Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jonathan M Gitlin"'
Publikováno v:
British Journal of Pharmacology. 139:661-671
Vasorelaxation and hyperpolarization of endothelial cells by adenosine 5′-[β-thio]diphosphate (ADPβS) and adenosine 5′-[γ-thio]triphosphate (ATPγS) were studied in rat-isolated mesenteric artery. Effects from stimulation of P2X receptors were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::258f1a4a1dd5a65a4a3b978dc96e9e4b
https://doi.org/10.1038/sj.bjp.0705271
https://doi.org/10.1038/sj.bjp.0705271
Publikováno v:
British Journal of Pharmacology. 133:825-832
Adenosine 5'-triphosphate (ATP) has important roles in the cardiovascular system, modulating vascular tone by acting as both a vasoconstrictor and a vasodilator. The dilator function of ATP is traditionally thought to be monophasic and mediated prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34684d236f62e72aeaa9700d95c7420e
https://doi.org/10.1038/sj.bjp.0704139
https://doi.org/10.1038/sj.bjp.0704139
Publikováno v:
Journal of cardiovascular pharmacology. 60(6)
Abdominal aortic aneurysms (AAAs) are a chronic condition that often progress over years to produce a weakened aorta with increased susceptibility for rupture, and currently, there are no pharmacological treatments available to slow disease progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3aded2eb3cf4363c6359158b60dd44e
https://pubmed.ncbi.nlm.nih.gov/22967986
https://pubmed.ncbi.nlm.nih.gov/22967986
Autor:
Jonathan M. Gitlin, Linda K. Curtiss, Jonathon W. Homeister, William A. Boisvert, Joshua J. Bulgrien, Jessica Counselman, John B. Lowe
A hallmark feature of atherosclerosis is that circulating mononuclear cells adhere to the endothelium and migrate into the subendothelial space. This adhesion is mediated by molecules such as selectins that are expressed on the surfaces of both leuko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ec9bda10206febe1d1e19be4f5689f
https://europepmc.org/articles/PMC2631346/
https://europepmc.org/articles/PMC2631346/
Autor:
Jonathan M. Gitlin, Charles D. Loftin
Aims The risk of adverse cardiovascular events in humans is increased with chronic use of cyclooxygenase-2 (COX-2) inhibitors. However, the role of COX-2 in animal models of cardiovascular disease has been controversial. In humans and animal models,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7814539e012b4bd483df0e7eacdc26
https://europepmc.org/articles/PMC2639107/
https://europepmc.org/articles/PMC2639107/
Publikováno v:
Cardiovascular research. 73(1)
Objective: Abdominal aortic aneurysms (AAAs) are characterized by chronic inflammation which contributes to the remodeling and eventual weakening of the vessel wall. Increased cyclooxygenase-2 (COX-2) expression is detected in human aneurysmal tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa187be594387117baef6ebbbf0c5b8d
https://pubmed.ncbi.nlm.nih.gov/17137566
https://pubmed.ncbi.nlm.nih.gov/17137566
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 26(5)
Objective— Inflammation plays an integral role in the development of abdominal aortic aneurysms (AAAs), and the expression of cyclooxygenase (COX)-2 is increased in aneurysmal tissue compared with normal aorta. Nonsteroidal anti-inflammatory drugs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93adc33d8bc2dc2f84e72355ef135265
https://pubmed.ncbi.nlm.nih.gov/16627818
https://pubmed.ncbi.nlm.nih.gov/16627818
Publikováno v:
British journal of pharmacology. 139(3)
(1) Vasorelaxation and hyperpolarization of endothelial cells by adenosine 5'-[beta-thio]diphosphate (ADPbetaS) and adenosine 5'-[gamma-thio]triphosphate (ATPgammaS) were studied in rat-isolated mesenteric artery. Effects from stimulation of P2X rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d37ea22a111a7d196cd94c37a3600a2e
https://pubmed.ncbi.nlm.nih.gov/12788826
https://pubmed.ncbi.nlm.nih.gov/12788826
Autor:
Elaine A Sugarman, Yuval Yaron, P. Frosst, Thomas Musci, Thomas O. Crawford, Petra Kaufmann, Valerie Cwik, Alex MacKenzie, Alan R. Fleischman, R. Rodney Howell, Michele A. Lloyd-Puryear, Karla Gonye, Thomas W. Prior, Kenneth Hobby, Sharon F. Terry, Michael S. Watson, Steven Keiles, Jonathan M. Gitlin, Kenneth H. Fischbeck, Ching Wang, Tiina K. Urv, Deborah Heine
Publikováno v:
Genetics in Medicine. 12:621-622
Spinal muscular atrophy is the most common fatal hereditary disease among newborns and infants. There is as yet no effective treatment. Although a carrier test is available, currently there is disagreement among professional medical societies who pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af6c88a63feddb35df95b052983f40f
https://doi.org/10.1097/gim.0b013e3181ef6079
https://doi.org/10.1097/gim.0b013e3181ef6079
Autor:
Jonathan M. Gitlin, Charles D. Loftin
Publikováno v:
Cardiovascular Research; Feb2009, Vol. 81 Issue 2, p400-400, 1p