Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jonathan K. Williams"'
Autor:
Peng Dai, Jonathan K. Williams, Chi Zhang, Matthew Welborn, James J. Shepherd, Tianyu Zhu, Troy Van Voorhis, Mei Hong, Bradley L. Pentelute
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Natural enzymes use local environments to tune the reactivity of amino acid side chains. In searching for small peptides with similar properties, we discovered a four-residue π-clamp motif (Phe-Cys-Pro-Phe) for regio- and chemoselective ary
Externí odkaz:
https://doaj.org/article/65ff2ecec9fc40949a8979455dbaebf8
Publikováno v:
Protein Science. 32
Fibrillar collagen-integrin interactions in the extracellular matrix (ECM) regulate a multitude of cellular processes and cell signalling. Collagen I fibrils serve as the molecular scaffolding for connective tissues throughout the human body and are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b0e31195bcecfacd7c5b2215d3f943
https://doi.org/10.1002/pro.4508
https://doi.org/10.1002/pro.4508
Autor:
Charlotte Labrie-Cleary, Jitendra Singh, Steven Arnold, Andrew Sam, Mark Dresel, Luz Helena Alfaro Alvarado, Rebecca Roberts, Emily Fingar, Jennifer Jiang, Paul Craig, Jean Baum, Eddy Arnold, Christine Zardecki, Grace Brannigan, Julia R. Koeppe, Elizabeth M Hennen, Alan Trudeau, Joseph H Lubin, Thejasvi Venkatachalam, Jonathan K. Williams, Kevin Catalfano, Stephen K. Burley, Brian P. Hudson, Isaac Paredes, Sagar D. Khare, Yana Bromberg, Katherine See, Evan Lenkeit, Shuchismita Dutta, J. Steen Hoyer, Erika McCarthy, Michael J. Pikaart, Santiago Soto Zapata, Jenna Currier, Stephanie Laporte, Jay A. Tischfield, Siobain Duffy, Britney Dyszel, Maria Voigt, Changpeng Lu, Bonnie L. Hall, Jesse Sandberg, Kailey Martin, Aaliyah Khan, Stephen A. Mills, Sophia Staggers, Allison Rupert, Elliott M Dolan, Vidur Sarma, Lindsey Whitmore, Helen Zheng, Ashish Duvvuru, David S. Goodsell, Michael Kirsch, Melanie Ortiz-Alvarez de la Campa, Ali A Khan, Matthew Benedek, Francesc X. Ruiz, John D. Westbrook, Marilyn Orellana, Lingjun Xie, Zhuofan Shen, Baleigh Wheeler, Brea Tinsley
Publikováno v:
Proteins
bioRxiv
bioRxiv
Three-dimensional structures of SARS-CoV-2 and other coronaviral proteins archived in the Protein Data Bank were used to analyze viral proteome evolution during the first six months of the COVID-19 pandemic. Analyses of spatial locations, chemical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184f799ef7472866dc4aa3149ef49eaf
https://doi.org/10.1002/prot.26250
https://doi.org/10.1002/prot.26250
Publikováno v:
Proteins
Since the identification of the SARS‐CoV‐2 virus as the causative agent of the current COVID‐19 pandemic, considerable effort has been spent characterizing the interaction between the Spike protein receptor‐binding domain (RBD) and the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e136e51cdb3c00c7908555c395b0862
http://europepmc.org/articles/PMC8441656
http://europepmc.org/articles/PMC8441656
α-Synuclein (αS) is an intrinsically disordered protein (IDP) that aggregates into amyloid fibrils during the progression of Parkinson's Disease and other synucleinopathies. The N-terminal domain (residues 1-60) is now understood to play a critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68df7db55e60dc764442f6aaa019a691
https://doi.org/10.1101/2021.05.26.445860
https://doi.org/10.1101/2021.05.26.445860
Publikováno v:
Proc Natl Acad Sci U S A
Amyloid fibril formation of α-synuclein (αS) is associated with multiple neurodegenerative diseases, including Parkinson’s Disease (PD). Growing evidence suggests that progression of PD is linked to cell-to-cell propagation of αS fibrils, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15defedd123dabaf73db2e4a8bb17d3c
https://doi.org/10.1073/pnas.2017452118
https://doi.org/10.1073/pnas.2017452118
Since the identification of the SARS-CoV-2 virus as the causative agent of the current COVID-19 pandemic, considerable effort has been spent characterizing the interaction between the Spike protein receptor-binding domain (RBD) and the human angioten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3412f323594cda7961baf68d30aac3
https://doi.org/10.1101/2021.01.08.425965
https://doi.org/10.1101/2021.01.08.425965
Collagen fibrils serve as the molecular scaffolding for connective tissues throughout the human body and are the most abundant protein building blocks in the extracellular matrix (ECM). Glycosaminoglycans (GAGs) are an important class of polysacchari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4010d573a003f1ea89f06d73ce7b4ca
https://doi.org/10.1101/2020.02.07.935932
https://doi.org/10.1101/2020.02.07.935932
Publikováno v:
Journal of Molecular Biology. 430:2360-2371
The intrinsically disordered protein β-synuclein is known to inhibit the aggregation of its intrinsically disordered homolog, α-synuclein, which is implicated in Parkinson's disease. While β-synuclein itself does not form fibrils at the cytoplasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9ad8f77631570d1e1ae207d0e4a84f
https://doi.org/10.1016/j.jmb.2018.05.024
https://doi.org/10.1016/j.jmb.2018.05.024
Autor:
Chi Zhang, Troy Van Voorhis, Bradley L. Pentelute, Jonathan K. Williams, Tianyu Zhu, James J. Shepherd, Mei Hong, Peng Dai, Matthew Welborn
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Natural enzymes use local environments to tune the reactivity of amino acid side chains. In searching for small peptides with similar properties, we discovered a four-residue π-clamp motif (Phe-Cys-Pro-Phe) for regio- and chemoselective arylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f22b929170102a4b50c09045097953
https://doaj.org/article/65ff2ecec9fc40949a8979455dbaebf8
https://doaj.org/article/65ff2ecec9fc40949a8979455dbaebf8