Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jonathan H. Cove"'
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: To investigate the antistaphylococcal/antibiofilm activity and mode of action (MOA) of a panel of redox-active (RA) compounds with a history of human use and to provide a preliminary preclinical assessment of their potential for topical t
Publikováno v:
Journal of Antimicrobial Chemotherapy
Objectives: Tert-butyl benzoquinone (TBBQ) is the oxidation product of tert-butyl hydroquinone (TBHQ), an antimicrobial food additive with >40 years of safe use. TBBQ displays potent activity against Staphylococcus aureus biofilms in vitro. Here, we
Autor:
Jonathan H. Cove, Elinor Reynolds
Publikováno v:
Journal of Antimicrobial Chemotherapy. 55:260-264
Objectives: The msrC gene, found on the chromosome of Enterococcus faecium, shares a high degree of similarity with the staphylococcal erythromycin resistance determinant msr(A). The enterococcal determinant was cloned into Staphylococcus aureus to d
Autor:
Anne E. Eady, Jonathan H. Cove
Publikováno v:
Current Opinion in Internal Medicine. 2:238-259
Autor:
E.A. Eady, P. Coates, M.S. Murtagh, Jonathan H. Cove, M. Walker, Alison M. Layton, Jane Ravenscroft
Publikováno v:
British Journal of Dermatology. 148:1010-1017
Summary Background Staphylococcus aureus has a role in the pathophysiology of atopic eczema. Topical fusidic acid is widely used in its treatment. There is concern that topical use of fusidic acid may be driving the selection and dissemination of fus
Publikováno v:
Clinical Microbiology and Infection. 4:450-459
Objective To investigate the ability of both clinical and environmental strains of Burkholderia cepacia , along with control strains of Pseudomonas aeruginosa and Escherichia coli , to invade a respiratory epithelial cell line, A549. Methods and Resu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:1702-1705
A genetic basis for tetracycline resistance in cutaneous propionibacteria was suggested by comparing the nucleotide sequences of the 16S rRNA genes from 16 susceptible and 21 resistant clinical isolates and 6 laboratory-selected tetracycline-resistan
Autor:
Jonathan H. Cove, E. Anne Eady
Publikováno v:
Clinics in Dermatology. 16:141-147
Publikováno v:
The Journal of antimicrobial chemotherapy. 68(6)
Objectives The antioxidant tert-butylhydroquinone (TBHQ) is a food additive reported to have antibacterial activity, and may therefore have application in the healthcare setting. This study sought to characterize the antibacterial activity and mode o
Publikováno v:
BioMed Research International, Vol 2013 (2013)
BioMed Research International
BioMed Research International
Today, as 40 years ago, we still rely on a limited number of antibiotics and benzoyl peroxide to treat inflammatory acne. An alternative way of suppressing the growth of Propionibacterium acnes is to target the environment in which it thrives. We con