Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Jonathan M. Mansbach"'
Autor:
Ryohei Shibata, Zhaozhong Zhu, Michihito Kyo, Tadao Ooka, Robert J. Freishtat, Jonathan M. Mansbach, Marcos Pérez-Losada, Carlos A. Camargo, Jr., Kohei Hasegawa
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104742- (2023)
Summary: Background: Bronchiolitis is a leading cause of infant hospitalization. Recent research suggests the heterogeneity within bronchiolitis and the relationship of airway viruses and bacteria with bronchiolitis severity. However, little is known
Externí odkaz:
https://doaj.org/article/e87c8fd0a5384e46a8b566686d929375
Autor:
Son H. McLaren, Ying (Shelly) Qi, Janice A. Espinola, Jonathan M. Mansbach, Peter S. Dayan, Carlos A. Camargo Jr
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Objective Bronchiolitis within the first 3 months of life is a risk factor for more severe illness. We aimed to identify characteristics associated with mild bronchiolitis in infants ≤90 days old presenting to the emergency department (ED)
Externí odkaz:
https://doaj.org/article/bff693dddd6841cb8b958e7f26247e19
Autor:
Michimasa Fujiogi, Yoshihiko Raita, Marcos Pérez-Losada, Robert J. Freishtat, Juan C. Celedón, Jonathan M. Mansbach, Pedro A. Piedra, Zhaozhong Zhu, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Bronchiolitis is major cause of infection, morbidity and hospitalisation. Here the authors apply transcriptomic based assessment of the host response, microbiome composition and function, and associate this to bronchiolitis severity.
Externí odkaz:
https://doaj.org/article/eb3de97ea67e48ba9b6b652ed2a65779
Autor:
Ryohei Shibata, Zhaozhong Zhu, Tadao Ooka, Robert J. Freishtat, Jonathan M. Mansbach, Marcos Pérez-Losada, Ignacio Ramos-Tapia, Stephen Teach, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundBronchiolitis is the leading cause of infant hospitalization in U.S. and is associated with increased risk for childhood asthma. Immunoglobulin E (IgE) not only plays major roles in antiviral immune responses and atopic predisposition, but
Externí odkaz:
https://doaj.org/article/6de182c0c4ad452ea136fc2f7c803c6b
Autor:
Yoshihiko Raita, Marcos Pérez-Losada, Robert J. Freishtat, Brennan Harmon, Jonathan M. Mansbach, Pedro A. Piedra, Zhaozhong Zhu, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Respiratory syncytial virus (RSV) bronchiolitis during infancy is a major risk factor for asthma development. Here, Raita et al. integrate clinical data with airway microbiome, transcriptome, and metabolome data and identity four endotypes with diffe
Externí odkaz:
https://doaj.org/article/6c472cd962914c2c8b3f0373e27d5a0a
Publikováno v:
Nutrients, Vol 15, Iss 10, p 2379 (2023)
Improving lung health in children requires understanding the risk factors for decreased lung function. Our objective was to investigate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and lung function in children. We analyzed data
Externí odkaz:
https://doaj.org/article/1e9bd37ded7348abb365eb94dafb2cc4
Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis
Autor:
David T. J. Broderick, David W. Waite, Robyn L. Marsh, Carlos A. Camargo, Paul Cardenas, Anne B. Chang, William O. C. Cookson, Leah Cuthbertson, Wenkui Dai, Mark L. Everard, Alain Gervaix, J. Kirk Harris, Kohei Hasegawa, Lucas R. Hoffman, Soo-Jong Hong, Laurence Josset, Matthew S. Kelly, Bong-Soo Kim, Yong Kong, Shuai C. Li, Jonathan M. Mansbach, Asuncion Mejias, George A. O’Toole, Laura Paalanen, Marcos Pérez-Losada, Melinda M. Pettigrew, Maxime Pichon, Octavio Ramilo, Lasse Ruokolainen, Olga Sakwinska, Patrick C. Seed, Christopher J. van der Gast, Brandie D. Wagner, Hana Yi, Edith T. Zemanick, Yuejie Zheng, Naveen Pillarisetti, Michael W. Taylor
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Introduction: The airway microbiota has been linked to specific paediatric respiratory diseases, but studies are often small. It remains unclear whether particular bacteria are associated with a given disease, or if a more general, non-specific micro
Externí odkaz:
https://doaj.org/article/c272f2281790452aa37d24bfbb50f88d
Autor:
Michihito Kyo, Zhaozhong Zhu, Makiko Nanishi, Ryohei Shibata, Tadao Ooka, Robert J. Freishtat, Jonathan M. Mansbach, Carlos A. Camargo, Kohei Hasegawa
Publikováno v:
Metabolites, Vol 12, Iss 8, p 674 (2022)
Infants hospitalized for bronchiolitis are at high risk for asthma. Glutathione-related metabolites may antagonize oxidative stress, which induces airway injuries in respiratory infection and subsequent airway remodeling. However, little is known abo
Externí odkaz:
https://doaj.org/article/551d182af48f4463aed095d879929c22
Autor:
Pamela N. Luna, Kohei Hasegawa, Nadim J. Ajami, Janice A. Espinola, David M. Henke, Joseph F. Petrosino, Pedro A. Piedra, Ashley F. Sullivan, Carlos A. Camargo, Chad A. Shaw, Jonathan M. Mansbach
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background The airway microbiome is a subject of great interest for the study of respiratory disease. Anterior nare samples are more accessible than samples from deeper within the nasopharynx. However, the correlation between the microbiota
Externí odkaz:
https://doaj.org/article/6af212d5a9ca4059a982bb3c8ce9f314
Autor:
Kohei Hasegawa, Christopher J. Stewart, Jonathan M. Mansbach, Rachel W. Linnemann, Nadim J. Ajami, Joseph F. Petrosino, Carlos A. Camargo
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Objective Emerging evidence demonstrated that the structure of fecal microbiome is associated with the likelihood of bronchiolitis in infants. However, no study has examined functional profiles of fecal microbiome in infants with bronchiolit
Externí odkaz:
https://doaj.org/article/61bd866709364077955a9e49425c0e15