Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jonathan N. Lakins"'
Autor:
Emily S. Bell, Pragya Shah, Noam Zuela-Sopilniak, Dongsung Kim, Alice-Anais Varlet, Julien L.P. Morival, Alexandra L. McGregor, Philipp Isermann, Patricia M. Davidson, Joshua J. Elacqua, Jonathan N. Lakins, Linda Vahdat, Valerie M. Weaver, Marcus B. Smolka, Paul N. Span, Jan Lammerding
Publikováno v:
Oncogene, 41, 4211-4230
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Contains fulltext : 283431.pdf (Publisher’s version ) (Closed access) Aberrations in nuclear size and shape are commonly used to identify cancerous tissue. However, it remains unclear whether the disturbed nuclear structure directly contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70d1cbcd6f62c9638cc7b792ccc5bd7
https://doi.org/10.1038/s41388-022-02420-9
https://doi.org/10.1038/s41388-022-02420-9
Autor:
Valerie M. Weaver, E. S. Hwang, Aastha Chauhan, Brian Ruffell, Jonathan N. Lakins, Lisa M. Coussens, O. Maller, P. T. Thanh, Zena Werb, Peter Kabos, Travis Nemkov, Alexander S. Barrett, Tina Gruosso, Allison P. Drain, Olöf Bjarnadottir, Hellen Kuasne, Jessica Gruenberg, Andrew C. Nelson, Irene Acerbi, Morag Park, J. M. Barnes, Kirk C. Hansen, Signe Borgquist, Aqsa Nasir
Collagen deposition and stromal stiffening accompany malignancy, compromise treatment, and promote tumor aggression. Clarifying the molecular nature of and the factors that regulate extracellular matrix stiffening in tumors should identify biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd269832452581ee5a56d2c868d8294
https://doi.org/10.1101/2020.02.13.948141
https://doi.org/10.1101/2020.02.13.948141
Autor:
Matthew G. Rubashkin, Guanqing Ou, David J. Odde, Michael W. Davidson, Alexander R. Dunn, J. Matthew Barnes, Xin Ye, Jan Lammerding, Emily Bell, Alexandra L. McGregor, Louis S. Prahl, Christopher C. DuFort, Valerie M. Weaver, Steven Tan, Jonathan N. Lakins, Alice C. Chang, FuiBoon Kai, Armen H. Mekhdjian, Laralynne Przybyla, Luke Cassereau, Michael W. Pickup
Publikováno v:
Molecular Biology of the Cell
Molecular biology of the cell, vol 28, iss 11
Molecular biology of the cell, vol 28, iss 11
Mammary tumor cells adopt a basal-like phenotype when invading through a dense, stiffened, 3D matrix. These cells exert higher integrin-mediated traction forces, consistent with a physical motor-clutch model, display an altered molecular organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa5ffb4115b47a9324a3c6bf9543f97
http://europepmc.org/articles/PMC5449147
http://europepmc.org/articles/PMC5449147
Autor:
Melody A. Swartz, Jan Liphardt, Shelley Hwang, Brian Ruffell, Irene Acerbi, C Yunn-Yi, Quanming Shi, Valerie M. Weaver, Hongmei Yu, Jennifer M. Munson, Alfred Au, Jonathan N. Lakins, LM Coussen, Janna K. Mouw, S. Zheng
Publikováno v:
Cancer Research. 73:S2-06
Tumor progression is influenced by the dynamic interplay between the genetically-modified epithelium and the associated microenvironment. We previously showed that the extra-cellular matrix (ECM) progressively stiffens as mammary tumors evolve, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7587a920c60c6defff7b65239afb4d
https://doi.org/10.1158/0008-5472.sabcs13-s2-06
https://doi.org/10.1158/0008-5472.sabcs13-s2-06
Autor:
Raghu Kalluri, Yekaterina A. Miroshnikova, Hideaki Ijichi, Jonathan N. Lakins, Agnieszka E. Gorska, Jose Lopez, Harold L. Moses, Irene Acerbi, Valerie M. Weaver, Elena Kassianidou, Hanane Laklai, Sergey V. Novitskiy
Publikováno v:
Tumor Biology.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a profound fibrotic response that contributes to tumor aggression and treatment resistance (Farrow et al., Journal of Surgical Research, 2008). Yet, the molecular mechanisms linking tissue t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::724f34991f0597b7a75d0cc0d6edae52
https://doi.org/10.1158/1538-7445.panca2012-a47
https://doi.org/10.1158/1538-7445.panca2012-a47