Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Jonathan M Weiss"'
Autor:
Erika M. Palmieri, Ronald Holewinski, Christopher L. McGinity, Ciro L. Pierri, Nunziata Maio, Jonathan M. Weiss, Vincenzo Tragni, Katrina M. Miranda, Tracey A. Rouault, Thorkell Andresson, David A. Wink, Daniel W. McVicar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract M1 macrophages enter a glycolytic state when endogenous nitric oxide (NO) reprograms mitochondrial metabolism by limiting aconitase 2 and pyruvate dehydrogenase (PDH) activity. Here, we provide evidence that NO targets the PDH complex by usi
Externí odkaz:
https://doaj.org/article/c6b5815c95e344bdaaa97f1c13a3f7f7
Autor:
Perkins, Don
Publikováno v:
Theatre Journal, 1997 May 01. 49(2), 253-254.
Externí odkaz:
https://www.jstor.org/stable/3208702
Autor:
Jonathan Rittenhouse
Publikováno v:
Theatre Research in Canada. 21:201-203
Autor:
Caio C. B. Bomfim, Logan Fisher, Eduardo P. Amaral, Lara Mittereder, Katelyn McCann, André A. S. Correa, Sivaranjani Namasivayam, Muthulekha Swamydas, Mahtab Moayeri, Jonathan M. Weiss, Raj Chari, Daniel W. McVicar, Diego L. Costa, Maria R. D’Império Lima, Alan Sher
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Irg1 is an enzyme that generates itaconate, a metabolite that plays a key role in the regulation of inflammatory responses. Previous studies have implicated Irg1 as an important mediator in preventing excessive inflammation and tissue damage in Mycob
Externí odkaz:
https://doaj.org/article/829c533eabff4b7a98e063262dae07c5
Autor:
Jill W. Ford, Marieli Gonzalez-Cotto, Alexander W. MacFarlane, Suraj Peri, O. M. Zack Howard, Jeffrey J. Subleski, Karen J. Ruth, Mohammed Haseebuddin, Tahseen Al-Saleem, Youfeng Yang, Pat Rayman, Brian Rini, W. Marston Linehan, James Finke, Jonathan M. Weiss, Kerry S. Campbell, Daniel W. McVicar
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages (TAM) contribute to cancer-related inflammation and tumor progression. While several myeloid molecules have been ascribed a regulatory function in these processes, the triggerin
Externí odkaz:
https://doaj.org/article/b29a1d769f3c4074858d8da7e828b13c
Autor:
Wei Chen, Melanie S. Nyuydzefe, Jonathan M. Weiss, Jingya Zhang, Samuel D. Waksal, Alexandra Zanin-Zhorov
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Rho-associated coiled-coil kinase (ROCK)2 targeting down-regulates autoimmune responses in animal models and patients, however the underlying molecular mechanism is still an enigma. We report that ROCK2 binds phosphorylated-STAT3 and its kin
Externí odkaz:
https://doaj.org/article/161f3b2af832421d851906abac38085c
Autor:
Christopher M. Rice, Luke C. Davies, Jeff J. Subleski, Nunziata Maio, Marieli Gonzalez-Cotto, Caroline Andrews, Nimit L. Patel, Erika M. Palmieri, Jonathan M. Weiss, Jung-Min Lee, Christina M. Annunziata, Tracey A. Rouault, Scott K. Durum, Daniel W. McVicar
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Neutrophils normally fulfil their metabolic demands by glycolysis and have limited mitochondrial activity. Here the authors show that tumours promote neutrophils adapted to oxidative mitochondria metabolism that function in the glucose-restrained tum
Externí odkaz:
https://doaj.org/article/21ee446ffa5a4d17bace3aa38b5d4bbd
Autor:
Li Yang, John C. Morris, Giorgio Trinchieri, Jonathan M. Weiss, Chi-Ping Day, Hannah H. Yan, Zhaoyang Li, Bhagelu R. Achyut, Sudheer Kumar Gara, Yanli Pang
Supplementary Figure 7 - PDF file 111K, Characterization of myeloid cells in lung, tumor, spleen, and lymph nodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157863a5d3e51e1a0b10d029b0215904
https://doi.org/10.1158/2159-8290.22530048.v1
https://doi.org/10.1158/2159-8290.22530048.v1
Autor:
Li Yang, John C. Morris, Giorgio Trinchieri, Jonathan M. Weiss, Chi-Ping Day, Hannah H. Yan, Zhaoyang Li, Bhagelu R. Achyut, Sudheer Kumar Gara, Yanli Pang
Supplementary Figure 1 - PDF file 183K, Overproduction of immature myeloid cells in both tumor bearing mice and cancer patients, flow cytometry analysis and sorting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0524093d089c7703d05db13c8f850976
https://doi.org/10.1158/2159-8290.22530069.v1
https://doi.org/10.1158/2159-8290.22530069.v1
Autor:
Li Yang, John C. Morris, Giorgio Trinchieri, Jonathan M. Weiss, Chi-Ping Day, Hannah H. Yan, Zhaoyang Li, Bhagelu R. Achyut, Sudheer Kumar Gara, Yanli Pang
Supplementary Figure 4 - PDF file 129K, Validation of over expression of TGFbeta1, IL-4, IL10, as well as Arginase1 and iNOS in Tgfbr2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5dc9610042998d1e5ee4982a5ab31b
https://doi.org/10.1158/2159-8290.22530057.v1
https://doi.org/10.1158/2159-8290.22530057.v1