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pro vyhledávání: '"Jonathan H. Lindsay"'
Autor:
Laura D. Mathies, Jonathan H. Lindsay, Amal P. Handal, GinaMari G. Blackwell, Andrew G. Davies, Jill C. Bettinger
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background SWI/SNF chromatin remodeling genes are required for normal acute responses to alcohol in C. elegans and are associated with alcohol use disorder in two human populations. In an effort to discover the downstream genes that are medi
Externí odkaz:
https://doaj.org/article/025ec211bcd543d4a0213fc7c65606e8
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Alcohol intoxication can impact learning and this may contribute to the development of problematic alcohol use. In alcohol (ethanol)-induced state-dependent learning (SDL), information learned while an animal is intoxicated is recalled more effective
Autor:
Amal P. Handal, Laura D. Mathies, GinaMari G. Blackwell, Jonathan H. Lindsay, Andrew G. Davies, Jill C. Bettinger
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
BMC Genomics
BMC Genomics
Background SWI/SNF chromatin remodeling genes are required for normal acute responses to alcohol in C. elegans and are associated with alcohol use disorder in two human populations. In an effort to discover the downstream genes that are mediating thi
Publikováno v:
Alcoholism, clinical and experimental research. 42(2)
BACKGROUND Alcohol tolerance and withdrawal-induced effects are criteria for alcohol use disorders listed by the DSM-V. Although tolerance and withdrawal have been studied over many decades, there is still uncertainty regarding mechanistic distinctio
Publikováno v:
Alcoholism: Clinical and Experimental Research. 38:760-769
Ethanol (EtOH) triggers cellular adaptations that induce tolerance in many brain areas, including the suprachiasmatic nucleus (SCN), the site of the master circadian clock. EtOH inhibits light-induced phase shifts in the SCN in vivo and glutamate-ind
Publikováno v:
Proceedings of the 2014 Biomedical Sciences and Engineering Conference.
Alcohol abuse leads to cognitive defects, depression, and sleep disturbances. The connection between sleep and circadian disruptions led us to investigate ethanol's effect on the circadian clock. We demonstrated that acute ethanol blocks photic phase