Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jonathan L. C. Lee"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Memory destabilization and reconsolidation is hypothesized to be a fundamental mnemonic process that can underpin memory updating. Instrumental memories have been shown recently to be destabilized following a reactivation session that involves a chan
Externí odkaz:
https://doaj.org/article/751f1c271fdc4d5a92f967a0c1def10d
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Reconsolidation normally functions to update and maintain memories in the long-term. However, this process can be disrupted pharmacologically to weaken memories. Exploiting such experimental amnesia to disrupt the maladaptive reward memories underpin
Externí odkaz:
https://doaj.org/article/6975d4825e9544f495b3c021d3f04747
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0205781 (2019)
Reconsolidation is a process in which re-exposure to a reminder causes a previously acquired memory to undergo a process of destabilisation followed by subsequent restabilisation. Different molecular mechanisms have been postulated for destabilisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::f9072c08fbc15b9a17df3df56b40ecab
https://doaj.org/article/90575089e91f4014a97ca4114a8fc1a0
https://doaj.org/article/90575089e91f4014a97ca4114a8fc1a0
Publikováno v:
PLoS ONE
Reconsolidation is a process in which re-exposure to a reminder causes a previously acquired memory to undergo a process of destabilisation followed by subsequent restabilisation. Different molecular mechanisms have been postulated for destabilisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4cf8880c0ba2592fd6177abf601c9232
https://pubmed.ncbi.nlm.nih.gov/30645588
https://pubmed.ncbi.nlm.nih.gov/30645588
Publikováno v:
eNeuro
This research adds to the growing body of evidence that instrumental memories (memories of interactions with the world) undergo reconsolidation, a class of memory previously not thought to undergo reconsolidation. Furthermore, we suggest that there m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f493ab9e22053391f76a32ff6c7f3d9
https://pubmed.ncbi.nlm.nih.gov/26464973
https://pubmed.ncbi.nlm.nih.gov/26464973
Autor:
Amy Claire Reichelt, Jonathan L C Lee
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
Memory reconsolidation has been observed across species and in a number of behavioural paradigms. The majority of memory reconsolidation studies have been carried out in pavlovian fear conditioning and other aversive memory settings, with potential i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::0bce945a3df4b2e864b35a75d67c414c
http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00118/full
http://journal.frontiersin.org/Journal/10.3389/fnbeh.2013.00118/full
Publikováno v:
Discovery medicine. 4(22)
Extract: Fresh memories need time to stabilize. The idea that new long-term memories (LTM) undergo a time-dependent consolidation process after acquisition has received substantial empirical support in over a century of experimental studies. These st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d5c7d3d4a2cee89a6b7e658eff1a777
https://pubmed.ncbi.nlm.nih.gov/20704983
https://pubmed.ncbi.nlm.nih.gov/20704983
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Cannabidiol (CBD) has been established to have both acute and long-lasting effects to reduce fear memory expression. The long-lasting impact might be mediated by an enhancement of memory extinction or an impairment of memory reconsolidation. Here, we
Externí odkaz:
https://doaj.org/article/9ea0c90d575a4d1b96d61cc33f012255
Autor:
Regimantas Jurkus, Harriet Laura Lavinia Day, Francisco S. Guimaraes, Jonathan L C Lee, Leandro Jose Bertoglio, Carl W. Stevenson
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Anxiety and trauma-related disorders are psychiatric diseases with a lifetime prevalence of up to 25%. Phobias and post-traumatic stress disorder (PTSD) are characterized by abnormal and persistent memories of fear-related contexts and cues. The effe
Externí odkaz:
https://doaj.org/article/6da7ab725b284ce2a7a7b53233e3d550
Autor:
Jonathan L C Lee, Charlotte eFlavell
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
The reactivation of a memory can result in its destabilization, necessitating a process of memory reconsolidation to maintain its persistence. Here we show that the destabilization of a contextual fear memory is potentiated by the cannabinoid CB1 rec
Externí odkaz:
https://doaj.org/article/4b5a5924f40c4aa0895c2a0b5e2ca865