Zobrazeno 1 - 10
of 17 276
pro vyhledávání: '"Jonathan I"'
Autor:
Jonathan I. Silverberg, David Rosmarin, Raj Chovatiya, Thomas Bieber, Stephen Schleicher, Lisa Beck, Melinda Gooderham, Sohail Chaudhry, Christie Fanton, Danni Yu, Joshua Levy, Yi Liu, Takahiro Miyazaki, Mary Tagliaferri, Carsten Schmitz, Ajay Nirula, Brian Kotzin, Jonathan Zalevsky
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Regulatory T cell (Treg) impairment is implicated in the pathogenesis of chronic inflammatory diseases, but relatively little is known about the therapeutic potential of Treg restoration. Here we present clinical evidence for the Treg-select
Externí odkaz:
https://doaj.org/article/9bc93354dab940bc992d2c583c1fb98c
Autor:
Odeta Gelezelyte, Greta Guogaite, Auguste Nomeikaite, Jonathan I. Bisson, Catrin Lewis, Evaldas Kazlauskas
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Posttraumatic stress disorder (PTSD) is a common mental disorder. However, many cases of PTSD remain untreated because of limited healthcare resources and other treatment-seeking barriers. Effective internet-based interventions co
Externí odkaz:
https://doaj.org/article/f02420da9ecd480290f5ed960646d57e
Autor:
Yibing Zeng, Julian Somers, Harrison S. Bell, Zuzana Vejlupkova, R. Kelly Dawe, John E. Fowler, Brad Nelms, Jonathan I. Gent
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Although DNA methylation primarily represses TEs, it also represses select genes that are methylated in plant body tissues but demethylated by DNA glycosylases (DNGs) in endosperm or pollen. Either one of two DNGs, MATERNAL DEREPRESSION OF R
Externí odkaz:
https://doaj.org/article/b4c84bd9366d4b0dadc1d73666513c5c
Autor:
Eric Simpson, Peter Lio, Evangeline Pierce, Angel Cronin, Robert R. McLean, Thomas Eckmann, Amber Reck Atwater, Zach Dawson, Jonathan I. Silverberg
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 4, Pp 1061-1075 (2024)
Abstract Background Atopic dermatitis (AD) is associated with patient burden, but few studies describe the anatomic distribution of the disease or the impact of number of lesion locations. Objectives To describe lesion locations and assess the relati
Externí odkaz:
https://doaj.org/article/1df801ec59644b639d7259309537b19e
Autor:
Jonathan I. Silverberg, Feifei Yang, Evo Alemao, Jing Zhao, Concetta Crivera, Hetal V. Patel, Iris Lin, Aaron R. Mangold
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 4, Pp 1206-1211 (2024)
Abstract Background The potential association of long‐term oral corticosteroid (OCS) use with adverse events (AEs) in patients with bullous pemphigoid (BP) is not well characterized in a real‐world setting. Objectives To evaluate the effect of OC
Externí odkaz:
https://doaj.org/article/16ee0fb30da34575b66759ff2cd9c7a3
Publikováno v:
Bioactive Materials, Vol 43, Iss , Pp 114-128 (2025)
Decellularized tissues offer significant potential as biological materials for tissue regeneration given their ability to preserve the complex compositions and architecture of the native extracellular matrix (ECM). However, the evaluation and derivat
Externí odkaz:
https://doaj.org/article/83f19e7eafaf4d1e8a3eb85ae4a87f8e
Autor:
Ross O’Hagan, MD, Samir Kamat, MD, Shira Wieder, MD, Marcel Perl, MD, Jonathan I. Silverberg, MD, PhD, MPH, Nanette B. Silverberg, MD
Publikováno v:
JAAD International, Vol 16, Iss , Pp 127-129 (2024)
Externí odkaz:
https://doaj.org/article/50f00e523a2a42728cbc2035a0173e99
More Time Spent with Clear Skin and No Itch with Upadacitinib versus Dupilumab for Atopic Dermatitis
Autor:
Andrew Blauvelt, Kilian Eyerich, Alan D. Irvine, Marjolein de Bruin-Weller, Shawn G. Kwatra, Melinda Gooderham, Brian Kim, Brian M. Calimlim, Wan-Ju Lee, Eliza M. Raymundo, Yingyi Liu, Sarah Ofori, Andrew M. Platt, Jonathan I. Silverberg
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 9, Pp 2621-2630 (2024)
Abstract Introduction Atopic dermatitis (AD), with its hallmark symptoms of pruritus and skin lesions, often impairs patients’ quality of life. We assessed time spent with clear/almost clear skin and no/minimal itch during upadacitinib treatment ve
Externí odkaz:
https://doaj.org/article/f20cd55b09a34e87a0a91cfbd7f735cf
Autor:
Jonathan I. Silverberg, Andreas Wollenberg, Linda Stein Gold, James Del Rosso, Gil Yosipovitch, Peter Lio, Jose-Manuel Carrascosa, Gaia Gallo, Yuxin Ding, Zhenhui Xu, Marta Casillas, Evangeline Pierce, Helena Agell, Sonja Ständer
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 8, Pp 2249-2260 (2024)
Abstract Introduction Lebrikizumab is a novel monoclonal antibody with established efficacy in patients with moderate-to-severe atopic dermatitis (AD) in multiple Phase 3 trials. One of the ultimate treatment goals for patients with moderate-to-sever
Externí odkaz:
https://doaj.org/article/c3b82cefa2e141b9919ea988c75ddb9e
Autor:
April W. Armstrong, H. Chih-Ho Hong, Brian M. Calimlim, Marric G. Buessing, Marjorie M. Crowell, Jonathan I. Silverberg
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 9, Pp 2457-2465 (2024)
Abstract Introduction Efficacy of upadacitinib has been assessed in trials including Measure Up 1 (NCT03569293), Measure Up 2 (NCT03607422), and Heads Up (NCT03738397). Measure Up 1 and 2 assessed efficacy of upadacitinib 30 mg and upadacitinib 15 mg
Externí odkaz:
https://doaj.org/article/c50f79e2bc6f4b5e8459d5588f42735c