Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jonathan L, Golob"'
Autor:
Samuel S. Minot, Bailey Garb, Alennie Roldan, Alice S. Tang, Tomiko T. Oskotsky, Christopher Rosenthal, Noah G. Hoffman, Marina Sirota, Jonathan L. Golob
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 11, Pp 100639- (2023)
Summary: For studies using microbiome data, the ability to robustly combine data from technically and biologically distinct microbiome studies is a crucial means of supporting more robust and clinically relevant inferences. Formidable technical chall
Externí odkaz:
https://doaj.org/article/d426c1221d534a3dae28101d093db1fc
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Researchers must be able to generate experimentally testable hypotheses from sequencing-based observational microbiome experiments to discover the mechanisms underlying the influence of gut microbes on human health. We describe geneshot, a n
Externí odkaz:
https://doaj.org/article/b32b0dda71424fefae1e0642ce533a53
Autor:
Jin Imai, Hitoshi Ichikawa, Sho Kitamoto, Jonathan L. Golob, Motoki Kaneko, Junko Nagata, Miho Takahashi, Merritt G. Gillilland III, Rika Tanaka, Hiroko Nagao-Kitamoto, Atsushi Hayashi, Kohei Sugihara, Shrinivas Bishu, Shingo Tsuda, Hiroyuki Ito, Seiichiro Kojima, Kazunari Karakida, Masashi Matsushima, Takayoshi Suzuki, Katsuto Hozumi, Norihito Watanabe, William V. Giannobile, Takayuki Shirai, Hidekazu Suzuki, Nobuhiko Kamada
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Oral conditions are relatively common in patients with inflammatory bowel disease (IBD). However, the contribution of oral maladies to gut inflammation remains unexplored. Here, we investigated the effect of periodontitis on disease phenotypes of pat
Externí odkaz:
https://doaj.org/article/6805a612c28d497eaa0707b7c8d4ff9f
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Roughly 1 year after the first case of COVID-19 was identified and less than 1 year after the sequencing of SARS-CoV-2, multiple SARS-CoV-2 vaccines with demonstrated safety and efficacy in phase III clinical trials are available. The most promising
Externí odkaz:
https://doaj.org/article/401cdf38fdb14bafb36103a60ab91e45
Autor:
Jonathan L. Golob, Martha M. DeMeules, Tillie Loeffelholz, Z.Z. Quinn, Michael K. Dame, Sabrina S. Silvestri, Michael C. Wu, Thomas M. Schmidt, Tina L. Fiedler, Matthew J. Hoostal, Marco Mielcarek, Jason Spence, Steven A. Pergam, David N. Fredricks
Publikováno v:
Blood Advances, Vol 3, Iss 19, Pp 2866-2869 (2019)
Externí odkaz:
https://doaj.org/article/69ffd6300fdd45849caedb6922866691
Autor:
Michael E. Bowdish, Christina E. Barkauskas, Jessica R. Overbey, Robert L. Gottlieb, Keren Osman, Abhijit Duggal, Mary E. Marks, Jonathan Hupf, Eustace Fernandes, Bradley G. Leshnower, Jonathan L. Golob, Alexander Iribarne, Athos J. Rassias, Ellen G. Moquete, Karen O’Sullivan, Helena L. Chang, Judson B. Williams, Sam Parnia, Nirav C. Patel, Nimesh D. Desai, Andrew M. Vekstein, Beth A. Hollister, Tammie Possemato, Christian Romero, Peter C. Hou, Elizabeth Burke, Jack Hayes, Fred Grossman, Silviu Itescu, Marc Gillinov, Francis D. Pagani, Patrick T. O’Gara, Michael J. Mack, Peter K. Smith, Emilia Bagiella, Alan J. Moskowitz, Annetine C. Gelijns
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:261-270
Autor:
Jonathan L. Golob
Publikováno v:
Annual Review of Biomedical Data Science. 6
The human microbiome is complex, variable from person to person, essential for health, and related to both the risk for disease and the efficacy of our treatments. There are robust techniques to describe microbiota with high-throughput sequencing, an
Publikováno v:
Viruses, Vol 13, Iss 6, p 1059 (2021)
Acute gastroenteritis (AGE) has a significant disease burden on society. Noroviruses, rotaviruses, and astroviruses are important viral causes of AGE but are relatively understudied enteric pathogens. Recent developments in novel biomimetic human mod
Externí odkaz:
https://doaj.org/article/f4584369b0494c01a6d83c1ea3fa5f65
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Microbiome studies commonly use 16S rRNA gene amplicon sequencing to characterize microbial communities. Errors introduced at multiple steps in this process can affect the interpretation of the data. Here we evaluate the accuracy
Externí odkaz:
https://doaj.org/article/7330e6e9d7a44eaeba9da5da3cc49852
Autor:
Emma Lauder, Jonathan L Golob
Publikováno v:
Open Forum Infectious Diseases. 9
Background Human Herpes Virus 7 (HHV7) infection results in a lifelong latent infection with over 95% of adults seropositive for HHV7. Lymphocytes are the best understood host cell type for latent HHV7, with the gastric mucosa another site of latent