Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jonathan L.C. Lee"'
Publikováno v:
Learn Mem
The efficacy of pharmacological disruption of fear memory reconsolidation depends on several factors, including memory strength and age. We built on previous observations that systemic treatment with the nootropic nefiracetam potentiates cued fear me
Publikováno v:
Psychopharmacology
Rationale Pharmacological targeting of memory reconsolidation is a promising therapeutic strategy for the treatment of fear memory-related disorders. However, the success of reconsolidation-based approaches depends upon the effective destabilisation
Autor:
Lei M, Jonathan L.C. Lee
The aim of this research is exploring whether eye movement can facilitate memory reconsolidation, and therefore reducing trauma-like memory. It also wants to investigate whether different types (online/in person) of study and culture (UK/China) will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b46241bbe08bac3473f4c2c66070b2d2
https://doi.org/10.31234/osf.io/5auf8
https://doi.org/10.31234/osf.io/5auf8
The efficacy of pharmacological disruption of fear memory reconsolidation depends on several factors, including memory strength and age. We built on previous observations that systemic treatment with the nootropic nefiracetam potentiates cued fear me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35802b39f2498db77d2992fa35ade679
https://doi.org/10.1101/2020.05.11.088922
https://doi.org/10.1101/2020.05.11.088922
Publikováno v:
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Reconsolidation normally functions to update and maintain memories in the long-term. However, this process can be disrupted pharmacologically to weaken memories. Exploiting such experimental amnesia to disrupt the maladaptive reward memories underpin
Publikováno v:
Trends in Cognitive Sciences. 21:531-545
The reactivation of a synaptically stored memory in the brain can make the memory transiently labile. During the time it takes for the memory to re-stabilize (reconsolidate), the memory can either be reduced by an amnesic agent or enhanced by memory
Autor:
Kai Rong Tay, Maria Wimber, Charlotte R. Flavell, Jonathan L.C. Lee, Lindsey de Freitas Cassini
Publikováno v:
The Journal of Neuroscience
Memory reconsolidation is hypothesized to be a mechanism by which memories can be updated with new information. Such updating has previously been shown to weaken memory expression or change the nature of the memory. Here we demonstrate that retrieval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e47faf45e5cfa23ee61859e2b1069a1
https://eprints.gla.ac.uk/225925/1/225925.pdf
https://eprints.gla.ac.uk/225925/1/225925.pdf
Reconsolidation is a process in which re-exposure to a reminder causes a previously acquired memory to undergo a process of destabilisation followed by subsequent restabilisation. Different molecular mechanisms have been postulated for destabilisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f237333f7570a48ca66c70ebb8ffaf6a
Publikováno v:
Behavioural Brain Research. 393:112774
Studies of memory reconsolidation of pavlovian memories have typically employed unimodal conditioned stimuli, despite the use of multimodal compound stimuli in other settings. Here we studied sign-tracking behaviour to a compound audiovisual stimulus
Autor:
Marie A. Pezze, J. Peter Voigt, Tobias Bast, Carl W. Stevenson, Florence C. Heath, Jonathan L.C. Lee, Regimantas Jurkus
Publikováno v:
Psychopharmacology
RATIONALE: Dopamine D1-like receptor signalling is involved in contextual fear conditioning, but the brain regions involved and its role in other contextual fear memory processes remain unclear. OBJECTIVES: The objective of this study was to investig