation of these sensations is still not clear although the development of abnormal oscil
Autor:
Thilo Womelsdorf, Takashi Nakao, Nir Lipsman, Jonathan O. Dostrovsky, Peter Giacobbe, William D. Hutchison, Joachim K. Krauss, Georg Northoff, Andres M. Lozano, Noriaki Kanayama, Clement Hamani, Adam K. Anderson
Publikováno v:
Cortex. 60:139-144
High activity of the default mode network (DMN) has been proposed to be central in processing self-relevant events. Thus far, this hypothesis of DMN function has not been tested directly using neurophysiological techniques. To test for the link betwe
Publikováno v:
European Journal of Pain. 19:202-215
Background The application to the skin of spatially interlaced innocuous warm (40 °C) and cool (20 °C) thermodes (termed a thermal grill – TG) can produce an unusual thermal percept, but the mechanisms remain unclear. Methods We compared the perc
Publikováno v:
Pain. 155:429-435
Glial cells are being increasingly implicated in mechanisms underlying pathological pain, and recent studies suggest glial gap junctions involving astrocytes may contribute. The aim of this study was to examine the effect of a gap junction blocker, c
Publikováno v:
Experimental Neurology. 245:60-71
Parkinson's disease (PD) is accompanied by a significant amount of β-band (11 Hz–30 Hz) neuronal and local field potential (LFP) oscillatory activity in the subthalamic nucleus (STN). Previous studies have shown significant coherence between neuro
Publikováno v:
The Journal of Pain. 14:193-204
The aim of this study was to determine whether pregabalin affects nociceptive behavior and central sensitization in a trigeminal neuropathic pain model. A partial infraorbital nerve transection (p-IONX) or sham operation was performed in adult male r
Publikováno v:
Neuroscience Letters. 526:160-163
Central sensitization and purinergic receptor mechanisms have been implicated as important processes in acute and chronic pain conditions following injury or inflammation of peripheral tissues. This study has documented that application of the P2X(1,