Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jonathan M Keith"'
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208927 (2018)
Time series segmentation aims to identify segment boundary points in a time series, and to determine the dynamical properties corresponding to each segment. To segment time series data, this article presents a Bayesian change-point model in which the
Externí odkaz:
https://doaj.org/article/49de844962e44146b60713c1deb33b89
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173331 (2017)
Small molecule inhibitors, such as lapatinib, are effective against breast cancer in clinical trials, but tumor cells ultimately acquire resistance to the drug. Maintaining sensitization to drug action is essential for durable growth inhibition. Rece
Externí odkaz:
https://doaj.org/article/8ad0031283a04254bb8bc1a10d87a73d
Autor:
Jonathan M Keith, Stephen L Gay
Publikováno v:
Image Analysis and Stereology, Vol 19, Iss 3, Pp 195-198 (2011)
This paper describes a new method for estimating particle volume distributions using isotropic, uniform, random (IUR) sections. An attractive feature of the method is that it makes no assumptions about the shape of the particles. Since IUR sections d
Externí odkaz:
https://doaj.org/article/98d224cf5786475db090c6c3f36d9690
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118595 (2015)
Wolbachia pipientis is an endosymbiotic bacterium that induces a wide range of effects in its insect hosts, including manipulation of reproduction and protection against pathogens. Little is known of the molecular mechanisms underlying the insect-Wol
Externí odkaz:
https://doaj.org/article/a8d84c5965ca4ad3bb17260bc6e9cdf3
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97336 (2014)
The 3' UTRs of eukaryotic genes participate in a variety of post-transcriptional (and some transcriptional) regulatory interactions. Some of these interactions are well characterised, but an undetermined number remain to be discovered. While some reg
Externí odkaz:
https://doaj.org/article/1918fd60797c4b869747077fa805b7d5
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33565 (2012)
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein specific to central nervous system (CNS) astrocytes. It has been the subject of intense interest due to its association with neurodegenerative diseases, and because of gr
Externí odkaz:
https://doaj.org/article/cfc5401563e948259b508298673091b6
Autor:
Martin Robinson, Jie Zhang, Alan M. Bond, SiXuan Guo, Gareth F. Kennedy, David J. Gavaghan, Jonathan M. Keith, Luke Gundry
Publikováno v:
Chemical Communications. 57:1855-1870
Advanced data analysis tools such as mathematical optimisation, Bayesian inference and machine learning have the capability to revolutionise the field of quantitative voltammetry. Nowadays such approaches can be implemented routinely with widely avai
Publikováno v:
Ecological Modelling. 475:110205
Autor:
Alan M. Bond, Luke Gundry, Gareth F. Kennedy, Jie Zhang, Martin Robinson, David J. Gavaghan, Jonathan M. Keith
Use of carefully designed computer supported parameterisation methods in voltammetric studies can provide highly robust and accurate methods for simultaneously quantifying the large number of parameters present in complex electrochemical reactions. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e600275119c09eb328467f39422acc43
https://doi.org/10.1002/celc.202100391
https://doi.org/10.1002/celc.202100391
Publikováno v:
NeuroImage, Vol 244, Iss, Pp 118635-(2021)
Brain function relies on a precisely coordinated and dynamic balance between the functional integration and segregation of distinct networks. Characterizing the way in which brain regions reconfigure their interactions to give rise to distinct but hi