Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonathan Manke"'
Autor:
Alexis F. League, Barkha J. Yadav-Samudrala, Ramya Kolagani, Calista A. Cline, Ian R. Jacobs, Jonathan Manke, Micah J. Niphakis, Benjamin F. Cravatt, Aron H. Lichtman, Bogna M. Ignatowska-Jankowska, Sylvia Fitting
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHuman immunodeficiency virus (HIV) affects nearly 40 million people globally, with roughly 80% of all people living with HIV receiving antiretroviral therapy. Antiretroviral treatment suppresses viral load in peripheral tissues but does not
Externí odkaz:
https://doaj.org/article/8c79ef5970b94294a9b7f4e26a0627ff
Autor:
Rafia Virk, Nicole Buddenbaum, Abrar Al-Shaer, Michael Armstrong, Jonathan Manke, Nichole Reisdorph, Selin Sergin, Jenifer I. Fenton, E. Diane Wallace, Brandie M. Ehrmann, Hannah B. Lovins, Kymberly M. Gowdy, M Ryan Smith, Gregory J. Smith, Samir N.P. Kelada, Saame Raza Shaikh
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 10, Pp 100267- (2022)
Obesity exacerbates inflammation upon lung injury; however, the mechanisms by which obesity primes pulmonary dysregulation prior to external injury are not well studied. Herein, we tested the hypothesis that obesity dysregulates pulmonary PUFA metabo
Externí odkaz:
https://doaj.org/article/bd1ea448d6a44136a15c720385d32004
Autor:
Kedir N. Turi, Cole R. Michel, Jonathan Manke, Katrina A. Doenges, Nichole Reisdorph, Alison K. Bauer
Publikováno v:
Metabolites, Vol 13, Iss 3, p 406 (2023)
Allergy and asthma pathogenesis are associated with the dysregulation of metabolic pathways. To understand the effects of allergen sensitization on metabolic pathways, we conducted a multi-omics study using BALB/cJ mice sensitized to house dust mite
Externí odkaz:
https://doaj.org/article/e741711d4a764bcfab7823a1a1db9dbb
Autor:
Kristen J. Polinski, Michael Armstrong, Jonathan Manke, Jennifer Seifert, Tessa Crume, Fan Yang, Michael Clare-Salzler, V. Michael Holers, Nichole Reisdorph, Jill M. Norris
Publikováno v:
Metabolites, Vol 11, Iss 3, p 137 (2021)
Oxylipins derived from omega-3 and -6 fatty acids are actively involved in inflammatory and immune processes and play important roles in human disease. However, as the interest in oxylipins increases, questions remain regarding which molecules are de
Externí odkaz:
https://doaj.org/article/eb1e3a6a19624d14a7a666fa94790ba8
Autor:
Randi K. Johnson, Jonathan Manke, Monica Campbell, Michael Armstrong, Meher Preethi Boorgula, Gabriela Pinheiro, Cinthia Vila Nova Santana, Rasika A. Mathias, Kathleen C. Barnes, Alvaro Cruz, Nichole Reisdorph, Camila A. Figueiredo
Publikováno v:
The Journal of allergy and clinical immunology. 150(4)
Lipid mediators, bioactive products of polyunsaturated fatty acid metabolism, contribute to inflammation initiation and resolution in allergic diseases; however, their presence in lung-related biosamples has not been fully described.We aimed to quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21473f8d89a3514f00fe57114210fa2
https://pubmed.ncbi.nlm.nih.gov/36029891
https://pubmed.ncbi.nlm.nih.gov/36029891
Autor:
Kevin Quinn, Michael Armstrong, Jonathan Manke, Matthew Vander Ploeg, Nichole Reisdorph, Saame Raza Shaikh
Publikováno v:
Prostaglandins Leukot Essent Fatty Acids
Obesity drives an imbalanced signature of specialized pro-resolving mediators (SPM). Herein, we investigated if high fat diet-induced obesity dysregulates the concentration of SPM intermediates in the brains of C57BL/6 J mice. Furthermore, given the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ada738b769e83244c671ecf7cd364b
https://europepmc.org/articles/PMC8633202/
https://europepmc.org/articles/PMC8633202/
Autor:
Victoria R. Adams, Yujiao Zu, Naima Moustaid-Moussa, Ian M. Carroll, Michael Armstrong, Jonathan Manke, Saame Raza Shaikh, Arion Kennedy, Nicole Reisdorph, Anandita Pal, Shan Sun
Publikováno v:
Biochim Biophys Acta Mol Cell Biol Lipids
Eicosapentaenoic acid (EPA) ethyl esters are of interest given their clinical approval for lowering circulating triglycerides and cardiometabolic disease risk. EPA ethyl esters prevent metabolic complications driven by a high fat diet in male mice; h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa7fae53978a30f705e2021d4ed4137
https://europepmc.org/articles/PMC8627244/
https://europepmc.org/articles/PMC8627244/
Autor:
Michael J Yaeger, Espen E. Spangenburg, Kymberly M Gowdy, Anandita Pal, Brita Kilburg-Basnyat, Katelyn Dunigan-Russell, Michael Armstrong, S Raza Shaikh, Nichole Reisdorph, Johanna L. Hannan, Miles X Hodge, Sky W Reece, Robert M. Tighe, Dorothy J. You, Jonathan Manke, Debra A Tokarz, Bin Luo, James C. Bonner
Publikováno v:
Toxicol Sci
Ozone (O3) is a criteria air pollutant known to increase the morbidity and mortality of cardiopulmonary diseases. This occurs through a pulmonary inflammatory response characterized by increased recruitment of immune cells into the airspace, pro-infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d74ee6662ec21c4a0181c3b246751a
https://pubmed.ncbi.nlm.nih.gov/34175951
https://pubmed.ncbi.nlm.nih.gov/34175951
Autor:
Nichole Reisdorph, Ross S. Osgood, Dominik Reinhold, Brad L. Upham, Michael Armstrong, Lauren A. Vanderlinden, Katelyn J. Siegrist, Kevin Quinn, Jonathan Manke, Marc R. Elie, Alison K. Bauer, Kalpana Velmurugan, Laura Saba, Deedee Romo
Publikováno v:
Toxicol Sci
Low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a734abfe3eb11c603edf890e4721ead3
https://doi.org/10.1093/toxsci/kfz030
https://doi.org/10.1093/toxsci/kfz030
Autor:
Michael J. Clare-Salzler, V. Michael Holers, Fan Yang, Jonathan Manke, Jill M. Norris, Kristen J. Polinski, Nichole Reisdorph, Jennifer Seifert, Michael Armstrong, Tessa L. Crume
Publikováno v:
Metabolites
Volume 11
Issue 3
Metabolites, Vol 11, Iss 137, p 137 (2021)
Volume 11
Issue 3
Metabolites, Vol 11, Iss 137, p 137 (2021)
Oxylipins derived from omega-3 and -6 fatty acids are actively involved in inflammatory and immune processes and play important roles in human disease. However, as the interest in oxylipins increases, questions remain regarding which molecules are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db1bba3d9b5605849594e55ccdf975b3