Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jonathan L. Cape"'
Autor:
Molly S. Adam, Warren K. Miller, Amanda M. Pluntze, Aaron M. Stewart, Jonathan L. Cape, Michael E. Grass, Michael M. Morgen
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1225 (2022)
Figure Legend [...]
Externí odkaz:
https://doaj.org/article/b7c9c0e9bd76420183bc32dd57079541
Autor:
Molly S. Adam, Warren K. Miller, Amanda M. Pluntze, Aaron M. Stewart, Jonathan L. Cape, Michael E. Grass, Michael M. Morgen
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 555 (2022)
Many active pharmaceutical ingredients (APIs) in the pharmaceutical pipeline require bioavailability enhancing formulations due to very low aqueous solubility. Although spray dried dispersions (SDDs) have demonstrated broad utility in enhancing the b
Externí odkaz:
https://doaj.org/article/35879db5346645a8b2f5bebbbfa85cd4
Publikováno v:
International Journal of Pharmaceutics. 636:122806
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ade49986053c763b9931c513843fa8
https://doi.org/10.1016/j.ijpharm.2023.122806
https://doi.org/10.1016/j.ijpharm.2023.122806
Autor:
Kimberly B. Shepard, Na Li, Lynne S. Taylor, Michael M. Morgen, Jonathan L. Cape, Dmitry Zemlyanov, Bharat R. Mankani
Publikováno v:
Molecular Pharmaceutics
Spray drying is widely used in the manufacturing of amorphous solid dispersion (ASD) systems due to its fast drying rate, enabling kinetic trapping of the drug in amorphous form. Spray-drying conditions, such as solvent composition, can have a profou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2bb1f0bcffc9ea3eb2e8e9cd758d8f
https://doi.org/10.1021/acs.molpharmaceut.0c00798
https://doi.org/10.1021/acs.molpharmaceut.0c00798
Autor:
David Revelli, Jonathan L. Cape, Lauren Switala, Amanda M. Pluntze, John M. Baumann, Michael Banks, Yue Zhou, Philip J. Kuehl, Kimberly B. Shepard, Julia C. Oddo, Molly S. Adam, David T. Vodak
Publikováno v:
AAPS PharmSciTech
Local delivery of biotherapeutics to the lung holds great promise for treatment of lung diseases, but development of physically stable, biologically active dry powder formulations of large molecules for inhalation has remained a challenge. Here, spra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f28cd5b4865b05b9a55ffcbc8cfe24
https://doi.org/10.1208/s12249-021-02095-7
https://doi.org/10.1208/s12249-021-02095-7
Autor:
April M. Dower, Stephanie S. Buchanan, Jonathan L. Cape, Madison L. Nelson, Joseph D. Seymour, Warren K. Miller, Amanda M. Pluntze
Publikováno v:
International journal of pharmaceutics. 589
This work aims to develop complimentary analytical tools for lipid formulation selection that offer insights into the mechanisms of in-vitro drug release for solid lipid modified release excipients. Such tools are envisioned to aide and expedite the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efccc0b098454253f0a726e1fb86f6dd
https://pubmed.ncbi.nlm.nih.gov/32871217
https://pubmed.ncbi.nlm.nih.gov/32871217
Autor:
Hans-Joachim Ziock, Steen Rasmussen, Michael S. DeClue, Joseph B. Edson, James M. Boncella, Pierre-Alain Monnard, Sarah E. Maurer, Jonathan L. Cape, Liam P. Spencer
Publikováno v:
Cape, J, Edson, J B, Spencer, L P, DeClue, M S, Ziock, H-J, Maurer, S, Rasmussen, S, Monnard, P-A & Boncella, J M 2012, ' Phototriggered DNA phosphoramidate ligation in a tandem 5´-amine deprotection / 3´-imidazole activated phosphate coupling reaction ', Bioconjugate Chemistry, vol. 23, no. 10, pp. 2014-2019 . https://doi.org/10.1021/bc300093y
We report the preparation and use of an N-methyl picolinium carbamate protecting group for applications in a phototriggered nonenzymatic DNA phosphoramidate ligation reaction. Selective 5'-amino protection of a modified 13-mer oligonucleotide is achi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e8dda3f83e1d8527bf2ac9f316f80d
https://doi.org/10.1021/bc300093y
https://doi.org/10.1021/bc300093y
Autor:
Rui-Qin Zhong, Anthony K. Burrell, Songbai Han, Hongwu Xu, Jonathan L. Cape, Tatiana V. Timofeeva, Ruqiang Zou, Donald D. Hickmott, Neil J. Henson, Yusheng Zhao, Toti E. Larson
Publikováno v:
Journal of the American Chemical Society. 132:17996-17999
A novel metal-organic replica of α-PbO(2) exhibits high capacity for capture of nerve agent surrogate.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c964c1739cbd734688ef0800c0735e9
https://doi.org/10.1021/ja101440z
https://doi.org/10.1021/ja101440z
Autor:
Jonathan L. Cape, James K. Hurst
Publikováno v:
Archives of Biochemistry and Biophysics. 484:190-196
Macrophages and neutrophils are essential elements of host cellular defense systems that function, at least in part, by generating respiration-driven oxidative toxins in response to external stimuli. In both cells, encapsulation by phagocytosis provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364072e1c48a3a01cf6cde6997419e9e
https://doi.org/10.1016/j.abb.2009.01.010
https://doi.org/10.1016/j.abb.2009.01.010
Publikováno v:
Inorganic Chemistry. 47:1753-1764
(18)O-isotope-labeling studies have led to the conclusion that there exist two major pathways for water oxidation catalyzed by dimeric ruthenium ions of the general type cis, cis-[L2Ru(III)(OH2)]2O(4+). We have proposed that both pathways involve con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1aee841fca2b656e8a67b4b6c29b52
https://doi.org/10.1021/ic700724h
https://doi.org/10.1021/ic700724h