Výsledky vyhledávání - "Jonathan M Warawa"

Akademický článek

Type 3 secretion system cluster 3 is a critical virulence determinant for lung-specific melioidosis.

Autor: Maria G Gutierrez, Tia L Pfeffer, Jonathan M Warawa

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 1, p e3441 (2015)

Burkholderia pseudomallei, the bacterial agent of melioidosis, causes disease through inhalation of infectious particles, and is classified as a Tier 1 Select Agent. Optical diagnostic imaging has demonstrated that murine respiratory disease models a

Externí odkaz: https://doaj.org/article/46f855bb42fe4a4d9cd346a221e8bd46

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Akademický článek

Correlation of Klebsiella pneumoniae comparative genetic analyses with virulence profiles in a murine respiratory disease model.

Autor: Ramy A Fodah, Jacob B Scott, Hok-Hei Tam, Pearlly Yan, Tia L Pfeffer, Ralf Bundschuh, Jonathan M Warawa

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107394 (2014)

Klebsiella pneumoniae is a bacterial pathogen of worldwide importance and a significant contributor to multiple disease presentations associated with both nosocomial and community acquired disease. ATCC 43816 is a well-studied K. pneumoniae strain wh

Externí odkaz: https://doaj.org/article/43545d2b930f47b1bcb4f8e8ff461121

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Akademický článek

Effective, broad spectrum control of virulent bacterial infections using cationic DNA liposome complexes combined with bacterial antigens.

Autor: Robin Ireland, Norma Olivares-Zavaleta, Jonathan M Warawa, Frank C Gherardini, Clayton Jarrett, B Joseph Hinnebusch, John T Belisle, Jeffery Fairman, Catharine M Bosio

Publikováno v: PLoS Pathogens, Vol 6, Iss 5, p e1000921 (2010)

Protection against virulent pathogens that cause acute, fatal disease is often hampered by development of microbial resistance to traditional chemotherapeutics. Further, most successful pathogens possess an array of immune evasion strategies to avoid

Externí odkaz: https://doaj.org/article/93aea17ff17e45c59cca2be8c7ad4968

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Akademický článek

Validated Preclinical Mouse Model for Therapeutic Testing against Multidrug-Resistant Pseudomonas aeruginosa Strains

Autor: Jonathan M. Warawa, Xiaoxian Duan, Charles D. Anderson, Julie B. Sotsky, Daniel E. Cramer, Tia L. Pfeffer, Haixun Guo, Scott Adcock, Alexander J. Lepak, David R. Andes, Stacey A. Slone, Arnold J. Stromberg, Jon D. Gabbard, William E. Severson, Matthew B. Lawrenz

Publikováno v: Microbiology Spectrum, Vol 10, Iss 5 (2022)

ABSTRACT The rise in infections caused by antibiotic-resistant bacteria is outpacing the development of new antibiotics. The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas ae

Externí odkaz: https://doaj.org/article/621c4d523ad043d8940f0e1b6d31b7f4

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Akademický článek

Successful Intratracheal Treatment of Phage and Antibiotic Combination Therapy of a Multi-Drug Resistant Pseudomonas aeruginosa Murine Model

Autor: Christopher Duplessis, Jonathan M. Warawa, Matthew B. Lawrenz, Matthew Henry, Biswajit Biswas

Publikováno v: Antibiotics, Vol 10, Iss 8, p 946 (2021)

Background: Pseudomonas aeruginosa (PsA) is a common etiology of bacteria-mediated lower respiratory tract infections, including pneumonia, hospital acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP). Given the paucity of novel antib

Externí odkaz: https://doaj.org/article/ab97a5dc79ee49e69f8fea61cd4f7b28

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