Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jonathan H. Dennis"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
CRISPR-Cas based virus detection assays can be both rapid and sensitive. Here the authors use a Type III-A CRISPR-Cas system to detect SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/161706c84d344a00814531cbfef33077
Autor:
Lauren Cole, Sebastian Kurscheid, Maxim Nekrasov, Renae Domaschenz, Daniel L. Vera, Jonathan H. Dennis, David J. Tremethick
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Histone variant H2A.Z has been suggested to contribute to the regulation of promoter accessibility. Here, the authors present high-depth maps of the position and accessibility of H2A.Z-containing nucleosomes for human Pol II promoters and provide evi
Externí odkaz:
https://doaj.org/article/3dd420dcdf0c40f78d943734cd5023b8
Autor:
Zachary M. Turpin, Daniel L. Vera, Savannah D. Savadel, Pei-Yau Lung, Emily E. Wear, Leigh Mickelson-Young, William F. Thompson, Linda Hanley-Bowdoin, Jonathan H. Dennis, Jinfeng Zhang, Hank W. Bass
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 358-363 (2018)
Presented here are data from Next-Generation Sequencing of differential micrococcal nuclease digestions of formaldehyde-crosslinked chromatin in selected tissues of maize (Zea mays) inbred line B73. Supplemental materials include a wet-bench protocol
Externí odkaz:
https://doaj.org/article/c1c0cbd8d1ac4beeab9551e58d79fd16
Autor:
Senthil B. Girimurugan, Yuhang Liu, Pei-Yau Lung, Daniel L. Vera, Jonathan H. Dennis, Hank W. Bass, Jinfeng Zhang
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-15 (2018)
Abstract Background Identification of functional elements of a genome often requires dividing a sequence of measurements along a genome into segments where adjacent segments have different properties, such as different mean values. Despite dozens of
Externí odkaz:
https://doaj.org/article/89bcb4d264364b5f8f7e3fbca22d0182
Publikováno v:
Genomics Data, Vol 2, Iss C, Pp 114-116 (2014)
In the eukaryotic nucleus, DNA is packaged into chromatin. The fundamental subunit of chromatin is the nucleosome, DNA is wrapped 1.6 times around a histone octamer core. Nuclear processes in eukaryotes are impacted by whether regulatory DNA is occup
Externí odkaz:
https://doaj.org/article/a94811f8cf5e4df48acba94ce59e59d6
Publikováno v:
International Journal of Genomics, Vol 2015 (2015)
The regulation of metazoan gene expression occurs in part by pre-mRNA splicing into mature RNAs. Signals affecting the efficiency and specificity with which introns are removed have not been completely elucidated. Splicing likely occurs cotranscripti
Externí odkaz:
https://doaj.org/article/d8808cafe3d244f0ad5ab8c60b8b46c8
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 146-147 (2015)
In eukaryotes, nucleosomes participate in all DNA-templated events by regulating access to the underlying DNA sequence. However, nucleosome dynamics during a genome response have not been well characterized [1,2]. We stimulated Drosophila S2 cells wi
Externí odkaz:
https://doaj.org/article/136b24a920b540d0a91d290f18cdc9cd
Autor:
Mahdi Khadem, Kimberlee Kossick, Yaroslav Fedyshyn, Lisa Boardman, Jonathan H. Dennis, Brooke R. Druliner
One of the keys to eliminating the personal and financial costs of cancer lies in the early detection of the disease. Consequently, effective cancer interventions increasingly rely on our understanding of the earliest cellular and nuclear events that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac31162041f6300383a8473bb0836770
https://doi.org/10.1101/2022.11.08.515478
https://doi.org/10.1101/2022.11.08.515478
Autor:
David J. Tremethick, Renae Domaschenz, Maxim Nekrasov, Sebastian Kurscheid, Daniel L. Vera, Lauren Cole, Jonathan H. Dennis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Chromatin accessibility of a promoter is fundamental in regulating transcriptional activity. The histone variant H2A.Z has been shown to contribute to this regulation, but its role has remained poorly understood. Here, we prepare high-depth maps of t
Autor:
Jonathan H. Dennis, Lauren Cole
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2171-2178 (2020)
The nucleosome is the primary unit of chromatin structure and commonly imputed as a regulator of nuclear events, although the exact mechanisms remain unclear. Recent studies have shown that certain nucleosomes can have different sensitivities to micr