Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Jonathan L Bramson"'
Autor:
Olga‐Demetra Biziotis, Evangelia Evelyn Tsakiridis, Amr Ali, Elham Ahmadi, Jianhan Wu, Simon Wang, Bassem Mekhaeil, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Bassam Abdulkarim, Ranjan K. Sur, Aruz Mesci, Peter Ellis, Tobias Berg, Jonathan L Bramson, Paola Muti, Gregory R Steinberg, Theodoros Tsakiridis
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2235-2256 (2023)
Non‐small cell lung cancer (NSCLC) has a poor prognosis, and effective therapeutic strategies are lacking. The diabetes drug canagliflozin inhibits NSCLC cell proliferation and the mammalian target of rapamycin (mTOR) pathway, which mediates cell g
Externí odkaz:
https://doaj.org/article/fdf11bf69eda42b6b882eebd1bdee6ce
Autor:
Jonathan L Bramson, Arya Afsahi, Allyson E Moore, Nickolas Serniuck, Hayley Nault, Sheila K Singh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/3ab92fea536844a5a30f896fdeb34c0d
Autor:
Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159471 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0155947.].
Externí odkaz:
https://doaj.org/article/6726513060824e6e936b2c00406b88c8
Autor:
Abhirami A Ananth, Lee-Hwa Tai, Casey Lansdell, Almohanad A Alkayyal, Katherine E Baxter, Leonard Angka, Jiqing Zhang, Christiano Tanese de Souza, Kyle B Stephenson, Kelley Parato, Jonathan L Bramson, John C Bell, Brian D Lichty, Rebecca C Auer
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155947 (2016)
Anti-tumor CD8+ T cells are a key determinant for overall survival in patients following surgical resection for solid malignancies. Using a mouse model of cancer vaccination (adenovirus expressing melanoma tumor-associated antigen (TAA)-dopachrome ta
Externí odkaz:
https://doaj.org/article/551c7ca1f5e9471199f644eceec99f59
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
The use of engineered T cells in adoptive transfer therapies has shown significant promise in treating hematological cancers. However, successes treating solid tumors are much less prevalent. Oncolytic viruses (OVs) have the capacity to induce specif
Externí odkaz:
https://doaj.org/article/739b87a304b5473983ed5740c254f581
Autor:
Chris P Verschoor, Jennie Johnstone, Jamie Millar, Robin Parsons, Alina Lelic, Mark Loeb, Jonathan L Bramson, Dawn M E Bowdish
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104522 (2014)
Circulating myeloid cells are important mediators of the inflammatory response, acting as a major source of resident tissue antigen presenting cells and serum cytokines. They represent a number of distinct subpopulations whose functional capacity and
Externí odkaz:
https://doaj.org/article/c8e5de36fd724b9da067d3e765888485
Autor:
Alina Lelic, Chris P Verschoor, Mario Ventresca, Robin Parsons, Carole Evelegh, Dawn Bowdish, Michael R Betts, Mark B Loeb, Jonathan L Bramson
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003076 (2012)
As humans age, they experience a progressive loss of thymic function and a corresponding shift in the makeup of the circulating CD8+ T cell population from naïve to memory phenotype. These alterations are believed to result in impaired CD8+ T cell r
Externí odkaz:
https://doaj.org/article/78113a49ab524d1784921b895d90b156
Autor:
Paolo Piazza, Curtis P McMurtrey, Alina Lelic, Robert L Cook, Rachel Hess, Eric Yablonsky, Luann Borowski, Mark B Loeb, Jonathan L Bramson, William H Hildebrand, Charles R Rinaldo
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15343 (2010)
West Nile virus (WNV) infection can result in severe neuroinvasive disease, particularly in persons with advanced age. As rodent models demonstrate that T cells play an important role in limiting WNV infection, and strong T cell responses to WNV have
Externí odkaz:
https://doaj.org/article/a44c8b49ca0a4d189411cdb769411665
Autor:
Jessica A. Breznik, Ahmad Rahim, Tara Kajaks, Megan Hagerman, Lucas Bilaver, Karen Colwill, Roaya M. Dayam, Anne-Claude Gingras, Chris P. Verschoor, Janet E. McElhaney, Jonathan L. Bramson, Dawn M. E. Bowdish, Andrew P. Costa
Publikováno v:
Journal of the American Medical Directors Association. 24:753-758
ObjectivesTo identify factors that contribute to protection from infection with the Omicron variant of SARS-CoV-2 in older adults in nursing and retirement homes.DesignLongitudinal cohort study with retrospective analysis of infection risk.Setting an
Autor:
Ksenia Bezverbnaya, Joanne A. Hammill, Derek Cummings, Bojana Bojovic, Bella Groisman, Christopher L. Baker, Craig Aarts, Danielle L. Hayes, Donna Rill, Stacey X. Xu, Andreas G. Bader, Christopher W. Helsen, Jonathan L. Bramson
Publikováno v:
Cytotherapy. 25:490-501