Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Jonathan K. Stiles"'
Autor:
Cecilia Elorm Lekpor, Felix Botchway, Kwadwo Asamoah Kusi, Andrew A. Adjei, Michael D. Wilson, Jonathan K. Stiles, Nana O. Wilson
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Malaria related mortality is associated with significant deregulation of host inflammatory factors such as interferon-inducible protein 10, a member of the CXC or α-subfamily (CXCL10), and host angiogenic factors such as angiopoi
Externí odkaz:
https://doaj.org/article/48cc2e0f37c5409b86f0aadee0fac045
Autor:
Justin J. Thomas, Keri Oxendine Harp, Alaijah Bashi, Joshua L. Hood, Felix Botchway, Michael D. Wilson, Winston E. Thompson, Jonathan K. Stiles, Adel Driss
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hemolysis is associated with many pathologies, including trauma, sepsis, hemorrhagic stroke, malaria, and genetic disorders such as sickle cell disease (SCD). When hemolysis occurs, free-heme drives vascular inflammation, resulting in oxidative tissu
Externí odkaz:
https://doaj.org/article/e8c37e4f126b4229a63da5b737918a56
Autor:
Adriana Harbuzariu, Annette Nti, Keri Oxendine Harp, Juan C. Cespedes, Adel Driss, Jonathan K. Stiles
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104407- (2022)
Summary: Human cerebral malaria (HCM) is a severe complication of Plasmodium falciparum (P.f.) infection that is characterized by capillary occlusions, rupture of the blood-brain barrier (BBB), perivascular cellular injury, and brain swelling. P.f.hi
Externí odkaz:
https://doaj.org/article/614beb3c118f4e97a27a715fe28270a5
Autor:
Keri Oxendine Harp, Felix Botchway, Yvonne Dei-Adomakoh, Michael D. Wilson, Mohamed Mubasher, Andrew A. Adjei, Winston E. Thompson, Jonathan K. Stiles, Adel Driss
Publikováno v:
EClinicalMedicine, Vol 39, Iss , Pp 101045- (2021)
Background: Sickle cell anemia (SCA) is a severe monogenic disorder, caused by single nucleotide mutations in the hemoglobin (Hb) gene, that is prevalent in malaria endemic regions of the world. Sickle cell trait (SCT) individuals carry only one of t
Externí odkaz:
https://doaj.org/article/4a6811c384ed4a8c988f1a1a159402f8
Autor:
Christopher Chambliss, Tatayana Richardson, John Onyekaba, Juan Cespedes, Annette Nti, Keri Oxendine Harp, Iris Buchanan-Perry, Jonathan K. Stiles, Beatrice E. Gee
Publikováno v:
Endocrine and Metabolic Science, Vol 3, Iss , Pp 100088- (2021)
ABSTRACT: Stroke, or cerebral infarction, is one of the most serious complications of sickle cell anemia (SCA) in childhood, potentially leading to impaired development and life-long physical and cognitive disabilities. About one in ten children with
Externí odkaz:
https://doaj.org/article/c8fd888f066c4a0ea969398e6965fd8c
Autor:
Keri Oxendine Harp, Felix Botchway, Yvonne Dei-Adomakoh, Michael D. Wilson, Joshua L. Hood, Andrew A. Adjei, Jonathan K. Stiles, Adel Driss
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In 2018, 228 million cases and 405,000 malaria-associated deaths were reported worldwide with a majority being in Africa. A wide range of factors, including parasitemia, host immunity, inflammatory responses to infection, and host hemoglobin genotype
Externí odkaz:
https://doaj.org/article/8ff6d80ac58d4010bc679e1f43218877
Autor:
Lambert Tetteh Appiah, Fred Stephen Sarfo, Samuel Blay Nguah, Mark D. Huffman, Jonathan K. Stiles, Matthew J. Feinstein
Publikováno v:
Global Heart, Vol 15, Iss 1 (2020)
Background: Lipoprotein(a) [Lp(a)] and high-sensitivity C-reactive protein (hs-CRP) levels are associated with cardiovascular disease (CVD) in the general population, even after adjusting for conventional CVD risk factors. However, data are limited r
Externí odkaz:
https://doaj.org/article/ada37d88c9634c268bbacb9568f296a5
Autor:
Juan Carlos Cespedes, Jacqueline Hibbert, Sri Krishna, Fengxia Yan, Praveen K. Bharti, Jonathan K. Stiles, Mingli Liu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundCerebral malaria (CM) is characterized by the sequestration of Plasmodium-infected erythrocytes (pRBCs) to host brain microvasculature beds via P. falciparum erythrocyte membrane protein 1 (PfEMP1). Under normal conditions, activated protei
Externí odkaz:
https://doaj.org/article/5327c0e91c7d46de96fa6772bb40166d
Autor:
Mingli Liu, Wesley Solomon, Juan Carlos Cespedes, Nana O. Wilson, Byron Ford, Jonathan K. Stiles
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-15 (2018)
Abstract Background Human cerebral malaria (HCM) is a severe form of malaria characterized by sequestration of infected erythrocytes (IRBCs) in brain microvessels, increased levels of circulating free heme and pro-inflammatory cytokines and chemokine
Externí odkaz:
https://doaj.org/article/53453936245d4108a72748a19512b396
Autor:
Mohamed Mubasher, Thomas Pearson, Muhammed Y. Idris, Kimberly Lawson, Jada Holmes, Priscilla Pemu, Adriana Baez, Jonathan K. Stiles, Maritza S. Salazar, Winston E. Thompson, Alexander Quarshie, Lee S. Caplan, Yulia Strekalova, Elizabeth Ofili
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 20; Issue 9; Pages: 5738
The National Research Mentoring Network (NRMN) Strategic Empowerment Tailored for Health Equity Investigators (SETH) study evaluates the value of adding Developmental Network to Coaching in the career advancement of diverse Early-Stage Investigators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0da177da0ac8074dce23780dff43f4