Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Jonathan McConathy"'
Autor:
Hyewon H. Lee, Daniel M. Blumberger, Eric J. Lenze, Stewart J. Anderson, Deanna M. Barch, Kevin J. Black, Pilar Cristancho, Zafiris J. Daskalakis, Sarah A. Eisenstein, Yiyun Huang, Songye Li, Jennifer Lissemore, Jonathan McConathy, Benoit H. Mulsant, Tarek K. Rajji, Charles F. Reynolds, III, Yi Su, Zhude Tu, Daphne Voineskos, Jordan F. Karp
Publikováno v:
Biological Psychiatry Global Open Science, Vol 2, Iss 2, Pp 127-135 (2022)
Background: The experimental therapeutics approach that combines a placebo-controlled clinical trial with translational neuroscience methods can provide a better understanding of both the clinical and physiological effects of pharmacotherapy. We aime
Externí odkaz:
https://doaj.org/article/20992fc83723446c987b15d5df1a4b83
Autor:
Navkaranbir S. Bajaj, Rajat Kalra, Kartik Gupta, Sudeep Aryal, Indranee Rajapreyar, Steven G. Lloyd, Jonathan McConathy, Sanjiv J. Shah, Sumanth D. Prabhu
Publikováno v:
ESC Heart Failure, Vol 7, Iss 4, Pp 1676-1687 (2020)
Abstract Aims Prior evidence has implicated leucocyte expansion in several cardiovascular disorders, including heart failure (HF) with reduced ejection fraction (rEF). However, the prognostic importance of leucocyte count in HF with preserved EF (HFp
Externí odkaz:
https://doaj.org/article/72f59009e80145ecb31f2d639ff0ffec
Autor:
Maoxue Tang, Guangping Gao, Carlos B. Rueda, Hang Yu, David N. Thibodeaux, Tomoyuki Awano, Kristin M. Engelstad, Maria-Jose Sanchez-Quintero, Hong Yang, Fanghua Li, Huapeng Li, Qin Su, Kara E. Shetler, Lynne Jones, Ryan Seo, Jonathan McConathy, Elizabeth M. Hillman, Jeffrey L. Noebels, Darryl C. De Vivo, Umrao R. Monani
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Glut1-deficiency syndrome is a severe neurodevelopmental disorder characterized by low brain glucose and epileptic seizures. Tanget al. show that in model mice, low Glut1 leads to defects of the brain vasculature, and that AAV9-based gene therapy at
Externí odkaz:
https://doaj.org/article/cfe083483d664856ac5c4ced1381ccce
Autor:
Qing Wang, Gloria J Guzmán Pérez-Carrillo, Maria Rosana Ponisio, Pamela LaMontagne, Sonika Dahiya, Daniel S Marcus, Mikhail Milchenko, Joshua Shimony, Jingxia Liu, Gengsheng Chen, Amber Salter, Parinaz Massoumzadeh, Michelle M Miller-Thomas, Keith M Rich, Jonathan McConathy, Tammie L S Benzinger, Yong Wang
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0225093 (2019)
ObjectivesPrimary brain tumors are composed of tumor cells, neural/glial tissues, edema, and vasculature tissue. Conventional MRI has a limited ability to evaluate heterogeneous tumor pathologies. We developed a novel diffusion MRI-based method-Heter
Externí odkaz:
https://doaj.org/article/d5c24f2c95604db298f893f453a46353
Autor:
Oluwatayo F Ikotun, Bernadette V Marquez, Chaofeng Huang, Kazue Masuko, Miyamoto Daiji, Takashi Masuko, Jonathan McConathy, Suzanne E Lapi
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77476 (2013)
The L-type amino acid transporter-1 (LAT1, SLC7A5) is upregulated in a wide range of human cancers, positively correlated with the biological aggressiveness of tumors, and a promising target for both imaging and therapy. Radiolabeled amino acids such
Externí odkaz:
https://doaj.org/article/19c057eff34e4e88a548fce5314a1002
Autor:
Jonathan McConathy, Dong Zhou, Stephany E. Shockley, Lynne A. Jones, Elizabeth A. Griffin, Hsiaoju Lee, Susan J. Adams, Robert H. Mach
Publikováno v:
Molecular Imaging, Vol 9 (2010)
The ( R )- and ( S )-enantiomers of 2-amino-3-[1-(2-[ 18 F]fluoroethyl)-1 H -[1,2,3]triazol-4-yl]propanoic acid (4) were synthesized and evaluated in the rat 9L gliosarcoma brain tumor model using cell uptake assays, biodistribution studies, and micr
Externí odkaz:
https://doaj.org/article/84dd44c1611543ef8828b3197d110b81
Autor:
Talene A. Yacoubian, Yu‐Hua Dean Fang, Adam Gerstenecker, Amy Amara, Natividad Stover, Lauren Ruffrage, Christopher Collette, Richard Kennedy, Yue Zhang, Huixian Hong, Hongwei Qin, Jonathan McConathy, Etty N. Benveniste, David G. Standaert
Publikováno v:
Movement Disorders.
Autor:
Richard T. Hoppe, Ranjana H. Advani, Weiyun Z. Ai, Richard F. Ambinder, Philippe Armand, Celeste M. Bello, Cecil M. Benitez, Weina Chen, Bouthaina Dabaja, Megan E. Daly, Leo I. Gordon, Neil Hansen, Alex F. Herrera, Ephraim P. Hochberg, Patrick B. Johnston, Mark S. Kaminski, Christopher R. Kelsey, Vaishalee P. Kenkre, Nadia Khan, Ryan C. Lynch, Kami Maddocks, Jonathan McConathy, Monika Metzger, David Morgan, Carolyn Mulroney, Sheeja T. Pullarkat, Rachel Rabinovitch, Karen C. Rosenspire, Stuart Seropian, Randa Tao, Pallawi Torka, Jane N. Winter, Joachim Yahalom, Joanna C. Yang, Jennifer L. Burns, Mallory Campbell, Hema Sundar
Publikováno v:
Journal of the National Comprehensive Cancer Network. 20:322-334
Hodgkin lymphoma (HL) is an uncommon malignancy of B-cell origin. Classical HL (cHL) and nodular lymphocyte–predominant HL are the 2 main types of HL. The cure rates for HL have increased so markedly with the advent of modern treatment options that
Autor:
Kevin J. Black, Jennifer I. Lissemore, Zafiris J. Daskalakis, Tarek K. Rajji, Jonathan McConathy, Jordan F. Karp, Songye Li, Zhude Tu, Hyewon Helen Lee, Daphne Voineskos, Benoit H. Mulsant, Eric J. Lenze, M Deanna, Daniel M. Blumberger, Yi Su, Pilar Cristancho, Sarah A. Eisenstein, Yiyun Huang, Charles F. Reynolds, Stewart J. Anderson
Publikováno v:
Biological Psychiatry Global Open Science. 2:127-135
Background The experimental therapeutics approach that combines a placebo-controlled clinical trial with translational neuroscience methods can provide a better understanding of both the clinical and physiological effects of pharmacotherapy. We aimed
Autor:
Shaney Flores, Charles D. Chen, Yi Su, Aylin Dincer, Sarah J. Keefe, Gloria Guzman Perez‐Carrillo, Russ C. Hornbeck, Manu S. Goyal, Andrei G. Vlassenko, Sally Schwarz, Michael L. Nickels, Dean F Wong, Zhude Tu, Jonathan McConathy, John C. Morris, Tammie L.S. Benzinger, Brian A. Gordon
Publikováno v:
Alzheimer's & Dementia. 18