Zobrazeno 1 - 10
of 950
pro vyhledávání: '"Jonathan Graff‐Radford"'
Autor:
Kevin A. Mazurek, Leland Barnard, Hugo Botha, Teresa Christianson, Jonathan Graff-Radford, Ronald Petersen, Prashanthi Vemuri, B. Gwen Windham, David T. Jones, Farwa Ali
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Digital quantification of gait can be used to measure aging- and disease-related decline in mobility. Gait performance also predicts prognosis, disease progression, and response to therapies. Most gait analysis systems require large amounts
Externí odkaz:
https://doaj.org/article/465e6866d8d6451c8cc4ebc456834d5a
Autor:
Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricu
Externí odkaz:
https://doaj.org/article/e98a5ea8c19f4da7a4b877bae77a1e08
Autor:
Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer’s disease, we performed single nucleus RNA sequencing in 24 Alzheimer’s disease and control brains and focused on vascular and astrocyte clusters as mai
Externí odkaz:
https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b
Autor:
Kevin A. Mazurek, Ph.D., Leland Barnard, Ph.D., Hugo Botha, M.B., Ch.B., Teresa Christianson, Jonathan Graff-Radford, M.D., David T. Jones, M.D., David S. Knopman, M.D., Ronald C. Petersen, M.D., Ph.D., Prashanthi Vemuri, Ph.D., Clifford R. Jack, Jr., M.D., Farwa Ali, M.B.B.S.
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 2, Iss 3, Pp 491- (2024)
Externí odkaz:
https://doaj.org/article/6c58504e92cc4442a4ec4b007fa37d15
Autor:
Elijah Mak, Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Sheelakumari Raghavan, Prashanthi Vemuri, Clifford R. Jack, Hoon Ki Min, Manoj K. Jain, Toji Miyagawa, Leah K. Forsberg, Julie A. Fields, Rodolfo Savica, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Erik K. St. Louis, David S. Knopman, Vijay K. Ramanan, Dennis W. Dickson, Neill R. Graff-Radford, Tanis J. Ferman, Ronald C. Petersen, Val J. Lowe, Bradley F. Boeve, John T. O’Brien, Kejal Kantarci
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with Alzheimer’s disease (AD) pathology. Characterizing white matter tissue microstructure using Neurite Orientation Dispersion and Density Imaging (NODDI)
Externí odkaz:
https://doaj.org/article/149702719cdf4981a0894fd359d25ace
Autor:
Pragalv Karki, Stephanie Sincomb, Matthew C. Murphy, Jeffrey L. Gunter, Matthew L. Senjem, Jonathan Graff-Radford, David T. Jones, Hugo Botha, Jeremy K. Cutsforth-Gregory, Benjamin D. Elder, John Huston, III, Petrice M. Cogswell
Publikováno v:
Brain Multiphysics, Vol 7, Iss , Pp 100101- (2024)
Background and purpose: Idiopathic normal pressure hydrocephalus (iNPH) is a cerebrospinal fluid (CSF) dynamics disorder as evidenced by the delayed ascent of radiotracers over the cerebral convexity on radionuclide cisternography. However, the exact
Externí odkaz:
https://doaj.org/article/21e0c4ca01464a188084e7be2da6d51c
Autor:
Xi Yu, Scott A. Przybelski, Robert I. Reid, Timothy G. Lesnick, Sheelakumari Raghavan, Jonathan Graff‐Radford, Val J. Lowe, Kejal Kantarci, David S. Knopman, Ronald C. Petersen, Clifford R. Jack Jr., Prashanthi Vemuri
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Age‐related and Alzheimer's disease (AD) dementia–related neurodegeneration impact brain health. While morphometric measures from T1‐weighted scans are established biomarkers, they may be less sensitive to earlier changes.
Externí odkaz:
https://doaj.org/article/68f17f5c04e049068a8e8c8632f60d2c
Autor:
Neha Atulkumar Singh, Austin W. Goodrich, Jonathan Graff-Radford, Mary M. Machulda, Irene Sintini, Arenn F. Carlos, Carling G. Robinson, Robert I. Reid, Val J. Lowe, Clifford R. Jack, Jr, Ronald C. Petersen, Bradley F. Boeve, Keith A. Josephs, Kejal Kantarci, Jennifer L. Whitwell
Publikováno v:
NeuroImage, Vol 290, Iss , Pp 120564- (2024)
Posterior cortical atrophy (PCA) and dementia with Lewy bodies (DLB) show distinct atrophy and overlapping hypometabolism profiles, but it is unknown how disruptions in structural and functional connectivity compare between these disorders and whethe
Externí odkaz:
https://doaj.org/article/c9523c15658b48e5b201ae474cbd48e7
Autor:
Sahith Reddy Thotamgari, MD, Akhilesh Babbili, MD, Prabandh Bucchanolla, MD, Samarthkumar Thakkar, MD, Harsh P. Patel, MD, Maja B. Spaseski, MD, Jonathan Graff-Radford, MD, Alejandro A. Rabinstein, MD, Zain Ul Abideen Asad, MD, MS, Samuel J. Asirvatham, MD, David R. Holmes, Jr., MD, Abhishek Deshmukh, MD, Christopher V. DeSimone, MD, PhD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 7, Iss 4, Pp 222-230 (2023)
Objective: To assess the effect of atrial fibrillation (AF) on outcomes in hospitalizations for non-traumatic intracerebral hemorrhage (ICH). Patients and Methods: We queried the National Inpatient Sample database between January 1, 2016, and Decembe
Externí odkaz:
https://doaj.org/article/52271cbfd4ac4150a884c1b29819b71b
Autor:
Petrice M. Cogswell, Emily S. Lundt, Terry M. Therneau, Carly T. Mester, Heather J. Wiste, Jonathan Graff-Radford, Christopher G. Schwarz, Matthew L. Senjem, Jeffrey L. Gunter, Robert I. Reid, Scott A. Przybelski, David S. Knopman, Prashanthi Vemuri, Ronald C. Petersen, Clifford R. Jack
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Whether a relationship exists between cerebrovascular disease and Alzheimer’s disease has been a source of controversy. Evaluation of the temporal progression of imaging biomarkers of these disease processes may inform mechanistic associat
Externí odkaz:
https://doaj.org/article/6b14808e32cc40c1b3bdafb954652a84