Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jonathan J. Hernandez"'
Autor:
Jonathan J. Hernandez, Doyle E. Beaty, Logan L. Fruhwirth, Ana P. Lopes Chaves, Neil H. Riordan
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from
Externí odkaz:
https://doaj.org/article/3492954afc4c45588e408ac2af1ac1b4
Autor:
Yuriy V. Egorov, Di Lang, Leonid Tyan, Daniel Turner, Evi Lim, Zachary D. Piro, Jonathan J. Hernandez, Rylie Lodin, Rose Wang, Eric G. Schmuck, Amish N. Raval, Carter J. Ralphe, Timothy J. Kamp, Leonid V. Rosenshtraukh, Alexey V. Glukhov
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 20 (2019)
Background Atrial fibrillation often occurs in the setting of hypertension and associated atrial dilation with pathologically increased cardiomyocyte stretch. In the setting of atrial dilation, mechanoelectric feedback has been linked to the developm
Externí odkaz:
https://doaj.org/article/f0cffe821e2a46e59e63602870d31e8b
Autor:
Jingjing Zheng, Holly C. Dooge, Marta Pérez-Hernández, Yan-Ting Zhao, Xi Chen, Jonathan J. Hernandez, Carmen R. Valdivia, Julieta Palomeque, Eli Rothenberg, Mario Delmar, Héctor H. Valdivia, Francisco J. Alvarado
Publikováno v:
J Mol Cell Cardiol
Ryanodine receptor 2 (RyR2) is an ion channel in the heart responsible for releasing into the cytosol most of the Ca(2+) required for contraction. Proper regulation of RyR2 is critical, as highlighted by the association between channel dysfunction an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5204e8e974e0acd7c513f6a927b7aa8d
https://doi.org/10.1016/j.yjmcc.2022.04.004
https://doi.org/10.1016/j.yjmcc.2022.04.004
Autor:
Willem J. De Lange, Emily T. Farrell, Jonathan J. Hernandez, Alana Stempien, Caroline R. Kreitzer, Derek R. Jacobs, Dominique L. Petty, Richard L. Moss, Wendy C. Crone, J. Carter Ralphe
Publikováno v:
Journal of General Physiology. 155
Truncation mutations in cardiac myosin binding protein C (cMyBP-C) are common causes of hypertrophic cardiomyopathy (HCM). Heterozygous carriers present with classical HCM, while homozygous carriers present with early onset HCM that rapidly progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28f148b02a41d4bfbb7519538279deb4
https://doi.org/10.1085/jgp.202213204
https://doi.org/10.1085/jgp.202213204
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one dono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb0fd611e546a81c790364831fec208
https://doaj.org/article/3492954afc4c45588e408ac2af1ac1b4
https://doaj.org/article/3492954afc4c45588e408ac2af1ac1b4
BackgroundMesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a4c168b31fa0f618083a2f41b1c136
https://doi.org/10.21203/rs.3.rs-154351/v1
https://doi.org/10.21203/rs.3.rs-154351/v1
Autor:
Ana P Lopes Chaves, Doyle E Beaty, J M Sloan, Neil H. Riordan, Jonathan J Hernandez, Logan L Fruhwirth
Mesenchymal stem cells derived from human umbilical cord (hUC-MSCs) have immunomodulatory properties that are of interest to treat novel coronavirus disease 2019 (COVID-19). Leng et al. recently reported that hUC-MSCs derived from one donor negativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2a8b15bc7af1b4772a32068c44c2906
https://doi.org/10.21203/rs.3.rs-36376/v1
https://doi.org/10.21203/rs.3.rs-36376/v1
Autor:
Eric G. Schmuck, Carter J. Ralphe, Jonathan J Hernandez, Yuriy V. Egorov, Zachary D. Piro, Evi Lim, Timothy J. Kamp, Amish N. Raval, Di Lang, Alexey V. Glukhov, Leonid V. Rosenshtraukh, Leonid Tyan, Daniel Turner, Rose Wang, Rylie Lodin
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Atrial fibrillation often occurs in the setting of hypertension and associated atrial dilation with pathologically increased cardiomyocyte stretch. In the setting of atrial dilation, mechanoelectric feedback has been linked to the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02161acbaa0d386fb828604c6d863e9
https://doi.org/10.1161/jaha.119.012748
https://doi.org/10.1161/jaha.119.012748
Autor:
Zhiguang Yuchi, Yan Chen, Jonathan J Hernandez, Michael J. Ackerman, Filip Van Petegem, Francisco J. Alvarado, J. Martijn Bos, Héctor H. Valdivia, Talia R. Booher, Carmen R. Valdivia, Dawn S. Henderlong, Cherisse A. Marcou, Yan-Ting Zhao
Publikováno v:
JCI Insight. 4
Hypertrophic cardiomyopathy (HCM) is triggered mainly by mutations in genes encoding sarcomeric proteins, but a significant proportion of patients lack a genetic diagnosis. We identified a potentially novel mutation in ryanodine receptor 2, RyR2-P112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c1ee6de625d53c7aa2225f6431f46f
https://doi.org/10.1172/jci.insight.126544
https://doi.org/10.1172/jci.insight.126544
Autor:
Yan-Ting Zhao, Héctor H. Valdivia, Carmen R. Valdivia, Georgina B. Gurrola, Jonathan J Hernandez
Publikováno v:
Science China. Life sciences
Ryanodine receptors (RyRs) are the calcium release channels of sarcoplasmic reticulum (SR) that provide the majority of calcium ions (Ca(2+)) necessary to induce contraction of cardiac and skeletal muscle cells. In their intracellular environment, Ry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716cb099932f8586cff2fcb923a7bd42
http://europepmc.org/articles/PMC6309702
http://europepmc.org/articles/PMC6309702