Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jonathan Michaud-Levesque"'
Ablation of PRMT6 reveals a role as a negative transcriptional regulator of the p53 tumor suppressor
Autor:
Frédérick A. Mallette, Stéphane Richard, Gillian Vogel, Mathieu Neault, Jonathan Michaud-Levesque
Publikováno v:
Nucleic Acids Research
Arginine methylation of histones is a well-known regulator of gene expression. Protein arginine methyltransferase 6 (PRMT6) has been shown to function as a transcriptional repressor by methylating the histone H3 arginine 2 [H3R2(me2a)] repressive mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c431002376f104dad3da6a1685235d3
http://europepmc.org/articles/PMC3479207
http://europepmc.org/articles/PMC3479207
Publikováno v:
Experimental Cell Research. 318:925-935
Evidence has suggested that STAT3 functions as an oncogene in gliomagenesis. As a consequence, changes in the inflammatory microenvironment are thought to promote tumor development. Regardless of its origin, cancer-related inflammation has many tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00390fa2f61225ba9b7f32eee2c2aa6
https://doi.org/10.1016/j.yexcr.2012.02.017
https://doi.org/10.1016/j.yexcr.2012.02.017
Publikováno v:
Medicinal Chemistry Reviews - Online. 2:49-58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7db8ac1aefbfc2567ff804c0a92e09d7
https://doi.org/10.2174/1567203052997095
https://doi.org/10.2174/1567203052997095
Autor:
Denis Gingras, Jonathan Michaud-Levesque, Julie Jodoin, Sylvie Lamy, Richard Béliveau, Dominique Boivin, Borhane Annabi, Yanick Bertrand, Michel Demeule
Publikováno v:
Current Medicinal Chemistry-Anti-Cancer Agents. 2:441-463
The concept of cancer prevention by use of naturally occuring substances that could be included in the diet is under investigation as a practical approach towards reducing cancer incidence, and therefore the mortality and morbidity associated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33cccb9acbefcb9397822dd9fe3fd90
https://doi.org/10.2174/1568011023353930
https://doi.org/10.2174/1568011023353930
Autor:
Aimee Iberg, Daehoon Kim, Alexsandra Espejo, Donghang Cheng, Stéphane Richard, Jonathan Michaud-Levesque, Mark T. Bedford
Publikováno v:
The Journal of biological chemistry. 283(6)
Histone tail post-translational modification results in changes in cellular processes, either by generating or blocking docking sites for histone code readers or by altering the higher order chromatin structure. H3K4me3 is known to mark the promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc264056d898c5823abfc5181bc664ce
https://pubmed.ncbi.nlm.nih.gov/18077460
https://pubmed.ncbi.nlm.nih.gov/18077460
Autor:
Naziha Marrakchi, Jonathan Michaud-Levesque, Mohamed El Ayeb, Salma Daoud, Anthony Pilorget, Jacques Marvaldi, Magali Conesa, Richard Béliveau, Michel Demeule, Sameh Sarray, José Luis, Kwang Sik Kim
Publikováno v:
Journal of Cellular Physiology
Journal of Cellular Physiology, Wiley, 2007, 211 (2), pp.307-315. ⟨10.1002/jcp.20935⟩
Journal of Cellular Physiology, 2007, 211 (2), pp.307-315. ⟨10.1002/jcp.20935⟩
Journal of Cellular Physiology, Wiley, 2007, 211 (2), pp.307-315. ⟨10.1002/jcp.20935⟩
Journal of Cellular Physiology, 2007, 211 (2), pp.307-315. ⟨10.1002/jcp.20935⟩
International audience; Integrins play an essential role in endothelial cell motility processes during angiogenesis and thus present interesting targets for the development of new anti-angiogenic agents. Snake venoms naturally contain a variety of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c5efc3448cbb9a5729d8b0d20a3467
https://pubmed.ncbi.nlm.nih.gov/17323383
https://pubmed.ncbi.nlm.nih.gov/17323383
Publikováno v:
Biochemical and biophysical research communications. 353(2)
The expression of melanotransferrin (MTf), a membrane-bound glycoprotein highly expressed in melanomas, is correlated with tumor vascularization and progression, suggesting a proinvasive function associated with MTf in malignant tumors. To test this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef711a957cf7c90591179f359149951
https://pubmed.ncbi.nlm.nih.gov/17196552
https://pubmed.ncbi.nlm.nih.gov/17196552
Publikováno v:
Carcinogenesis. 28(2)
Melanotransferrin (MTf), the membrane-bound human melanoma antigen p97, binds to plasminogen and stimulates its activation, thus regulating a crucial step involved in angiogenesis. In our study, a truncated soluble form of MTf (sMTf) inhibits, in a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b982f8b2f3503a21e0612945c1e7ff1b
https://pubmed.ncbi.nlm.nih.gov/16857721
https://pubmed.ncbi.nlm.nih.gov/16857721
Autor:
Denis Gingras, Albert Moghrabi, Jonathan Michaud-Levesque, Mélanie Blanchette, René Lafleur, Sylvie Lamy, Richard Béliveau, Yves Durocher, Stéphane Barrette
Publikováno v:
Carcinogenesis. 27(5)
Epidemiological studies have shown that a diet rich in fruits and vegetables has a beneficial preventive effect on cardiovascular diseases and cancer by mechanisms that have not yet been elucidated. In this work, we investigated the antiangiogenic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f25f6796fda57dffcaf853b25524e8
https://pubmed.ncbi.nlm.nih.gov/16308314
https://pubmed.ncbi.nlm.nih.gov/16308314
Publikováno v:
Experimental cell research. 308(2)
The activation of plasminogen at the cell surface is a crucial step in cell migration and invasion. In the present study, the effect of membrane-bound melanotransferrin (mMTf), also known as human melanoma antigen p97, on cell surface plasminogen bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5aee95d95fe4f9a0164dee34eca1808
https://pubmed.ncbi.nlm.nih.gov/15936756
https://pubmed.ncbi.nlm.nih.gov/15936756