Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jonathan J. Geruntho"'
Autor:
Beatrice Langton-Webster, Charles M. Laymon, Brenda F. Kurland, Nathan Salamacha, Lora H. Rigatti, Hillarie P Windish, Jonathan J. Geruntho, Carolyn J. Anderson, Cindy J. Choy, Clifford E. Berkman, Ding Shen, Yijen L. Wu, Xiaoxi Ling, Joseph D. Latoche
Publikováno v:
Mol Imaging Biol
PURPOSE: Prostate-specific membrane antigen (PSMA) continues to be the hallmark biomarker for prostate cancer as it is expressed on nearly all prostatic tumors. In addition, increased PSMA expression correlates with castration resistance and progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f788677b41dc085d9aab3ce9bce79ae
https://doi.org/10.1007/s11307-019-01404-8
https://doi.org/10.1007/s11307-019-01404-8
Autor:
Clifford E. Berkman, M. Grant Norton, Oscar Marin-Flores, Parissa Ziaei, Jonathan J. Geruntho
Publikováno v:
Journal of Materials Science. 52:6907-6916
Early diagnosis of prostate cancer and evaluation of appropriate treatment options requires development of effective and high-throughput selective capture technology for exosomes that are positive for the expression of enzyme-biomarker, prostate-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::713875fbff102e7c03ce2c451692ddb1
https://doi.org/10.1007/s10853-017-0905-0
https://doi.org/10.1007/s10853-017-0905-0
Autor:
Xiaoxi Ling, Clifford E. Berkman, Joseph D. Latoche, Jonathan J. Geruntho, Sophia K. Beyer, Beatrice Langton-Webster, Carolyn J. Anderson, Cindy J. Choy
Publikováno v:
Theranostics. 7:1928-1939
Prostate-specific membrane antigen (PSMA) continues to be an active biomarker for small-molecule PSMA-targeted imaging and therapeutic agents for prostate cancer and various non-prostatic tumors that are characterized by PSMA expression on their neov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1737c0fa0eba17e645bd93d8d8efad52
https://doi.org/10.7150/thno.18719
https://doi.org/10.7150/thno.18719
Autor:
Henry F. VanBrocklin, Ella F. Jones, Christopher R. Drake, Hendry Cahaya, Sophia K. Beyer, Jonathan J. Geruntho, Shorouk Dannoon, Melanie Regan, Mark R. Hopkins, Lubica Skultetyova, Tanushree Ganguly, Salma Jivan, Cyril Barinka, Clifford E. Berkman, Cindy J. Choy, Matthew S. Galliher, Joseph E. Blecha
Publikováno v:
Journal of medicinal chemistry, vol 59, iss 12
A series of phosphoramidate-based prostate specific membrane antigen (PSMA) inhibitors of increasing lipophilicity were synthesized (4, 5, and 6), and their fluorine-18 analogs were evaluated for use as positron emission tomography (PET) imaging agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bf59a9232106e42328cef6839361ce
https://doi.org/10.1021/acs.jmedchem.5b01850
https://doi.org/10.1021/acs.jmedchem.5b01850
Publikováno v:
Bioconjugate Chemistry. 27:824-830
We have developed a novel pH-sensitive linker based on a phosphoramidate scaffold that can be tuned to release amine-containing drug molecules at various pH values. The pH-triggered phosphoramidate-based linkers are responsive to pH alone and do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432c6493ebd98c15c11b6e8ab2d99da2
https://doi.org/10.1021/acs.bioconjchem.6b00027
https://doi.org/10.1021/acs.bioconjchem.6b00027
Autor:
Clifford E. Berkman, Brian H. Clowers, Brian Scott Backer, Corinne Rose Ley, Cindy J. Choy, Jonathan J. Geruntho, Austen L. Davis
Publikováno v:
Bioconjugate chemistry. 27(9)
We developed a second generation of tunable pH-sensitive linkers based on our phosphoramidate scaffold to release amine-containing drugs under acidic conditions. The pH-triggered phosphoramidate-based linkers are responsive to pH and do not require i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a7e2c9e4ccb84948e3fe710f3a8a11
https://pubmed.ncbi.nlm.nih.gov/27562353
https://pubmed.ncbi.nlm.nih.gov/27562353
Autor:
Robert A. Richards, Matthew A. Zuchero, Brittney L. Tiley, Stefan Stoll, Evan A. Welker, Wing-Sze Tong, Jeffrey P. Wolbach, Ian J. Rhile, Crina M. Sasaran, Melissa J. Vettleson, Jonathan J. Geruntho
Publikováno v:
The Journal of organic chemistry. 80(17)
Proton-coupled electron transfer (PCET) model systems combine one-electron oxidants and bases to generate net hydrogen atom acceptors. We have generated two persistent pyridyl-appended radical cations: 10-(pyrid-2-yl)-10H-phenothiazinium (PPT•+) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa553d0e032e03122a752bd8527080a
https://pubmed.ncbi.nlm.nih.gov/26270193
https://pubmed.ncbi.nlm.nih.gov/26270193
Autor:
Lisa Y, Wu, Jacqueline M, Johnson, Jessica K, Simmons, Desiree E, Mendes, Jonathan J, Geruntho, Tiancheng, Liu, Wessel P, Dirksen, Thomas J, Rosol, William C, Davis, Clifford E, Berkman
Publikováno v:
The Prostate. 74(5)
Prostate-specific membrane antigen (PSMA) remains an important target for diagnostic and therapeutic application for human prostate cancer. Model cell lines have been recently developed to study canine prostate cancer but their PSMA expression and en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1695ccf5b475be6642c6c55e0deb289
https://pubmed.ncbi.nlm.nih.gov/24449207
https://pubmed.ncbi.nlm.nih.gov/24449207