Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jonathan Higham"'
Autor:
Jonathan Higham, Lyndsay Kerr, Qian Zhang, Rosie M. Walker, Sarah E. Harris, David M. Howard, Emma L. Hawkins, Anca-Larisa Sandu, J. Douglas Steele, Gordon D. Waiter, Alison D. Murray, Kathryn L. Evans, Andrew M. McIntosh, Peter M. Visscher, Ian J. Deary, Simon R. Cox, Duncan Sproul
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-28 (2022)
Abstract Background DNA methylation is an epigenetic mark associated with the repression of gene promoters. Its pattern in the genome is disrupted with age and these changes can be used to statistically predict age with epigenetic clocks. Altered rat
Externí odkaz:
https://doaj.org/article/4a8ed727d825483db65eb461688f51e5
Autor:
Roza H. Ali Masalmeh, Francesca Taglini, Cristina Rubio-Ramon, Kamila I. Musialik, Jonathan Higham, Hazel Davidson-Smith, Ioannis Kafetzopoulos, Kamila P. Pawlicka, Hannah M. Finan, Richard Clark, Jimi Wills, Andrew J. Finch, Lee Murphy, Duncan Sproul
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Aberrant gain of DNA methylation at CpG islands is frequently observed in colorectal tumours. Here the authors use ectopically integrated CpG islands in colorectal cancer cells and find that aberrantly methylated CpG islands are subject to low levels
Externí odkaz:
https://doaj.org/article/9803ec9958634a5e94312be4787e0b29
Autor:
Hemalvi Patani, Michael D. Rushton, Jonathan Higham, Saul A. Teijeiro, David Oxley, Pedro Cutillas, Duncan Sproul, Gabriella Ficz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Epigenetic reprogramming is a hallmark of cancer. Here the authors find that resetting primed human embryonic stem cells to naïve state results in the acquisition of a DNA methylation landscape that mirrors the cancer DNA methylome and provides evid
Externí odkaz:
https://doaj.org/article/9c90c9bfb585432585f2d24ff10bd5ed
Publikováno v:
Geosciences, Vol 11, Iss 12, p 494 (2021)
Spatially explicit data on tidal and waves are required as part of coastal monitoring applications (e.g., radar monitoring of coastal change) for the design of interventions to mitigate the impacts of climate change. A deployment over two tidal cycle
Externí odkaz:
https://doaj.org/article/e5632c4cc66a48f2b3d4b9ccb60aefd1
Publikováno v:
Entropy, Vol 21, Iss 8, p 750 (2019)
Accurately calculating the entropy of liquids is an important goal, given that many processes take place in the liquid phase. Of almost equal importance is understanding the values obtained. However, there are few methods that can calculate the entro
Externí odkaz:
https://doaj.org/article/df14ba20f46b41daab467b783f9e3eb8
Autor:
Erick A Perez Alday, Michael A Colman, Philip Langley, Timothy D Butters, Jonathan Higham, Antony J Workman, Jules C Hancox, Henggui Zhang
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 1, p e1004026 (2015)
Rapid atrial arrhythmias such as atrial fibrillation (AF) predispose to ventricular arrhythmias, sudden cardiac death and stroke. Identifying the origin of atrial ectopic activity from the electrocardiogram (ECG) can help to diagnose the early onset
Externí odkaz:
https://doaj.org/article/4eac07f94f964133a16c8d1881f28eb0
Publikováno v:
Journal of Visualization. 26:563-576
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae87d4e9c6580c8529479df76829f985
https://doi.org/10.1007/s12650-022-00902-2
https://doi.org/10.1007/s12650-022-00902-2
Autor:
Jonathan Higham, Cammy Acosta Ramirez
Publikováno v:
METEOROLOGICAL APPLICATIONS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fed3c6f090e03317d379216e258109
https://doi.org/10.1002/met.2061
https://doi.org/10.1002/met.2061
Publikováno v:
Air Quality, Atmosphere, & Health
Air Quality, Atmosphere & Health
Air Quality, Atmosphere & Health
On the 23 March 2020, a country-wide COVID-19 lockdown was imposed on the UK. The following 100 days saw anthropogenic movements quickly halt, before slowly easing back to a “new” normality. In this short communication, we use data from official
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69a4c65624bb73e319bc702b1d8a9ac
https://doi.org/10.1007/s11869-020-00937-0
https://doi.org/10.1007/s11869-020-00937-0
Autor:
Jonathan Higham, Allan Issangya, Casey Q. LaMarche, Christine M. Hrenya, Ray Cocco, William D. Fullmer
Publikováno v:
Powder Technology
Image-based velocimetry methods have become a widely used method to characterize solids velocity fields in particulate devices; two of the most commonly used methods being particle image velocimetry (PIV) and particle tracking velocimetry (PIV). Ofte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dd4922fd10b03609228852f39e4ac9
https://doi.org/10.1016/j.powtec.2019.09.073
https://doi.org/10.1016/j.powtec.2019.09.073