Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jonathan Lucchesi"'
Autor:
Jeffrey S. Boyles, Dorota Sadowski, Scott Potter, Aleksandra Vukojicic, James Parker, William Y. Chang, Yanfei L. Ma, Mark G. Chambers, James Nelson, Barbra Barmettler, Eric M. Smith, Kara Kersjes, Evan R. Himes, Chaohua Lin, Jonathan Lucchesi, Jaladhi Brahmbhatt, Ramtin Sina, Jennifer A. Martin, Evan Maestri, Christopher M. Wiethoff, Gregory L. Dyas, Matthew D. Linnik, Songqing Na, Derrick R. Witcher, Alison Budelsky, Kira Rubtsova
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
B cells contribute to multiple aspects of autoimmune disorders, and B cell–targeting therapies, including B cell depletion, have been proven to be efficacious in treatment of multiple autoimmune diseases. However, the development of novel therapies
Externí odkaz:
https://doaj.org/article/71aa2cc4be704328879505e403536058
Autor:
Rosamund C Smith, Martin S Cramer, Pamela J Mitchell, Jonathan Lucchesi, Alicia M Ortega, Eric W Livingston, Darryl Ballard, Ling Zhang, Jeff Hanson, Kenneth Barton, Shawn Berens, Kelly M Credille, Ted A Bateman, Virginia L Ferguson, Yanfei L Ma, Louis S Stodieck
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230818 (2020)
The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice w
Externí odkaz:
https://doaj.org/article/decc66a177f0408f8026fd6a168de5b9
Autor:
Armando R Irizarry, Guirui Yan, Qingqiang Zeng, Jonathan Lucchesi, Matthew J Hamang, Yanfei L Ma, James Xiaojun Rong
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175465 (2017)
There has been growing recognition of the essential roles of citrate in biomechanical properties of mineralized tissues, including teeth and bone. However, the sources of citrate in these tissues have not been well defined, and the contribution of ci
Externí odkaz:
https://doaj.org/article/cf9bb4ef795f4db9b7caf448ca93ccd7
Autor:
Josef G, Heuer, Catalina M, Meyer, Hana E, Baker, Andrea, Geiser, Jonathan, Lucchesi, Daniel, Xu, Matthew, Hamang, Jennifer A, Martin, Charlie, Hu, Kenneth D, Roth, Kannan, Thirunavukkarasu, Jorge, Alsina-Fernandez, Yanfei L, Ma
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 382:287-298
Urocortin-1 (UCN1) is a member of the corticotropin releasing hormone (CRH) family of peptides that acts through CRH-receptor 1 (CRHR1) and CRH-receptor 2 (CRHR2). UCN1 can induce the adrenocorticotropin hormone and downstream glucocorticoids through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e901ccde71fc1559ceeb78b57a66ba8
https://doi.org/10.1124/jpet.122.001151
https://doi.org/10.1124/jpet.122.001151
Autor:
Heather A Bullock, Hana E. Baker, Matthew J Hamang, Angela J. Okragly, Y. Linda Ma, Jonathan Lucchesi, Andrea P. Martin, Robert J. Benschop, Emily A. Pena
Publikováno v:
Cytokine. 79:66-73
Interleukin (IL)-33 is a member of the IL-1 family. IL-33 effects are mediated through its receptor, ST2 and IL-1RAcP, and its signaling induces the production of a number of pro-inflammatory mediators, including TNFα, IL-1β, IL-6, and IFN-γ. Ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd157d890590f7f760e190b5dfba072e
https://doi.org/10.1016/j.cyto.2015.12.011
https://doi.org/10.1016/j.cyto.2015.12.011
Autor:
Jeffrey C. Hanson, Alicia Ortega, Eric W. Livingston, Martin S. Cramer, Louis S. Stodieck, Kelly M. Credille, Ling Zhang, Ted A. Bateman, Darryl Ballard, Pamela Jean Mitchell, Shawn Berens, Kenneth N. Barton, Jonathan Lucchesi, Virginia L. Ferguson, Yanfei L. Ma, Rosamund C. Smith
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0230818 (2020)
PLoS ONE
PLoS ONE
The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45db99c93df28195cb62657e76541b2f
https://doi.org/10.1371/journal.pone.0230818
https://doi.org/10.1371/journal.pone.0230818
Autor:
Per Aspenberg, Mary D. Adrian, Anita Harvey, Jonathan Lucchesi, Brandon R. Macias, Matt Hamang, Stuart Kuhstoss, Fredrik Agholme, Masahiko Sato
Publikováno v:
Journal of Orthopaedic Research. 32:471-476
We compared the effect of a sclerostin antibody to that of a clinically relevant dose of parathyroid hormone (PTH) in a rat model for metaphyseal bone healing. Screws of steel or poly methyl methac ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c45aece8421d907e840f3d442cdd89
https://doi.org/10.1002/jor.22525
https://doi.org/10.1002/jor.22525
Autor:
Victor H. Obungu, Jiliang Li, Henry Uhlman Bryant, Yanfei L. Ma, Nicoletta Bivi, Mary D. Adrian, Stuart Kuhstoss, Venkatesh Krishnan, Qianqiang Zeng, Matthew J Hamang, Sarah E Raines, Jonathan Lucchesi
Publikováno v:
Bone. 97
Sclerostin antibodies increase bone mass by stimulating bone formation. However, human and animal studies show that bone formation increases transiently and returns to pre-treatment level despite ongoing antibody treatment. To understand its mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cf222c103a4f63ec4426e6430045db
https://pubmed.ncbi.nlm.nih.gov/27939957
https://pubmed.ncbi.nlm.nih.gov/27939957
Autor:
Yanfei L Ma, Qingqiang Zeng, Matthew J Hamang, Jonathan Lucchesi, James X Rong, Armando R. Irizarry, Guirui Yan
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175465 (2017)
PLoS ONE
PLoS ONE
There has been growing recognition of the essential roles of citrate in biomechanical properties of mineralized tissues, including teeth and bone. However, the sources of citrate in these tissues have not been well defined, and the contribution of ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41d6c51215a04d5e04babccb916e759
https://doi.org/10.1371/journal.pone.0175465
https://doi.org/10.1371/journal.pone.0175465
Autor:
Fredrik, Agholme, Brandon, Macias, Matt, Hamang, Jonathan, Lucchesi, Mary D, Adrian, Stuart, Kuhstoss, Anita, Harvey, Masahiko, Sato, Per, Aspenberg
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 32(3)
We compared the effect of a sclerostin antibody to that of a clinically relevant dose of parathyroid hormone (PTH) in a rat model for metaphyseal bone healing. Screws of steel or poly methyl methacrylate (PMMA) were inserted bilaterally into the prox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::232b0e5763c5a1ed8e3798d9c194b3c5
https://pubmed.ncbi.nlm.nih.gov/24243768
https://pubmed.ncbi.nlm.nih.gov/24243768