Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jonathan M. Mudge"'
Autor:
A.M. Whited, Irwin Jungreis, Jeffre Allen, Christina L. Cleveland, Jonathan M. Mudge, Manolis Kellis, John L. Rinn, Loren E. Hough
Publikováno v:
Biophysical Reports, Vol 4, Iss 3, Pp 100167- (2024)
Significant efforts have been made to characterize the biophysical properties of proteins. Small proteins have received less attention because their annotation has historically been less reliable. However, recent improvements in sequencing, proteomic
Externí odkaz:
https://doaj.org/article/061a0541e88540b1b70464949f95f35e
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract The synthesis of most proteins begins at AUG codons, yet a small number of non-AUG initiated proteoforms are also known. Here we analyse a large number of publicly available Ribo-seq datasets to identify novel, previously uncharacterised non
Externí odkaz:
https://doaj.org/article/14d6f587a3ea4037a0db7d86278ff798
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5270963e2d764e298a6b93db10594636
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-24 (2020)
Abstract Background The introduction of novel CTCF binding sites in gene regulatory regions in the rodent lineage is partly the effect of transposable element expansion, particularly in the murine lineage. The exact mechanism and functional impact of
Externí odkaz:
https://doaj.org/article/7852eff7c2554055be7936bec70e00c6
Autor:
Yousuf A. Khan, Irwin Jungreis, James C. Wright, Jonathan M. Mudge, Jyoti S. Choudhary, Andrew E. Firth, Manolis Kellis
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background POLG, located on nuclear chromosome 15, encodes the DNA polymerase γ(Pol γ). Pol γ is responsible for the replication and repair of mitochondrial DNA (mtDNA). Pol γ is the only DNA polymerase found in mitochondria for most ani
Externí odkaz:
https://doaj.org/article/538bb7803ef24b5c896e5f91b7bc7e25
Autor:
Luigi Grassi, Osagie G. Izuogu, Natasha A.N. Jorge, Denis Seyres, Mariona Bustamante, Frances Burden, Samantha Farrow, Neda Farahi, Fergal J. Martin, Adam Frankish, Jonathan M. Mudge, Myrto Kostadima, Romina Petersen, John J. Lambourne, Sophia Rowlston, Enca Martin-Rendon, Laura Clarke, Kate Downes, Xavier Estivill, Paul Flicek, Joost H.A. Martens, Marie-Laure Yaspo, Hendrik G. Stunnenberg, Willem H. Ouwehand, Fabio Passetti, Ernest Turro, Mattia Frontini
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Transcriptional profiling of hematopoietic cell subpopulations has helped to characterize the developmental stages of the hematopoietic system and the molecular bases of malignant and non-malignant blood diseases. Previously, only the genes targeted
Externí odkaz:
https://doaj.org/article/fc260f918bfb4ac080d707f06026c2c3
Autor:
Julien Lagarde, Barbara Uszczynska-Ratajczak, Javier Santoyo-Lopez, Jose Manuel Gonzalez, Electra Tapanari, Jonathan M. Mudge, Charles A. Steward, Laurens Wilming, Andrea Tanzer, Cédric Howald, Jacqueline Chrast, Alicia Vela-Boza, Antonio Rueda, Francisco J. Lopez-Domingo, Joaquin Dopazo, Alexandre Reymond, Roderic Guigó, Jennifer Harrow
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Long non-coding RNAs are increasingly recognised to be important factors in regulating cellular processes and comprise a large faction of the transcriptome, however most are uncharacterised. Here the authors present RACE-Seq, a tool to improve and ex
Externí odkaz:
https://doaj.org/article/4bde9d48e3b14a859a3989164764bb06
Autor:
Susanna Pagni, Helena Martins Custodio, Adam Frankish, Jonathan M Mudge, James D Mills, Sanjay M Sisodiya
Publikováno v:
Human Molecular Genetics. 32:1753-1763
Pathogenic variations in the sodium voltage-gated channel alpha subunit 1 (SCN1A) gene are responsible for multiple epilepsy phenotypes, including Dravet syndrome, febrile seizures (FS) and genetic epilepsy with FS plus. Phenotypic heterogeneity is a
Autor:
John R. Prensner, Jennifer G. Abelin, Leron W. Kok, Karl R. Clauser, Jonathan M. Mudge, Jorge Ruiz-Orera, Michal Bassani-Sternberg, Eric W. Deutsch, Sebastiaan van Heesch
Publikováno v:
bioRxiv
Ribosome profiling (Ribo-seq) has proven transformative for our understanding of the human genome and proteome by illuminating thousands of non-canonical sites of ribosome translation outside of the currently annotated coding sequences (CDSs). A cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a840ce9ffe188ebdd004e14f72306e
https://doi.org/10.1101/2023.05.16.541049
https://doi.org/10.1101/2023.05.16.541049
Autor:
Katri Silvennoinen, Kinga Gawel, Despina Tsortouktzidis, Julika Pitsch, Saud Alhusaini, Karen M. J. van Loo, Richard Picardo, Zuzanna Michalak, Susanna Pagni, Helena Martins Custodio, James Mills, Christopher D. Whelan, Greig I. de Zubicaray, Katie L. McMahon, Wietske van der Ent, Karolina J. Kirstein-Smardzewska, Ettore Tiraboschi, Jonathan M. Mudge, Adam Frankish, Maria Thom, Margaret J. Wright, Paul M. Thompson, Susanne Schoch, Albert J. Becker, Camila V. Esguerra, Sanjay M. Sisodiya
Publikováno v:
Acta Neuropathol (Berl) 144(1), 107-127 (2022). doi:10.1007/s00401-022-02429-0
Acta Neuropathologica
Acta Neuropathologica
Acta Neuropathol (Berl) 144(1), 107-127 (2022). doi:10.1007/s00401-022-02429-0
Published by Springer, Berlin ; Heidelberg
Published by Springer, Berlin ; Heidelberg