Zobrazeno 1 - 10
of 486
pro vyhledávání: '"Jonathan Graff‐Radford"'
Autor:
Kevin A. Mazurek, Leland Barnard, Hugo Botha, Teresa Christianson, Jonathan Graff-Radford, Ronald Petersen, Prashanthi Vemuri, B. Gwen Windham, David T. Jones, Farwa Ali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Digital quantification of gait can be used to measure aging- and disease-related decline in mobility. Gait performance also predicts prognosis, disease progression, and response to therapies. Most gait analysis systems require large amounts
Externí odkaz:
https://doaj.org/article/465e6866d8d6451c8cc4ebc456834d5a
Autor:
Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricu
Externí odkaz:
https://doaj.org/article/e98a5ea8c19f4da7a4b877bae77a1e08
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Autor:
Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Jr, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci, Jennifer L. Whitwell
Publikováno v:
NeuroImage, Vol 290, Iss , Pp 120564- (2024)
Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) show distinct atrophy and overlapping hypometabolism profiles, but it is unknown how disruptions in structural and functional connectivity compare between these disorders and whethe
Externí odkaz:
https://doaj.org/article/c9523c15658b48e5b201ae474cbd48e7
Autor:
Neha Singh-Reilly, Hugo Botha, Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Mary M. Machulda, Jonathan Graff-Radford, Christopher G. Schwarz, Ronald C. Petersen, Val J. Lowe, Clifford R. Jack, Jr, Keith A. Josephs, Jennifer L. Whitwell
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103639- (2024)
Primary progressive aphasia (PPA) variants present with distinct disruptions in speech-language functions with little known about the interplay between affected and spared regions within the speech-language network and their interaction with other fu
Externí odkaz:
https://doaj.org/article/67ce0fdfcf9a4894abf06efac9019079
Autor:
Dror Shir, Jonathan Graff-Radford, Angela J. Fought, Timothy G. Lesnick, Scott A. Przybelski, Maria Vassilaki, Val J. Lowe, David S. Knopman, Mary M. Machulda, Ronald C. Petersen, Clifford R. Jack, Jr, Michelle M. Mielke, Prashanthi Vemuri
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103634- (2024)
Introduction: AD and CVD, which frequently co-occur, are leading causes of age-related cognitive decline. We assessed how demographic factors, socioeconomic status (SES) as indicated by education and occupation, vascular risk factors, and a range of
Externí odkaz:
https://doaj.org/article/feaeeef564a042beb90734dee33646ca
Autor:
Daniel J. Figdore, Heather J. Wiste, Joshua A. Bornhorst, Randall J. Bateman, Yan Li, Jonathan Graff‐Radford, David S. Knopman, Prashanthi Vemuri, Val J. Lowe, Clifford R. Jack Jr, Ronald C. Petersen, Alicia Algeciras‐Schimnich
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION This study evaluated the performance of the Lumipulse plasma beta‐amyloid (Aβ) 42/40 and pTau181 compared to other assays to detect an abnormal amyloid‐positron emission tomography (PET). METHODS Plasma samples from cogniti
Externí odkaz:
https://doaj.org/article/58bfb3ece9c642f09b11f2a1ba46b37d
Autor:
Nick Corriveau-Lecavalier, Leland R. Barnard, Scott A. Przybelski, Venkatsampath Gogineni, Hugo Botha, Jonathan Graff-Radford, Vijay K. Ramanan, Leah K. Forsberg, Julie A. Fields, Mary M. Machulda, Rosa Rademakers, Ralitza H. Gavrilova, Maria I. Lapid, Bradley F. Boeve, David S. Knopman, Val J. Lowe, Ronald C. Petersen, Clifford R. Jack, Kejal Kantarci, David T. Jones
Publikováno v:
NeuroImage: Clinical, Vol 41, Iss , Pp 103559- (2024)
Genetic mutations causative of frontotemporal lobar degeneration (FTLD) are highly predictive of a specific proteinopathy, but there exists substantial inter-individual variability in their patterns of network degeneration and clinical manifestations
Externí odkaz:
https://doaj.org/article/70c787dd63d643fea9b1dbdf0ec4a2cf
Autor:
Sahith Reddy Thotamgari, MD, Akhilesh Babbili, MD, Prabandh Bucchanolla, MD, Samarthkumar Thakkar, MD, Harsh P. Patel, MD, Maja B. Spaseski, MD, Jonathan Graff-Radford, MD, Alejandro A. Rabinstein, MD, Zain Ul Abideen Asad, MD, MS, Samuel J. Asirvatham, MD, David R. Holmes, Jr., MD, Abhishek Deshmukh, MD, Christopher V. DeSimone, MD, PhD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 7, Iss 4, Pp 222-230 (2023)
Objective: To assess the effect of atrial fibrillation (AF) on outcomes in hospitalizations for non-traumatic intracerebral hemorrhage (ICH). Patients and Methods: We queried the National Inpatient Sample database between January 1, 2016, and Decembe
Externí odkaz:
https://doaj.org/article/52271cbfd4ac4150a884c1b29819b71b