Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Jonathan M, Rothberg"'
Autor:
Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, TR Thurston, T. R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg
Publikováno v:
Science. 378:186-192
Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with single-molecule sensitivity. Here, we demonstrate single-molecule protein sequencing using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3367086ac787e208c4c79a68cbb83f
https://doi.org/10.1126/science.abo7651
https://doi.org/10.1126/science.abo7651
Autor:
Darius Ebrahimi-Fakhari, Afshin Saffari, Lara Wahlster, Alessia Di Nardo, Daria Turner, Tommy L. Lewis Jr., Christopher Conrad, Jonathan M. Rothberg, Jonathan O. Lipton, Stefan Kölker, Georg F. Hoffmann, Min-Joon Han, Franck Polleux, Mustafa Sahin
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1053-1070 (2016)
Tuberous sclerosis complex (TSC) is a neurodevelopmental disease caused by TSC1 or TSC2 mutations and subsequent activation of the mTORC1 kinase. Upon mTORC1 activation, anabolic metabolism, which requires mitochondria, is induced, yet at the same ti
Externí odkaz:
https://doaj.org/article/5ed8e2bf932447198481e0e69bebd50d
Autor:
Adrienne Ward, Joseph Schindler, Nils H Petersen, Rachel Beekman, Jonathan M. Rothberg, W. Taylor Kimberly, Jens Witsch, Anjali M. Prabhat, Joseph Antonios, Gordon Sze, Bradley A Cahn, Mercy H Mazurek, Charles R. Wira, Teng J. Peng, Kevin N. Sheth, E. Brian Welch, Matthew M Yuen, Lauren H Sansing, Jennifer A. Kim, David Y. Hwang, Michael Poole, Audrey C Leasure, Kevin T Gobeske, Isha R. Chavva, Nona Timario, Jill T Shah, Charles C. Matouk, Anna L. Crawford, Emily J. Gilmore, Guido J. Falcone, Ajay Malhotra, Matthew S. Rosen, Laura Sacolick
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
Radiological examination of the brain is a critical determinant of stroke care pathways. Accessible neuroimaging is essential to detect the presence of intracerebral hemorrhage (ICH). Conventional magnetic resonance imaging (MRI) operates at high mag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d602a9f8501f8b316daf7f934feb8f
https://doaj.org/article/808c89a55a424463aed8befab36c67c5
https://doaj.org/article/808c89a55a424463aed8befab36c67c5
Autor:
Prantik Kundu, Seyed Sadegh Mohseni Salehi, Bradley A. Cahn, Mercy H. Mazurek, Matthew M. Yuen, E. Brian Welch, Barbara S. Gordon-Kundu, Jo Schlemper, Gordon Sze, W. Taylor Kimberly, Jonathan M. Rothberg, Michal Sofka, Kevin N. Sheth
Background and PurposeIn stroke, timely treatment is vital for preserving neurologic function. However, decision-making in neurocritical care is hindered by limited accessibility of neuroimaging and radiological interpretation. We evaluated an artifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc7884985b6b20d4e22fba1e58fe7b4
https://doi.org/10.1101/2022.01.22.22269697
https://doi.org/10.1101/2022.01.22.22269697
Autor:
Jonathan M. Rothberg, Susan A. Alie, Tyler S. Ralston, Mcmahill Daniel Rea, Karl Thiele, Jaime S. Zahorian, Rob Schneider, Christophe Meyer, David Grosjean, Gregory Corteville, Jungwook Yang, Nevada J. Sanchez, J. R. Petrus, Chao Chen, Liewei Bao, Sebastian Schaetz, Abraham R. Neben, Bob Ryan, Lawrence W. Miller, Joe Lutsky, Kailiang Chen, John D. Martin, Matthew R. Hageman, Fife Keith G, Alex Rothberg
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Affordable hand-held ultrasound is transforming health care as a diagnostic tool with the potential to be as ubiquitous as the stethoscope. Here, we present a platform for advancing diagnostic care consisting of an ultrasound-on-chip pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c187e52d5c528671f95112bbbe75922
