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pro vyhledávání: '"Jonathan M. Borkum"'
Autor:
Jonathan M Borkum
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 4, Pp 609-615 (2018)
The success of naturalistic or therapeutic neuroregeneration likely depends on an internal milieu that facilitates the survival, proliferation, migration, and differentiation of stem cells and their assimilation into neural networks. Migraine attacks
Externí odkaz:
https://doaj.org/article/269b4b17cf66404a871a2151ab6f3064
Autor:
Jonathan M. Borkum
Publikováno v:
Advanced Biology.
Autor:
Jonathan M, Borkum
Publikováno v:
Neurochemical research. 46(8)
People with migraine are prone to a brain energy deficit between attacks, through increased energy demand (hyperexcitable brain) or decreased supply (mitochondrial impairment). However, it is uncertain how this precipitates an acute attack. Here, the
Autor:
Jonathan M. Borkum
Publikováno v:
Headache: The Journal of Head and Face Pain. 58:118-135
Background Previous research has suggested that migraineurs show higher levels of oxidative stress (lipid peroxides) between migraine attacks and that migraine triggers may further increase brain oxidative stress. Oxidative stress is transduced into
Autor:
Jonathan M. Borkum
Publikováno v:
HeadacheReferences. 59(8)
Background Calcitonin gene-related peptide has emerged as a therapeutic target in migraine. Monoclonal antibodies and small molecule receptor antagonists (gepants) directed against CGRP have been approved or are in Phase II or III clinical trials. Fo
Autor:
Jonathan M. Borkum
Publikováno v:
Headache: The Journal of Head and Face Pain. 56:12-35
Background Blau theorized that migraine triggers are exposures that in higher amounts would damage the brain. The recent discovery that the TRPA1 ion channel transduces oxidative stress and triggers neurogenic inflammation suggests that oxidative str
Autor:
Jonathan M. Borkum
Publikováno v:
Journal of Rational-Emotive & Cognitive-Behavior Therapy. 28:4-24
Maladaptive cognitions are widespread and play a significant role in the development of chronic pain. (1) Catastrophizing seems to increase the risk of chronicity. In the laboratory it amplifies temporal summation of pain with repeated stimulation an
Autor:
Jonathan M. Borkum
Publikováno v:
Current Pain and Headache Reports. 14:55-61
Pain sensitivity is an adaptive process affected by expectation, mood, coping, operant conditioning, and the preconscious allocation of attention. Underlying mechanisms may include encoding of similar experiences (eg, depression, loss, pain-distress)
Publikováno v:
British Journal of Psychology. 96:493-503
In painting, composition is commonly defined as the two-dimensional arrangement of elements within the canvas. Each element is considered to have a perceptual weight. The arrangement of these weighted elements determines how balanced a painting is. I