Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jonathan Hullmann"'
Autor:
Jessica I Gold, Jeffrey S Martini, Jonathan Hullmann, Erhe Gao, J Kurt Chuprun, Linda Lee, Douglas G Tilley, Joseph E Rabinowitz, Julie Bossuyt, Donald M Bers, Walter J Koch
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57324 (2013)
G protein-Coupled Receptors (GPCRs) kinases (GRKs) play a crucial role in regulating cardiac hypertrophy. Recent data from our lab has shown that, following ventricular pressure overload, GRK5, a primary cardiac GRK, facilitates maladaptive myocyte g
Externí odkaz:
https://doaj.org/article/f933052fcc7e42b0bf320c5f5af94e73
Publikováno v:
Pharmacological Research. 110:52-64
Heart failure (HF) is a global epidemic with the highest degree of mortality and morbidity of any disease presently studied. G protein-coupled receptors (GPCRs) are prominent regulators of cardiovascular function. Activated GPCRs are “turned off”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9740afbe33659d65420ed09241aee2f
https://doi.org/10.1016/j.phrs.2016.05.008
https://doi.org/10.1016/j.phrs.2016.05.008
Publikováno v:
Journal of Molecular and Cellular Cardiology. 92:196-202
As the average world-wide lifespan continues to increase, heart failure (HF) has dramatically increased in incidence leading to the highest degree of mortality and morbidity of any disease presently studied. G protein-coupled receptors (GPCRs) play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5625c4b564e3c1d33b3f16b14b8f0a
https://doi.org/10.1016/j.yjmcc.2016.01.027
https://doi.org/10.1016/j.yjmcc.2016.01.027
Autor:
Jessica Ibetti, Walter J. Koch, Yan Zhou, Jessica I. Gold, Benjamin P. Woodall, Christopher J. Traynham, Alessandro Cannavo, Alexandre G. Vouga, Erhe Gao, Jonathan Hullmann, J. Kurt Chuprun
Publikováno v:
Circulation Research. 117:1001-1012
Rationale : G protein–coupled receptor kinases (GRKs) are dynamic regulators of cellular signaling. GRK5 is highly expressed within myocardium and is upregulated in heart failure. Although GRK5 is a critical regulator of cardiac G protein–coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71c2aaba7af5c6cc3f9c58ac5b40293
https://doi.org/10.1161/circresaha.115.306961
https://doi.org/10.1161/circresaha.115.306961
Autor:
Jonathan Hullmann, Paul J. Mather
Publikováno v:
Progress in transplantation (Aliso Viejo, Calif.). 28(2)
Background: Despite ventricular assist devices (VADs) becoming more common in heart failure (HF) treatment, it is still uncertain which patients are more prone to complications. One potential risk factor is increased body mass index (BMI), which is k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4dc861ec2e9a07de729d1c03e5a12f3
https://pubmed.ncbi.nlm.nih.gov/29558875
https://pubmed.ncbi.nlm.nih.gov/29558875
Publikováno v:
Journal of Solid State Chemistry. 181:1909-1914
Three new compounds—Sr 7.04(2) Ga 1.94(2) Sb 6 , Ba 7.02(3) Ga 1.98(3) Sb 6 and Eu 7.04(3) Ga 1.90(3) Sb 6 —have been synthesized from reactions of the corresponding elements using gallium as a metal flux. Their crystal structures (space group I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9e0a0b66f1848bc8be5793c2166d84e
https://doi.org/10.1016/j.jssc.2008.04.004
https://doi.org/10.1016/j.jssc.2008.04.004
Autor:
Erhe Gao, Douglass G. Tilley, Jessica I. Gold, Steven R. Houser, Jonathan Hullmann, Walter J. Koch, J. Kurt Chuprun, Catherine A. Makarewich, Laurel A. Grisanti
Publikováno v:
Circulation research. 115(12)
Rationale : G protein–coupled receptor kinases (GRKs) acting in the cardiomyocyte regulate important signaling events that control cardiac function. Both GRK2 and GRK5, the predominant GRKs expressed in the heart, have been shown to be upregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc729b223ca03d5ee222318214c40f13
https://pubmed.ncbi.nlm.nih.gov/25332207
https://pubmed.ncbi.nlm.nih.gov/25332207
Autor:
Jonathan Hullmann, Jessica L Gold, Christopher J. Traynham, Alessandro Cannavo, Walter J. Koch
Publikováno v:
Circulation Research. 115
Cardiac function is dynamically regulated by various G protein-coupled receptors (GPCRs). GPCR kinases (GRKs) are important in cardiac GPCR regulation through phosphorylation and desensitization of these receptors. GRK2 and GRK5 are the predominant G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06a4cbc41ef8d283d2e02417f6dea777
https://doi.org/10.1161/res.115.suppl_1.169
https://doi.org/10.1161/res.115.suppl_1.169
Publikováno v:
Circulation Research. 113
Introduction: G protein-coupled receptor (GPCR) kinase-2 and -5 (GRK2 and GRK5) have been shown to be up-regulated in failing human myocardium. While the canonical role of GRKs is to desensitize receptors via phosphorylation, it has been shown that G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb8c8091ca1678230f2726197a038ba
https://doi.org/10.1161/res.113.suppl_1.a074
https://doi.org/10.1161/res.113.suppl_1.a074
Autor:
Jonathan Hullmann, Douglas G. Tilley, Joseph E. Rabinowitz, Jeffrey S. Martini, Erhe Gao, Linda L. Lee, Walter J. Koch, J. Kurt Chuprun, Jessica I. Gold, Donald M. Bers, Julie Bossuyt
Publikováno v:
PLoS ONE
PloS one, vol 8, iss 3
PLoS ONE, Vol 8, Iss 3, p e57324 (2013)
PloS one, vol 8, iss 3
PLoS ONE, Vol 8, Iss 3, p e57324 (2013)
G protein-Coupled Receptors (GPCRs) kinases (GRKs) play a crucial role in regulating cardiac hypertrophy. Recent data from our lab has shown that, following ventricular pressure overload, GRK5, a primary cardiac GRK, facilitates maladaptive myocyte g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041658f11ca255c00c9e2480a0820e95
http://europepmc.org/articles/PMC3589474
http://europepmc.org/articles/PMC3589474