Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jonathan M. Ellis"'
Publikováno v:
Molecules, Vol 26, Iss 2, p 270 (2021)
YqhD, an E. coli alcohol/aldehyde oxidoreductase, is an enzyme able to produce valuable bio-renewable fuels and fine chemicals from a broad range of starting materials. Herein, we report the first computational solution-phase structure-dynamics analy
Externí odkaz:
https://doaj.org/article/b9d3e25dae904da88f42c4193f7a30b6
Autor:
Jonathan M, Ellis, Andrew R, Buller
Publikováno v:
Nature chemical biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f48361a0971201a8e5c3d48e7012b36a
https://pubmed.ncbi.nlm.nih.gov/36509905
https://pubmed.ncbi.nlm.nih.gov/36509905
Autor:
Prasanth Kumar, Craig A. Bingman, Jonathan M. Ellis, Andrew R. Buller, Grace A Carlson, Anthony Meza
Publikováno v:
ACS Chem Biol
l-Threonine transaldolases (lTTAs) are a poorly characterized class of pyridoxal-5'-phosphate (PLP) dependent enzymes responsible for the biosynthesis of diverse β-hydroxy amino acids. Here, we study the catalytic mechanism of ObiH, an lTTA essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4371cb1a1ebf89367e80dfa71abfe977
https://doi.org/10.1021/acschembio.0c00753
https://doi.org/10.1021/acschembio.0c00753
The formation of carbon-carbon bonds lies at the heart of organic chemistry, but relatively few C-C bond forming enzymes have found their way into the biocatalysis toolbox. We report that the enzyme UstD performs a highly selective decarboxylative al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dd2af0429710903b2ed7d704849783
https://doi.org/10.26434/chemrxiv.14544666.v1
https://doi.org/10.26434/chemrxiv.14544666.v1
Publikováno v:
Molecules, Vol 26, Iss 270, p 270 (2021)
Molecules
Volume 26
Issue 2
Molecules
Volume 26
Issue 2
YqhD, an E. coli alcohol/aldehyde oxidoreductase, is an enzyme able to produce valuable bio-renewable fuels and fine chemicals from a broad range of starting materials. Herein, we report the first computational solution-phase structure-dynamics analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ec42bbc33de652885803242f721c48
https://www.mdpi.com/1420-3049/26/2/270
https://www.mdpi.com/1420-3049/26/2/270
Autor:
Joseph P. Karnes, Jonathan M. Ellis, Olivia A. Hull, Jayangika Niroshani Dahanayake, Chandana Kasireddy, Katie R. Mitchell-Koch, Rajni Verma, Ryan M. Steinert, Derek Hildebrandt
Fluorine NMR spectroscopy has diverse applications, including characterization of chemical reaction mechanisms, protein structure–function studies, and solid-state NMR characterization of crystalline, amorphous, and soft materials. Computational me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9d403d3405c9c52501de124f1e9d68
https://doi.org/10.1016/bs.arnmr.2017.08.002
https://doi.org/10.1016/bs.arnmr.2017.08.002
Autor:
Joseph P. Karnes, Olivia A. Hull, Jonathan M. Ellis, Derek Hildebrandt, Chandana Kasireddy, Katie R. Mitchell-Koch, Jayangika Niroshani Dahanayake, Dylan Morlan
The ability of electronic structure methods (11 density functionals, HF, and MP2 calculations; two basis sets and two solvation models) to accurately calculate the 19 F chemical shifts of 31 structures of fluorinated amino acids and analogues with kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398f0a27bde8c7a4f2a042bb0687aa69
https://europepmc.org/articles/PMC5638705/
https://europepmc.org/articles/PMC5638705/
Publikováno v:
Scientific Reports
Fluorinated amino acids serve as valuable biological probes, by reporting on local protein structure and dynamics through 19F NMR chemical shifts. 2-fluorohistidine and 4-fluorohistidine, studied here with DFT methods, have even more capabilities for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef861c18cbe28de34f1e8bca8bd3f360
http://europepmc.org/articles/PMC5309746
http://europepmc.org/articles/PMC5309746
Ribonuclease A is the oldest model for studying enzymatic mechanisms, yet questions remain about proton transfer within the active site. Seminal work by Jackson et al. (Science, 1994) labeled Ribonuclease A with 4-fluorohistidine, concluding that act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac08af7388624b07bc003e437e81357c
https://europepmc.org/articles/PMC5461937/
https://europepmc.org/articles/PMC5461937/