http://europepmc.org/articles/PMC8271708
http://europepmc.org/articles/PMC8271708
Autor:
Jonathan M. Rothberg, Lutsky Joseph, Nevada J. Sanchez, Kook Youn-Jae, Fife Keith G, Chiu Leung Kin, Jungwook Yang, Chao Chen, Tyler S. Ralston, Bob Ryan, Graham Peyton, Liewei Bao, J. R. Petrus, Mcmahill Daniel Rea, Sewook Hwang, Kailiang Chen, Hamid Soleimani
Publikováno v:
ISSCC
Point-of-care ultrasound (POCUS) is transforming healthcare worldwide as a diagnostic tool with the potential to significantly reduce the delay between symptom onset and initiation of therapy. Conventional POCUS systems are based on piezoelectric tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a50fd374b1f7ae9827cecfd5eb2084e
https://doi.org/10.1109/isscc42613.2021.9365808
https://doi.org/10.1109/isscc42613.2021.9365808
Autor:
Alexander Mellmann, Dag Harmsen, Craig A Cummings, Emily B Zentz, Shana R Leopold, Alain Rico, Karola Prior, Rafael Szczepanowski, Yongmei Ji, Wenlan Zhang, Stephen F McLaughlin, John K Henkhaus, Benjamin Leopold, Martina Bielaszewska, Rita Prager, Pius M Brzoska, Richard L Moore, Simone Guenther, Jonathan M Rothberg, Helge Karch
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22751 (2011)
An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011. Serotype O104:H4, which has not been de
Externí odkaz:
https://doaj.org/article/b9eea798d9cc4a66915690e322d6888e
Autor:
Tian Xu, Jonathan M. Rothberg, Sean Landrette, Marylens Hernandez, Meiling Zheng, Sophia Gayle, Neil Beeharry, Chris Conrad, Paul Beckett, Talya Mandelkern, Henri Lichenstein, Shawn M. Ferguson
Publikováno v:
Blood. 129:1768-1778
We identified apilimod as an antiproliferative compound by high-throughput screening of clinical-stage drugs. Apilimod exhibits exquisite specificity for phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) lipid kinase and has selective cytotoxic act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4626123dd5ff5435a602fce3acf6cba
https://doi.org/10.1182/blood-2016-09-736892
https://doi.org/10.1182/blood-2016-09-736892
Autor:
Sean Landrette, Tian Xu, Xuan Zhang, Jeff Grotzke, Neil Beeharry, Paul Beckett, Henri Lichenstein, Michael Andreeff, Peter R. Young, Bing Z. Carter, Stephanie Halene, Sophia Gayle, Jonathan M. Rothberg, Marylens Hernandez
Acute myeloid leukemias (AML) harboring a constitutively active internal tandem duplication (ITD) mutation in the FMS-like kinase tyrosine kinase (FLT3) receptor are associated with poor patient prognosis. Despite initial clinical responses to FLT3 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f15f537843aefbac50e2694a3e80ad
https://europepmc.org/articles/PMC6880894/
https://europepmc.org/articles/PMC6880894/
Autor:
Bradley A Cahn, Nils H Petersen, Joseph Schindler, Gordon Sze, Firas Kaddouh, David Y. Hwang, Jonathan M. Rothberg, Adrienne Ward, Matthew S. Rosen, Matthew M Yuen, Serena Spudich, Jennifer A. Kim, Kevin N. Sheth, Mercy H Mazurek, Kevin T Gobeske, Charles C. Matouk, Emily J. Gilmore, Guido J. Falcone, Lauren H Sansing, Jill T Shah, Jonathan M. Siner, W. Taylor Kimberly
Publikováno v:
JAMA Neurology
Importance Neuroimaging is a key step in the clinical evaluation of brain injury. Conventional magnetic resonance imaging (MRI) systems operate at high-strength magnetic fields (1.5-3 T) that require strict, access-controlled environments. Limited ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6425446491a8eab92971c4ab236117
https://doi.org/10.1001/jamaneurol.2020.3263
https://doi.org/10.1001/jamaneurol.2020.3263