Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jonathan H. Sussman"'
Autor:
Dominic J. Romeo, Andrew M. George, Jonathan H. Sussman, Manisha Banala, Andrew Wiemken, Meagan Wu, Jinggang J. Ng, Jesse A. Taylor, Richard J. Schwab, Christopher M. Cielo, Jennifer M. Kalish
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background An easy-to-use tool to objectively measure intraoral anatomy with meaningful clinical correlations may improve care for patients with Beckwith-Wiedemann syndrome (BWS), who commonly have symptomatic macroglossia. Methods Children
Externí odkaz:
https://doaj.org/article/c7609992021c4610bd3344d4bb275448
Autor:
Takeshi Katsuda, Jonathan H. Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J. Merrell, Hector Cure, Qinglan Li, Reyaz Ur Rasool, Irfan A. Asangani, Kenneth S. Zaret, Ben Z. Stanger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is activated has not been investigated in animals. In cell culture, pioneer transcription factors
Externí odkaz:
https://doaj.org/article/b2c5a3c430084dd3bae1dbe3580360ff
Autor:
Emily Xu, Jonathan Patterson, Angelo Angione, Alexander Li, David W. Wu, Ebrar Akca, Omar Elghawy, Alexander Barsouk, Jonathan H. Sussman
Publikováno v:
Life, Vol 14, Iss 9, p 1133 (2024)
Low-grade glioma (LGG) is a malignancy of the central nervous system that is often treatable with surgical resection and chemoradiation. However, despite an initial positive response to standard therapy, most LGG eventually progress to high-grade gli
Externí odkaz:
https://doaj.org/article/4efa81cc7bdf46fb88b1e8d7559f19af
Autor:
Angelo Angione, Jonathan Patterson, Ebrar Akca, Jessica Xu, Emily Xu, Vanessa Raab, Omar Elghawy, Adam A. Barsouk, Jonathan H. Sussman
Publikováno v:
Life, Vol 14, Iss 8, p 926 (2024)
High-grade glioma is the most frequent and lethal primary tumor of the central nervous system. Despite advances in surgical, pharmacological, and cell-directed therapies, there have been no updates to the standard of care in over a decade. This cross
Externí odkaz:
https://doaj.org/article/fa57c98748344a23925eecca0cb6fb16
Autor:
Rachit Kumar, Jordan Setayesh, Amitej Venapally, Chelsea Nnebe, Jonathan H. Sussman, Natalie Guzman, Carl Bannerman
Publikováno v:
Molecular Biology of the Cell
The importance of diversity is self-evident in medicine and medical research. Not only does diversity result in more impactful scientific work, but diverse teams of researchers and clinicians are necessary to address health disparities and improve th
Autor:
Jonathan H. Sussman, Matthew P. Jeon, Melanie A. MacMullan, Sydney Parrish, Nicholas A. Graham, Dongqing Zheng, Alireza Delfarah
Publikováno v:
Journal of cell science. 133(7)
Oncogenes can create metabolic vulnerabilities in cancer cells. We tested how AKT (herein referring to AKT1) and MYC affect the ability of cells to shift between respiration and glycolysis. Using immortalized mammary epithelial cells, we discovered t