Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Jonathan M, Coquet"'
Autor:
Xaquin Castro Dopico, Mariia Guryleva, Marco Mandolesi, Martin Corcoran, Jonathan M Coquet, Ben Murrell, Gunilla B Karlsson Hedestam
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Objectives The caecum bridges the small and large intestine and plays a front‐line role in discriminating gastrointestinal antigens. Although dysregulated in acute and chronic conditions, the tissue is often overlooked immunologically. Met
Externí odkaz:
https://doaj.org/article/b3af460353a4443abeb7b533cc7ff58f
Autor:
Leo Hanke, Hrishikesh Das, Daniel J. Sheward, Laura Perez Vidakovics, Egon Urgard, Ainhoa Moliner-Morro, Changil Kim, Vivien Karl, Alec Pankow, Natalie L. Smith, Bartlomiej Porebski, Oscar Fernandez-Capetillo, Erdinc Sezgin, Gabriel K. Pedersen, Jonathan M. Coquet, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors isolate and characterize a bispecific monomeric nanobody that induces dimerization of SARS-CoV-2 spike trimers, neutralizes variants of concerns as well as SARS-CoV, and inhibits SARS-CoV-2 infection in mice.
Externí odkaz:
https://doaj.org/article/f14234a7e3914ec1bbba1c457db3bda6
Autor:
Banu Batyrova, Fien Luwaert, Panagiota Maravelia, Yuria Miyabayashi, Neha Vashist, Julian M. Stark, Sara Y. Soori, Christopher A. Tibbitt, Peggy Riese, Jonathan M. Coquet, Benedict J. Chambers
Publikováno v:
Immunity, Inflammation and Disease, Vol 8, Iss 1, Pp 8-23 (2020)
Abstract Introduction Innate lymphoid cells (ILCs) can provide early cytokine help against a variety of pathogens in the lungs and gastrointestinal tract. Type 2 ILC (ILC2) are comparable to T helper 2 cells found in the adaptive immune system, which
Externí odkaz:
https://doaj.org/article/c83fc59b5d884748afcdb38a2f329261
Probabilistic classification of anti‐SARS‐CoV‐2 antibody responses improves seroprevalence estimates
Autor:
Xaquin Castro Dopico, Sandra Muschiol, Nastasiya F Grinberg, Soo Aleman, Daniel J Sheward, Leo Hanke, Marcus Ahl, Linnea Vikström, Mattias Forsell, Jonathan M Coquet, Gerald McInerney, Joakim Dillner, Gordana Bogdanovic, Ben Murrell, Jan Albert, Chris Wallace, Gunilla B Karlsson Hedestam
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Objectives Population‐level measures of seropositivity are critical for understanding the epidemiology of an emerging pathogen, yet most antibody tests apply a strict cutoff for seropositivity that is not learnt in a data‐driven manner,
Externí odkaz:
https://doaj.org/article/63ab6c434ce64020a328bc187339a8d8
Autor:
Daniel J. Sheward, Marco Mandolesi, Egon Urgard, Changil Kim, Leo Hanke, Laura Perez Vidakovics, Alec Pankow, Natalie L. Smith, Xaquin Castro Dopico, Gerald M. McInerney, Jonathan M. Coquet, Gunilla B. Karlsson Hedestam, Ben Murrell
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 11, Pp 100450- (2021)
Summary: Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) with resistance to neutralizing antibodies are threatening to undermine vaccine efficacy. Vaccination and infection have led to widespread humoral immuni
Externí odkaz:
https://doaj.org/article/f6fbb94e1aa445b28a40632a0756d791
Autor:
Anet Laanesoo, Egon Urgard, Kapilraj Periyasamy, Martti Laan, Yury A. Bochkov, Alar Aab, Nathaniel Magilnick, Margus Pooga, James E. Gern, Sebastian L. Johnston, Jonathan M. Coquet, Mark P. Boldin, Jesper Wengel, Alan Altraja, Grazyna Bochenek, Bogdan Jakiela, Ana Rebane
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Rhinovirus (RV) infections are associated with asthma exacerbations. MicroRNA‐146a and microRNA‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that suppress signaling through the nuclear factor kappa B (NF‐κB) pathway and inhibit
Externí odkaz:
https://doaj.org/article/2f02d187dc6f47c59c371c23de0107ac
Autor:
Marco Mandolesi, Daniel J. Sheward, Leo Hanke, Junjie Ma, Pradeepa Pushparaj, Laura Perez Vidakovics, Changil Kim, Monika Àdori, Klara Lenart, Karin Loré, Xaquin Castro Dopico, Jonathan M. Coquet, Gerald M. McInerney, Gunilla B. Karlsson Hedestam, Ben Murrell
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 4, Pp 100252- (2021)
Summary: The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2) is a current global health emergency, and effective prophylactic vaccines are needed urgently. The spike glycoprotein of SARS-CoV-2 mediates entry into h
Externí odkaz:
https://doaj.org/article/7dc9142914f7465a886ef3bfa6172c42
Autor:
Jonathan M Coquet
Publikováno v:
Immunology & Cell Biology.
Autor:
Julian M. Stark, Jielu Liu, Christopher A. Tibbitt, Murray Christian, Junjie Ma, Anna Wintersand, Josefine Dunst, Taras Kreslavsky, Ben Murrell, Mikael Adner, Hans Grönlund, Guro Gafvelin, Jonathan M. Coquet
Publikováno v:
Allergy. 77:2987-3001
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Upon activation, naïve CD4+ T cells differentiate into a number of specialized T helper (Th) cell subsets. Th2 cells are central players in immunity to helminths and are implicated in mediating the inflammatory pathology associated with allergies. T
Externí odkaz:
https://doaj.org/article/f78417fe49f84fc2a3bb62c9a6e3b61b