Novel structural components of the ventral disc and lateral crest in Giardia intestinalis.

Autor: Kari D Hagen, Matthew P Hirakawa, Susan A House, Cindi L Schwartz, Jonathan K Pham, Michael J Cipriano, Moises J De La Torre, Albert C Sek, Gary Du, Brystal M Forsythe, Scott C Dawson

Publikováno v: PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1442 (2011)

Giardia intestinalis is a ubiquitous parasitic protist that is the causative agent of giardiasis, one of the most common protozoan diarrheal diseases in the world. Giardia trophozoites attach to the intestinal epithelium using a specialized and elabo

Externí odkaz: https://doaj.org/article/63837b4b15dd4967893aefd3819d275b

Transcriptomic profiling of high-density Giardia foci encysting in the murine proximal intestine

Autor: Jonathan K Pham, Kari D. Hagen, Christopher Nosala, Hannah N. Starcevich, Kristofer Nguyen, Erica Y. Scott, Scott C. Dawson

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)

Giardiais a highly prevalent, understudied protistan parasite causing significant diarrheal disease worldwide. Its life cycle consists of two stages: infectious cysts ingested from contaminated food or water sources, and motile trophozoites that colo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918991cb38b9c8649a7c74a5d34624b3

Giardia colonizes and encysts in high density foci in the murine small intestine

Autor: Stéphane Gourguechon, Nanelle Barash, Christopher Nosala, Brendan McCarthy-Sinclair, Jonathan K Pham, Shane G McInally, Scott C. Dawson

Giardiais a highly prevalent, yet understudied protistan parasite causing diarrheal disease worldwide. Hosts ingestGiardiacysts from contaminated sources. In the gastrointestinal tract, cysts excyst to become motile trophozoites, colonizing and attac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d07afb4213635255c82bffd6b5d0b7a4
https://doi.org/10.1101/080226

Novel structural components of the ventral disc and lateral crest in Giardia intestinalis

Autor: Brystal M. Forsythe, Cindi L. Schwartz, Susan A. House, Jonathan K Pham, Scott C. Dawson, Michael J. Cipriano, Kari D. Hagen, Gary Du, Moises J. De La Torre, Matthew P. Hirakawa, Albert C. Sek

Publikováno v: PLoS neglected tropical diseases, vol 5, iss 12
PLoS Neglected Tropical Diseases, Vol 5, Iss 12, p e1442 (2011)
PLoS Neglected Tropical Diseases

Giardia intestinalis is a ubiquitous parasitic protist that is the causative agent of giardiasis, one of the most common protozoan diarrheal diseases in the world. Giardia trophozoites attach to the intestinal epithelium using a specialized and elabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1608f3a93465bc31c165f63b3e90043
https://escholarship.org/uc/item/6gn71044

High-resolution crystal structure and in vivo function of a kinesin-2 homologue in Giardia intestinalis

Autor: Scott C. Dawson, Jan Löwe, J. C. Hoeng, Joel Mancuso, Jonathan K Pham, Meredith Sagolla, Susan A. House, W Z Cande

Publikováno v: Molecular biology of the cell. 19(7)

A critical component of flagellar assembly, the kinesin-2 heterotrimeric complex powers the anterograde movement of proteinaceous rafts along the outer doublet of axonemes in intraflagellar transport (IFT). We present the first high-resolution struct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8688af17bcfe40a5f41962262960164b
https://pubmed.ncbi.nlm.nih.gov/18463165