Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Jonathan M Irish"'
Autor:
Sierra M Barone, Alberta GA Paul, Lyndsey M Muehling, Joanne A Lannigan, William W Kwok, Ronald B Turner, Judith A Woodfolk, Jonathan M Irish
Publikováno v:
eLife, Vol 10 (2021)
For an emerging disease like COVID-19, systems immunology tools may quickly identify and quantitatively characterize cells associated with disease progression or clinical response. With repeated sampling, immune monitoring creates a real-time portrai
Externí odkaz:
https://doaj.org/article/21ef1bb6d59e41a698679d22b7e99387
Autor:
Nalin Leelatian, Justine Sinnaeve, Akshitkumar M Mistry, Sierra M Barone, Asa A Brockman, Kirsten E Diggins, Allison R Greenplate, Kyle D Weaver, Reid C Thompson, Lola B Chambless, Bret C Mobley, Rebecca A Ihrie, Jonathan M Irish
Publikováno v:
eLife, Vol 9 (2020)
A goal of cancer research is to reveal cell subsets linked to continuous clinical outcomes to generate new therapeutic and biomarker hypotheses. We introduce a machine learning algorithm, Risk Assessment Population IDentification (RAPID), that is uns
Externí odkaz:
https://doaj.org/article/4b0f2febcca2420290d9f64856a5a58a
Autor:
Alan J Simmons, Amrita Banerjee, Eliot T McKinley, Cherie’ R Scurrah, Charles A Herring, Leslie S Gewin, Ryota Masuzaki, Seth J Karp, Jeffrey L Franklin, Michael J Gerdes, Jonathan M Irish, Robert J Coffey, Ken S Lau
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 8, Pp n/a-n/a (2016)
Externí odkaz:
https://doaj.org/article/1ce5770923c34fb3ace822f86f5a1119
Autor:
Alan J Simmons, Amrita Banerjee, Eliot T McKinley, Cherie' R Scurrah, Charles A Herring, Leslie S Gewin, Ryota Masuzaki, Seth J Karp, Jeffrey L Franklin, Michael J Gerdes, Jonathan M Irish, Robert J Coffey, Ken S Lau
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 10, Pp n/a-n/a (2015)
Abstract Understanding heterogeneous cellular behaviors in a complex tissue requires the evaluation of signaling networks at single‐cell resolution. However, probing signaling in epithelial tissues using cytometry‐based single‐cell analysis has
Externí odkaz:
https://doaj.org/article/5185166716ec481ca68a9341c25bd14d
Autor:
Maria-Fernanda Senosain, Yong Zou, Tatiana Novitskaya, Georgii Vasiukov, Aneri B. Balar, Dianna J. Rowe, Deon B. Doxie, Jonathan M. Lehman, Rosana Eisenberg, Fabien Maldonado, Andries Zijlstra, Sergey V. Novitskiy, Jonathan M. Irish, Pierre P. Massion
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Lung adenocarcinoma (ADC) is a heterogeneous group of tumors associated with different survival rates, even when detected at an early stage. Here, we aim to investigate whether CyTOF identifies cellular and molecular predictors of tumor beha
Externí odkaz:
https://doaj.org/article/6ab4fbb7ed444b2689b6cdcf1d62bde2
Autor:
Erin M. Wilfong, Todd Bartkowiak, Katherine N. Vowell, Camille S. Westlake, Jonathan M. Irish, Peggy L. Kendall, Leslie J. Crofford, Rachel H. Bonami
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The idiopathic inflammatory myopathies (IIM) are a rare clinically heterogeneous group of conditions affecting the skin, muscle, joint, and lung in various combinations. While myositis specific autoantibodies are well described, we postulate that bro
Externí odkaz:
https://doaj.org/article/a5d1bd4e467f4ee99deded0e6ec3f6eb
Autor:
Simon Le Gallou, Faustine Lhomme, Jonathan M. Irish, Anna Mingam, Celine Pangault, Celine Monvoisin, Juliette Ferrant, Imane Azzaoui, Delphine Rossille, Krimo Bouabdallah, Gandhi Damaj, Guillaume Cartron, Pascal Godmer, Steven Le Gouill, René-Olivier Casasnovas, Thierry Jo Molina, Roch Houot, Thierry Lamy, Karin Tarte, Thierry Fest, Mikael Roussel
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Absolute count of circulating monocytes has been proposed as an independent prognostic factor in diffuse large B-cell lymphoma (DLBCL). However, monocyte nomenclature includes various subsets with pro-, anti-inflammatory, or suppressive functions, an
Externí odkaz:
https://doaj.org/article/fb775c7c5eb446dba1369cb01bda5fbe
Autor:
Matthew R. Alexander, Bethany L. Dale, Charles D. Smart, Fernando Elijovich, Cara E. Wogsland, Sierra M. Lima, Jonathan M. Irish, Meena S. Madhur
Publikováno v:
JACC Basic Transl Sci
Evidence from nonhuman animal models demonstrates an important role for immune cells in hypertension, but immune cell changes in human hypertension are less clear. Using mass cytometry, we demonstrate novel and selective reductions in CCR10(+) regula
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
The monocyte/macrophage lineage has been shown to be involved in the promotion of a protumoral tumor microenvironment and resistance to treatment in B cell lymphomas. However, it is still poorly described at the single cell level, and tissue samples
Externí odkaz:
https://doaj.org/article/b6e1f42a9237498cbf46f3975209e850
Publikováno v:
Seminars in Immunopathology. 45:3-16