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Caloric restriction (CR) and endurance exercise elicit wide-ranging health benefits including reduced risk of select cancers. In addition, diet composition influences oncogenesis, although its interactions with exercise and CR are not well understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::937131cc23faff12e176ff33336f2af8
https://doi.org/10.1158/1940-6207.c.6547655.v1
https://doi.org/10.1158/1940-6207.c.6547655.v1
Supplemental Data from Caloric Restriction Prevents Carcinogen-Initiated Liver Tumorigenesis in Mice
Fig. S1. Phenotypic and metabolic parameters are influenced by Ex and CR. Fig. S2. CR modulates additional markers of hepatic inflammation and immune cell infiltration. Fig. S3. CR causes divergence of genes in comparison to CTL mice. Fig. S4. CR aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7387518cf049ec516759c6d090b5d8f9
https://doi.org/10.1158/1940-6207.22534793
https://doi.org/10.1158/1940-6207.22534793
Autor:
Jessica L. Lapiro, J C Manivel, Heng Wu, Laurie L. Shekels, Douglas G. Mashek, Jeffrey H. Albrecht, Jonathan M. Ploeger, Sushama Kamarajugadda, Mara T. Mashek
Publikováno v:
Hepatology Communications
During normal proliferation, hepatocytes accumulate triglycerides (TGs) in lipid droplets (LDs), but the underlying mechanisms and functional significance of this steatosis are unknown. In the current study, we examined the coordinated regulation of
Publikováno v:
Cancer Prevention Research. 10:660-670
Caloric restriction (CR) and endurance exercise elicit wide-ranging health benefits including reduced risk of select cancers. In addition, diet composition influences oncogenesis, although its interactions with exercise and CR are not well understood
Autor:
Mallory P. Franklin, Douglas G. Mashek, Jonathan M. Ploeger, Aishwarya Sathyanarayan, Salmaan A. Khan
Publikováno v:
Hepatology. 62:964-967
Hepatic steatosis is defined by the accumulation of lipid droplets (LDs). Once thought to be only inert energy storage depots, LDs are increasingly recognized as organelles that have important functions in hepatocytes beyond lipid storage. The lipid