Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Jonathan M, Hernandez"'
Autor:
Dana A Dominguez, Alyssa V Eade, John G Aversa, Brendan L Hagerty, Andrew M Blakely, Jeremy L Davis, Laleh G Melstrom, Jonathan M Hernandez
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e34714- (2024)
Background: Extrahepatic biliary neuroendocrine tumors (EBNETs) are rare. We aimed to characterize EBNETs including factors associated with survival. Methods: The National Cancer Database was queried for patients with EBNETs from 2004 to 2016. Patien
Externí odkaz:
https://doaj.org/article/6a64304254b6498581b173771098c397
Autor:
Sarah G. Samaranayake, Lauren A. Gamble, Cassidy Bowden, Benjamin L. Green, Amber F. Gallanis, Dilara Akbulut, Niharika Shah, Jonathan M. Hernandez, Jeremy L. Davis
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102695- (2023)
Summary: More than 90% of individuals with germline pathogenic CDH1 variants will harbor occult, microscopic foci of signet ring cell carcinomas capable of progressing to advanced diffuse-type gastric cancer. Here, we present a protocol for high viab
Externí odkaz:
https://doaj.org/article/5ea65cd8e8d9479ab4b841f8988037a9
Autor:
Amanda J. Craig, Maruhen A. Datsch Silveira, Lichun Ma, Mahler Revsine, Limin Wang, Sophia Heinrich, Zachary Rae, Allison Ruchinskas, Kimia Dadkhah, Whitney Do, Shay Behrens, Farid R. Mehrabadi, Dana A. Dominguez, Marshonna Forgues, Anuradha Budhu, Jittiporn Chaisaingmongkol, Jonathan M. Hernandez, Jeremy L. Davis, Bao Tran, Jens U. Marquardt, Mathuros Ruchirawat, Michael Kelly, Tim F. Greten, Xin W. Wang
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113446- (2023)
Summary: Primary liver cancer (PLC) consists of two main histological subtypes; hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). The role of transcription factors (TFs) in malignant hepatobiliary lineage commitment between H
Externí odkaz:
https://doaj.org/article/c7e7f7a06b594b8cba26dbb54618423b
Autor:
Lichun Ma, Sophia Heinrich, Limin Wang, Friederike L. Keggenhoff, Subreen Khatib, Marshonna Forgues, Michael Kelly, Stephen M. Hewitt, Areeba Saif, Jonathan M. Hernandez, Donna Mabry, Roman Kloeckner, Tim F. Greten, Jittiporn Chaisaingmongkol, Mathuros Ruchirawat, Jens U. Marquardt, Xin Wei Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiregion sequencing is needed to better capture the heterogeneity of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). Here, the authors analyse HCC and iCCA tumours with multiregion single-cell RNA-seq, revealing cellular
Externí odkaz:
https://doaj.org/article/f2ebde2426ee4ec09a8cd16dac1ffe6f
Autor:
Tahsin M. Khan, Emily A. Verbus, Alexander J. Rossi, Jonathan M. Hernandez, Jeremy L. Davis, Brian A. Coakley, Andrew M. Blakely
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Wild-type KIT and PDGFRA gastrointestinal stromal tumors (GIST) are rare tumors with limited treatment options. We sought to determine the clinicopathologic features of wild-type GIST and identify factors that influence overall survival (OS)
Externí odkaz:
https://doaj.org/article/0f1eb6f50f8340839f716fa3d36015e0
Autor:
Stephen M Hewitt, David E Kleiner, Tim F Greten, William D Figg, Cecilia Monge, Seth M Steinberg, Maggie Cam, Benjamin Ruf, Austin G Duffy, Jonathan M Hernandez, Changqing Xie, Yuta Myojin, Kelley Coffman, Donna Mabry Hrones, Sophie Wang, Bradford J Wood, Elliot B Levy, Israa Juburi, Bernadette Redd, Philip Homan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Oncolytic immunotherapy represents a unique therapeutic platform for the treatment of cancer. Here, we evaluated the safety and efficacy of the combination of pexastimogene devacirepvec (PexaVec) plus durvalumab (anti-programmed death liga
Externí odkaz:
https://doaj.org/article/7d02b8ba4ef24ff8856cf44022b698f1
Autor:
Andrew J. H. Sedlack, Samual J. Hatfield, Suresh Kumar, Yasuhiro Arakawa, Nitin Roper, Nai-Yun Sun, Naris Nilubol, Katja Kiseljak-Vassiliades, Chuong D. Hoang, Emily K. Bergsland, Jonathan M. Hernandez, Yves Pommier, Jaydira del Rivero
Publikováno v:
Cancers, Vol 15, Iss 11, p 2873 (2023)
Adrenocortical cancer is an aggressive endocrine malignancy with an incidence of 0.72 to 1.02 per million people/year, and a very poor prognosis with a five-year survival rate of 22%. As an orphan disease, clinical data are scarce, meaning that drug
Externí odkaz:
https://doaj.org/article/6897a709043c4babbac9aab30d3acb29
Autor:
Nikolaos Zacharakis, Lutfi M. Huq, Samantha J. Seitter, Sanghyun P. Kim, Jared J. Gartner, Sivasish Sindiri, Victoria K. Hill, Yong F. Li, Biman C. Paria, Satyajit Ray, Billel Gasmi, Chyi-chia Lee, Todd D. Prickett, Maria R. Parkhurst, Paul F. Robbins, Michelle M. Langhan, Thomas E. Shelton, Anup Y. Parikh, Shoshana T. Levi, Jonathan M. Hernandez, Chuong D. Hoang, Richard M. Sherry, James C. Yang, Steven A. Feldman, Stephanie L. Goff, Steven A. Rosenberg
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(16)
PURPOSE Metastatic breast cancer (mBrCa) is most often an incurable disease with only modest responses to available immunotherapies. This study investigates the immunogenicity of somatic mutations in breast cancer and explores the therapeutic efficac
Autor:
Benjamin L. Green, Alisa N. Blumenthaler, Lauren A. Gamble, James D. McDonald, Kristen Robinson, Maureen Connolly, Monica Epstein, Jonathan M. Hernandez, Andrew M. Blakely, Brian D. Badgwell, Jeremy L. Davis
Publikováno v:
Annals of Surgical Oncology. 30:1852-1860
Autor:
Ingred Goretti Riça, Brian A. Joughin, Martha E. Teke, Tiffany R. Emmons, Alec M. Griffith, Laura A. Cahill, Valerie M. Banner-Goodspeed, Simon C. Robson, Jonathan M. Hernandez, Brahm H. Segal, Leo E. Otterbein, Carl J. Hauser, James A. Lederer, Michael B. Yaffe
Publikováno v:
Journal of Trauma and Acute Care Surgery. 94:187-196