Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jonathan J Hollick"'
Autor:
Rachel Ord, Ian Hickson, Mark Frigerio, Niall M. B. Martin, Sophie Guiard, Keith Allan Menear, Marc Geoffrey Hummersone, Celine Cano-Soumillac, Jonathan J Hollick, Xiao-Ling Fan Cockcroft, Roger J. Griffin, Laurent Rigoreau, Graeme C. M. Smith, Bernard T. Golding, Ian R. Hardcastle, Caroline Richardson, David R. Newell, Ian Timothy Williams Matthews, Nicola J. Curtin
Publikováno v:
Journal of medicinal chemistry. 50(8)
Structure-activity relationships have been investigated for inhibition of DNA-dependent protein kinase (DNA-PK) and ATM kinase by a series of pyran-2-ones, pyran-4-ones, thiopyran-4-ones, and pyridin-4-ones. A wide range of IC50 values were observed
Autor:
Jonathan J. Hollick, Laurent J. M. Rigoreau, Celine Cano-Soumillac, Xiaoling Cockcroft, Nicola J. Curtin, Mark Frigerio, Bernard T. Golding, Sophie Guiard, Ian R. Hardcastle, Ian Hickson, Marc G. Hummersone, Keith A. Menear, Niall M. B. Martin, Ian Matthews, David R. Newell, Rachel Ord, Caroline J. Richardson, Graeme C. M. Smith, Roger J. Griffin
Publikováno v:
Journal of Medicinal Chemistry; Apr2007, Vol. 50 Issue 8, p1958-1972, 15p