Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jonathan M. Burg"'
Autor:
Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde, Madison M. Parker, Cari Sagum, Jonathan M. Burg, Nathan Hall, Irina K. Popova, Keli L. Rodriguez, Anup Vaidya, Krzysztof Krajewski, Michael-Christopher Keogh, Mark T. Bedford, Brian D. Strahl
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Plant homeodomain (PHD) fingers are central “readers” of histone post-translational modifications (PTMs) with > 100 PHD finger-containing proteins encoded by the human genome. Many of the PHDs studied to date bind to unmodifie
Externí odkaz:
https://doaj.org/article/42e1fad0bbb845c0b5d819ca89ab4149
Autor:
Jonathan F. Thomas, Marco Igor Valencia-Sánchez, Simone Tamburri, Susan L. Gloor, Samantha Rustichelli, Victoria Godínez-López, Pablo De Ioannes, Rachel Lee, Stephen Abini-Agbomson, Kristjan Gretarsson, Jonathan M. Burg, Allison R. Hickman, Lu Sun, Saarang Gopinath, Hailey Taylor, Matthew J. Meiners, Marcus A. Cheek, William Rice, Evgeny Nudler, Chao Lu, Michael-Christopher Keogh, Diego Pasini, Karim-Jean Armache
Publikováno v:
bioRxiv
The maintenance of gene expression patterns during metazoan development is achieved by the actions of Polycomb group (PcG) complexes. An essential modification marking silenced genes is monoubiquitination of histone H2A lysine 119 (H2AK119Ub) deposit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db25e4b2a5a80a0e97a9d5d66c694d3
https://doi.org/10.1101/2023.02.23.529554
https://doi.org/10.1101/2023.02.23.529554
Autor:
Lu Sun, Hannah Willis, Matthew R. Marunde, Vishnu U. Kumary, Matthew J. Meiners, Saarang Gopinath, Jonathan M. Burg, Bryan J. Venters, Allison Hickman, Zu-Wen Sun, Martis W. Cowles, Pierre Esteve, Hang Gyeong Chin, Chaithanya Ponnaluri, Sriharsa Pradhan, Michael-Christopher Keogh
Publikováno v:
Cancer Research. 83:4728-4728
Chromatin remodeling is mediated by ATP-dependent enzymes that play key roles regulating gene expression and genome replication/repair. Aberrant nucleosome organization from dysregulated chromatin remodeling can severely alter chromatin accessibility
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas Young, Michael-C Keogh, Brian D Strahl
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56293051dfd39cb6a2645e19d0fa20ad
https://doi.org/10.1101/2022.02.28.482307
https://doi.org/10.1101/2022.02.28.482307
Autor:
Matthew R. Marunde, Harrison A. Fuchs, Jonathan M. Burg, Irina K. Popova, Anup Vaidya, Nathan W. Hall, Matthew J. Meiners, Rachel Watson, Sarah A. Howard, Katherine Novitzky, Eileen McAnarney, Marcus A. Cheek, Zu-Wen Sun, Bryan J. Venters, Michael-C. Keogh, Catherine A. Musselman
Histone post-translational modifications (PTMs) play a critical role in chromatin regulation. It has been proposed that these PTMs form localized ‘codes’ that are read by specialized regions (reader domains) in chromatin associated proteins (CAPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cadb227370ba71c1b1a82a94875c1c85
https://doi.org/10.1101/2022.02.21.481373
https://doi.org/10.1101/2022.02.21.481373
Autor:
Håkan Wallén, Andrea L. Johnstone, Saira Z Sheikh, Denis F. Noubouossie, Katherina Aguilera, Maja Månsson, Matthew R. Marunde, Charlotte Thålin, Matthew J. Meiners, Sarah A. Howard, Maud Daleskog, Martis W. Cowles, Zu-Wen Sun, Staffan Lundström, Jonathan M. Burg, Michael-Christopher Keogh, Axel Rosell, Nathan W. Hall, Marcus A. Cheek, Matthew F. Whelihan, Yohei Hisada, Nigel Mackman, Nigel S. Key, Shruti Saxena-Beem
Publikováno v:
Journal of thrombosis and haemostasis : JTH
Background Recent data propose a diagnostic and prognostic capacity for citrullinated histone H3 (H3Cit), a marker of neutrophil extracellular traps (NETs), in pathologic conditions such as cancer and thrombosis. However, current research is hampered
Autor:
Natalia L. Husby, Lu Sun, Hannah Willis, Matthew R. Marunde, Matt J. Meiners, Zachary Gillespie, Rachel Watson, Saarang Gopinath, Jonathan M. Burg, Marcus A. Cheek, Katherine Novitzky, Bryan J. Venters, Zu-Wen Sun, Michael-Christopher Keogh
Publikováno v:
Cancer Research. 82:B015-B015
Chromatin remodeling, driven by ATP-dependent remodeling enzymes, plays key roles in regulating gene expression, genome replication and repair. Aberrant nucleosome organization can severely disrupt these important processes, driving various cancers a
Autor:
Emily J. Rendleman, Scott B. Rothbart, Robert M. Vaughan, Irina K. Popova, Michael-Christopher Keogh, Anup Vaidya, Sarah A. Howard, Zachary J. Dumar, Matthew J. Meiners, Ali Shilatifard, Marc A. Morgan, Rachel Watson, Jonathan M. Burg, Natalia Khalatyan, Matthew R. Marunde
Publikováno v:
Genesdevelopment. 35(23-24)
Mutations in thePHIP/BRWD2chromatin regulator cause the human neurodevelopmental disorder Chung-Jansen syndrome, while alterations inPHIPexpression are linked to cancer. Precisely how PHIP functions in these contexts is not fully understood. Here we
Autor:
Brianne M. Dudiak, Christopher J Podracky, Kenneth R. Maksimchuk, Tri M. Nguyen, Jonathan M. Burg, Dewey G. McCafferty, Maria M. Bednar, Felix O Nwogbo, Raphael H. Valdivia
Publikováno v:
Biochemistry. 58:3527-3536
CPAF (chlamydial protease-like activity factor) is a Chlamydia trachomatis protease that is translocated into the host cytosol during infection. CPAF activity results in dampened host inflammation signaling, cytoskeletal remodeling, and suppressed ne
Autor:
Katharina Schmalkuche, Tamina Rother, Jonathan M. Burgmann, Henrike Voß, Klaus Höffler, Günes Dogan, Arjang Ruhparwar, Jan D. Schmitto, Rainer Blasczyk, Constanca Figueiredo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Heart transplantation is associated with major hurdles, including the limited number of available organs for transplantation, the risk of rejection due to genetic discrepancies, and the burden of immunosuppression. In this study, we demonstrated the
Externí odkaz:
https://doaj.org/article/7159c2abd33b4a21b8e9532868962379