Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jonathan M Hazlehurst"'
Autor:
Gregory Knowles, Emily Warmington, Lisa M Shepherd, Jonathan M Hazlehurst, Anne de Bray, Helena Gleeson, Wiebke Arlt, Alessandro Prete
Publikováno v:
Endocrine Connections, Vol 12, Iss 8, Pp 1-10 (2023)
Objective: Patients with primary adrenal insufficiency (PAI) are thought to be particularly vulnerable to coronavirus disease 2019 (COVID-19); however, little is known about its true impact on this group. We assessed morbidity and health promotion at
Externí odkaz:
https://doaj.org/article/6a82c689fcde4498bef61cb918566424
Autor:
Kristien Boelaert, Keith R Abrams, Barbara Torlinska, Jonathan M Hazlehurst, Julia R Priestley, Samuel J Finnikin
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/2cd6dcbbdb0f46719df000bf59fb1c24
Autor:
Charlie Foster, Tracy Roberts, Stamatina Iliodromiti, Lucilla Poston, Shakila Thangaratinam, Helena J Teede, John Allotey, Dyuti Coomar, Nicola Heslehurst, Graham A Hitman, Jonathan M Hazlehurst, Frances Austin, Ngawai Moss, Sharon A Simpson
Publikováno v:
BMJ Open, Vol 11, Iss 6 (2021)
Introduction Mothers with gestational diabetes mellitus (GDM) are at increased risk of pregnancy-related complications and developing type 2 diabetes after delivery. Diet and physical activity-based interventions may prevent GDM, but variations in po
Externí odkaz:
https://doaj.org/article/fc43c7e7a2f245bc8da1fede56e91e41
Autor:
Rachel K Crowley, Michael W O'Reilly, Iwona J Bujalska, Zaki K Hassan-Smith, Jonathan M Hazlehurst, Danielle R Foucault, Paul M Stewart, Jeremy W Tomlinson
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163777 (2016)
AimsThe aim of this study was to assess depot-specific expression and secretion of secreted frizzled-related protein 2 (sFRP2) by adipose tissue and its effect on adipocyte biology. We measured serum sFRP2 concentrations in 106 patients in vivo to ex
Externí odkaz:
https://doaj.org/article/9dc0174875204f2ea76af45ad0904c14
Autor:
Jonathan M. Hazlehurst, Teegan Reina Lim, Catriona Charlton, Jack J. Miller, Laura L. Gathercole, Thomas Cornfield, Nikolaos Nikolaou, Shelley E. Harris, Ahmad Moolla, Nantia Othonos, Lisa C. Heather, Thomas Marjot, Damian J. Tyler, Carolyn Carr, Leanne Hodson, Jane McKeating, Jeremy W. Tomlinson
Publikováno v:
Metabolism Open, Vol 14, Iss , Pp 100177- (2022)
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition. It is tightly associated with an adverse metabolic phenotype (including obesity and type 2 diabetes) as well as with obstructive sleep apnoea (
Externí odkaz:
https://doaj.org/article/4594b0aa997b40519a78b4393c21a3ac
Autor:
Katherine Phillips, Jonathan M. Hazlehurst, Christelle Sheppard, Srikanth Bellary, Wasim Hanif, Muhammad Ali Karamat, Francesca L. Crowe, Anna Stone, G. Neil Thomas, Javeria Peracha, Anthony Fenton, Christopher Sainsbury, Krishnarajah Nirantharakumar, Indranil Dasgupta
Publikováno v:
Diabetic Medicine.
Autor:
Laura L Gathercole, Nikolaos Nikolaou, Shelley E Harris, Anastasia Arvaniti, Toryn M Poolman, Jonathan M Hazlehurst, Denise V Kratschmar, Marijana Todorčević, Ahmad Moolla, Niall Dempster, Ryan C Pink, Michael F Saikali, Liz Bentley, Trevor M Penning, Claes Ohlsson, Carolyn L Cummins, Matti Poutanen, Alex Odermatt, Roger D Cox, Jeremy W Tomlinson
Publikováno v:
Journal of Endocrinology. 253:97-113
Steroid 5β-reductase (AKR1D1) plays important role in hepatic bile acid synthesis and glucocorticoid clearance. Bile acids and glucocorticoids are potent metabolic regulators, but whether AKR1D1 controls metabolic phenotype in vivo is unknown. Akr1d
Autor:
Barbara Torlinska, Jonathan M. Hazlehurst, Krishnarajah Nirantharakumar, Thomas G. Neil, Julia Priestley, Keith R. Abrams, Kristien Boelaert
Publikováno v:
Endocrine Abstracts.
Autor:
Michael P. Gardner, Jingya Wang, Jonathan M. Hazlehurst, Chris Sainsbury, Jacqueline Blissett, Krishnarajah Nirantharakumar, Neil Thomas, Srikanth Bellary
Publikováno v:
Diabetic medicine : a journal of the British Diabetic AssociationREFERENCES.
People with pre-diabetes are at high risk of progressing to type 2 diabetes. This progression is not well characterised by ethnicity, deprivation and age, which we describe in a large cohort of individuals with pre-diabetes.A retrospective cohort stu
Publikováno v:
Clinical endocrinology. 97(2)
Obesity exacerbates the phenotype of polycystic ovarian syndrome (PCOS) including infertility as well as reducing the efficacy and access to fertility treatments. Weight management is, therefore, a key component of treatment for women with PCOS and c