Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jonathan Lecoq"'
Autor:
Sébastien L. Degorce, Craig S. Harris, Howard A. Beeley, Rémy Morgentin, David Perkins, Jonathan Lecoq
Publikováno v:
Tetrahedron Letters. 54:788-791
The synthesis of bis(amino)-1,2,4-thiadiazoles usually relies on a four step sequence. Herein, we communicate to our knowledge the first one-pot synthesis of bis(amino)-1,2,4-thiadiazoles via a double S N Ar approach.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8a07dba1f954a086b56090efa427437
https://doi.org/10.1016/j.tetlet.2012.11.107
https://doi.org/10.1016/j.tetlet.2012.11.107
Publikováno v:
Tetrahedron. 68:534-543
The preparation of 6-aminoquinazolin-4(3H)-ones requires the use of platinum–metal group catalysis on the corresponding C-6-iodo or 6-bromo precursors. Herein, we report to our knowledge the first successful SNAr reaction directly at the unactivate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94904bce21eb2a598c2bae52ae26e8f2
https://doi.org/10.1016/j.tet.2011.11.008
https://doi.org/10.1016/j.tet.2011.11.008
Autor:
Frederic Henri Jung, Arnaud Stevenin, Sébastien L. Degorce, Patrice Koza, Jonathan Lecoq, Craig S. Harris
Publikováno v:
Tetrahedron Letters. 52:6719-6722
The synthesis of differentially-substituted 3,5-bis(arylamino)pyrazoles has not yet been documented. During our investigation, we managed to develop a novel, entirely combinatorial synthesis of 3,5-bis(arylamino)pyrazoles relying on a simple one-pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e8be7465ac56bd3d2dc2be9a27369e
https://doi.org/10.1016/j.tetlet.2011.09.150
https://doi.org/10.1016/j.tetlet.2011.09.150
Autor:
Sébastien L. Degorce, Jonathan Lecoq, Howard A. Beeley, David Perkins, Craig S. Harris, Rémy Morgentin
Publikováno v:
ChemInform. 44
The selective SNAr reaction of dichloro-1,2,4-thiadiazole with amines at the 5-position can be easily combined with a second SNAr reaction to produce unsymmetrically disubstituted 3,5-bis(amino)-1,2,4-thiadiazole libraries.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da587f8bf92f38702bf4afcdc27c4b37
https://doi.org/10.1002/chin.201322136
https://doi.org/10.1002/chin.201322136