Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jonathan M. Oyler"'
Publikováno v:
Rapid Communications in Mass Spectrometry.
Carfentanil, an opioid 10K times more potent than morphine, has no licit clinical use. A powerful CNS depressant, it has been identified increasingly as the cause of overdose death in the United States. Because it is highly lipophilic, the law enforc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f523e0f1a654ed13965ce1e20f49ae6d
https://doi.org/10.1002/rcm.9420
https://doi.org/10.1002/rcm.9420
Bottom-up mass spectrometry-based protein analysis methods employing protease digestion are routinely used to identify and characterize proteins with high specificity and sensitivity. Method performance is generally measured by sequence coverage capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bfe16d3c6c3057d705602713fed27d2
https://irep.ntu.ac.uk/id/eprint/42560/1/1426606_a1594_Kilgour.pdf
https://irep.ntu.ac.uk/id/eprint/42560/1/1426606_a1594_Kilgour.pdf
Publikováno v:
Toxicology in Vitro. 62:104696
There is growing concern regarding potential occupational exposures to the ultra-potent synthetic opioid carfentanil. However, little data are available on the toxicity of carfentanil in humans, particularly for dermal exposures. To begin to address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfc2b6132cd95c6e373f88f2957a8e2
https://doi.org/10.1016/j.tiv.2019.104696
https://doi.org/10.1016/j.tiv.2019.104696
Publikováno v:
Journal of Analytical Toxicology. 39:96-105
Organophosphate nerve agents (OPNAs) are some of the most widely used and proliferated chemical warfare agents. As evidenced by recent events in Syria, these compounds remain a serious military and terrorist threat to human health because of their to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4520774791a23033c4f8205c3d41e3ef
https://doi.org/10.1093/jat/bku135
https://doi.org/10.1093/jat/bku135
Autor:
Jean Mukherjee, Edwin J. Vazquez-Cintron, Philip A. Band, Suzanne R. Kalb, Phillip H. Beske, Bao Q. Tran, Christopher A. Angeles, Elliot J. Glotfelty, Konstantin Ichtchenko, Charles B. Shoemaker, Luis Tenezaca, Jonathan M. Oyler, Aurelia Syngkon, Patrick M. McNutt
Publikováno v:
Scientific Reports
Botulinum neurotoxin (BoNT) binds to and internalizes its light chain into presynaptic compartments with exquisite specificity. While the native toxin is extremely lethal, bioengineering of BoNT has the potential to eliminate toxicity without disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a353634bc310e16c72d26832caacb7b1
Autor:
Jonathan M. Oyler, Robert A. Moyer, Daniel Angelini, Neil S Jensen, Harry Salem, Kristen L. Willis, Charles Hong, Russell M. Dorsey
Publikováno v:
Inhalation Toxicology. 25:37-62
Chemical warfare agents (CWAs) as well as biological toxins present a significant inhalation injury risk to both deployed warfighters and civilian targets of terrorist attacks. Inhalation of many CWAs and biological toxins can induce severe pulmonary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d89d8220c4ec2eb20860617bb68ae8
https://doi.org/10.3109/08958378.2012.750406
https://doi.org/10.3109/08958378.2012.750406
Publikováno v:
Therapeutic Drug Monitoring. 26:664-672
Methamphetamine is widely abused for its euphoric effects. Our objectives were to characterize the urinary pharmacokinetics of methamphetamine and amphetamine after controlled methamphetamine administration to humans and to improve the interpretation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8004b3e0095269ec0854f511175a7aa
https://doi.org/10.1097/00007691-200412000-00013
https://doi.org/10.1097/00007691-200412000-00013
Autor:
Robert H. Lambeth, MyVan Baranoski, Jonathan M. Oyler, Bao Q. Tran, Sanyo M. Mathew, Kathleen J. Housman
Publikováno v:
Journal of Applied Polymer Science. 134:44941
We present a detailed investigation of the aminolysis of six-membered cyclic carbonates to form (poly)hydroxyurethanes. Model reactions between hexyl amine and trimethylene carbonate were performed under different conditions where we surveyed the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbd4b806f5d2dc2c872c536d086659b7
https://doi.org/10.1002/app.44941
https://doi.org/10.1002/app.44941
Publikováno v:
Journal of Analytical Toxicology. 24:530-535
Allegations of illicit hydrocodone use have been made against individuals who were taking physician-prescribed oral codeine but denied hydrocodone use. Drug detection was based on positive urine opiate immunoassay results with subsequent confirmation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9a9e2353d1f431229422e2e07983c01
https://doi.org/10.1093/jat/24.7.530
https://doi.org/10.1093/jat/24.7.530