1147 mRNAs encoding an innate immune receptor enhance the immunogenicity of lipid nanoparticle vaccines

Autor: Dania Zhivaki, Emily Gosselin, Holly Concepcion, Caitlin Sullivan, Jonathan Chow, Debrup Sengupta, Anastasia Nikiforov, Chisom Arinze, Jonathan Kagan

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/5204c0e9139d4b169168c84759a3b609

Excess lipids on endosomes dictate NLRP3 localization and inflammasome activation

Autor: Jonathan Kagan

Publikováno v: Nature Immunology. 24:3-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::390282ff651230f89d33e80e40d8057a
https://doi.org/10.1038/s41590-022-01364-2

Social Mobilization for Ebola Virus Clinical Trials During a Public Health Crisis in Liberia.

Autor: *, Jonathan Kagan

Publikováno v: Progress in Community Health Partnerships; Fall2021, Vol. 15 Issue 3, p1-12, 12p

Increasing value and reducing waste in biomedical research regulation and management

Autor: Iain Chalmers, Jonathan Kagan, Malcolm R. Macleod, Elaine Beller, Rustam Al-Shahi Salman, Julian Savulescu, Robert S. Phillips, Elina Hemminki, Janet Wisely

Publikováno v: Al-Shahi Salman, R, Beller, E, Kagan, J, Hemminki, E, Phillips, R S, Savulescu, J, Macleod, M, Wisely, J & Chalmers, I 2014, ' Increasing value and reducing waste in biomedical research regulation and management ', The Lancet, vol. 383, no. 9912, pp. 176-85 . https://doi.org/10.1016/S0140-6736(13)62297-7

Summary After identification of an important research question and selection of an appropriate study design, waste can arise from the regulation, governance, and management of biomedical research. Obtaining regulatory and governance approval has beco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6104a0522dc81e9b157bb18c16350bf8
https://europepmc.org/articles/PMC3952153/

MyD88-dependent TLR signals are necessary and sufficient to confer dendritic cells with gut-specific imprinting properties. (161.2)

Autor: Sen Wang, Eduardo Villablanca, Daniel Gomes, Deanna Nguyen, Emiko Mizoguchi, Jonathan Kagan, Hans-Christian Reinecker, Nir Hacohen, Cathryn Nagler, Ramnik Xavier, Bartira Rossi-Bergmann, Yi-Bin Chen, Rune Blomhoff, Scott Snapper, Rodrigo Mora

Publikováno v: The Journal of Immunology. 186:161.2-161.2

Lymphocyte migration is at the heart of normal and pathological immune responses in the intestinal mucosa. We and others have shown that, in addition to activating lymphocytes, gut-associated dendritic cells (GALT-DC) can metabolize dietary vitamin A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::537d274b6a33fbb0f02c650c3b56bdac
https://doi.org/10.4049/jimmunol.186.supp.161.2