Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Jonathan M, Cooper"'
Autor:
Dao Thi Huyen, Julien Reboud, Dao Thanh Quyen, Jonathan M. Cooper, Thirumalaisamy P. Velavan, Ngo Tat Trung, Le Huu Song
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-8 (2024)
Abstract Background Neisseria meningitidis can cause life-threatening meningococcal meningitis and meningococcemia. Old standard microbiological results from CSF/blood cultures are time consuming. This study aimed to combine the sensitivity of loop-m
Externí odkaz:
https://doaj.org/article/a729a03bcc60497893cacf0ff9e98438
Autor:
Natasha Edwards, Julien Reboud, Xiaoxiang Yan, Xin Guo, Jonathan M. Cooper, Jemma Wadsworth, Ryan Waters, Valerie Mioulet, Donald P. King, Andrew E. Shaw
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals responsible for economic losses that amount to >$20 billion annually. Rapid recognition of FMD cases provides vital information to guide control programmes. A
Externí odkaz:
https://doaj.org/article/a86e977612ee4cffa9311555bcdb98da
Autor:
Mengyuan Lyu, Gaolian Xu, Jian Zhou, Julien Reboud, Yili Wang, Hongli Lai, Yi Chen, Yanbing Zhou, Guiying Zhu, Jonathan M. Cooper, Binwu Ying
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract Despite its importance, the functional heterogeneity surrounding the dynamics of interactions between mycobacterium tuberculosis and human immune cells in determining host immune strength and tuberculosis (TB) outcomes, remains far from unde
Externí odkaz:
https://doaj.org/article/243beb68e2aa4760b3fe5cb23810d075
Autor:
Gaolian Xu, Hao Yang, Jiani Qiu, Julien Reboud, Linqing Zhen, Wei Ren, Hong Xu, Jonathan M. Cooper, Hongchen Gu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Rapid and facile detection of specific nucleic acid modifications could have numerous applications. Here the authors present Specific Terminal Mediated Polymerase Chain Reaction (STEM-PCR) as a generic and accessible approach, and demonstrate proof-o
Externí odkaz:
https://doaj.org/article/7eae19c80ff7465f9c676e515a53c0b9
Publikováno v:
Advanced Science, Vol 10, Iss 24, Pp n/a-n/a (2023)
Abstract Phage‐inducible chromosomal islands (PICIs) are a family of phage satellites that hijack phage components to facilitate their mobility and spread. Recently, these genetic constructs are repurposed as antibacterial drones, enabling a new to
Externí odkaz:
https://doaj.org/article/3efc2380140d48e8b9e769ac00405bf1
Autor:
Yang Liu, Filipe Pinto, Xinyi Wan, Zhugen Yang, Shuguang Peng, Mengxi Li, Jonathan M. Cooper, Zhen Xie, Christopher E. French, Baojun Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
In type II CRISPR systems, the guide RNA (gRNA) comprises a CRISPR RNA (crRNA) and a hybridized trans-acting CRISPR RNA (tracrRNA), both being essential in guided DNA targeting functions. Here the authors investigate the programmability of crRNA-trac
Externí odkaz:
https://doaj.org/article/1f2bda1d331e414c93297c37542d8e4a
Autor:
Gaolian Xu, Julien Reboud, Yunfei Guo, Hao Yang, Hongchen Gu, Chunhai Fan, Xiaohua Qian, Jonathan M. Cooper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Detecting nucleic acids often requires choosing between different amplification mechanisms. Here the authors present a generalisable and programmable isothermal methodology, demonstrated in clinical applications, including for multiplexed detection o
Externí odkaz:
https://doaj.org/article/0331783ada1f4cb7b18af55056fa9ac1
Autor:
Gaolian Xu, Hao Yang, Jiani Qiu, Julien Reboud, Linqing Zhen, Wei Ren, Hong Xu, Jonathan M. Cooper, Hongchen Gu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/9e18b60f0e2f4eaeb9dea974e27ff748
Autor:
Weronika Witkowska McConnell, Chris Davis, Suleman R. Sabir, Alice Garrett, Amanda Bradley-Stewart, Pawel Jajesniak, Julien Reboud, Gaolian Xu, Zhugen Yang, Rory Gunson, Emma C. Thomson, Jonathan M. Cooper
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Current HCV nucleic acid-based diagnosis is largely performed in centralised laboratories. Here, the authors present a pan-genotypic RNA assay, based on reverse transcriptase loop mediated isothermal amplification and develop a low-cost prototype pap
Externí odkaz:
https://doaj.org/article/70d48ed159ba44c5ab33a8ce3a115976
Publikováno v:
IEEE Access, Vol 8, Pp 62905-62911 (2020)
Spatially offset Raman spectroscopy (SORS) offers the prospect of collecting spectral information detailing the molecular composition of biomaterials at greater depths below the surface layers than are normally probed by conventional Raman spectrosco
Externí odkaz:
https://doaj.org/article/d5fa955bd7764c00b09f5d0691c5cc34