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pro vyhledávání: '"Jonathan Gane"'
Publikováno v:
Epilepsy & Behavior. 98:153-160
About one-third of people with epilepsy experience comorbid depression. The present study examined outcomes of a distance-delivery group intervention program designed to improve emotional well-being. Participants were 55 adults with epilepsy and self
Publikováno v:
Neuroscience. 257:65-75
Progesterone is a known anticonvulsant, with its inhibitory effects generally attributed to its secondary metabolite, 5α,3α-tetrahydroprogesterone (THP), and THP's enhancement of GABAA receptor activity. Accumulating evidence, however, suggests tha
Autor:
Tariq Zahid, Liang Zhang, Chiping Wu, Taufik A. Valiante, Homeira Moradi-Chameh, Min Lang, Jonathan Gane
Publikováno v:
Physiological Reports
Disturbances of GABAergic inhibition are a major cause of epileptic seizures. GABA exerts its actions via ionotropic GABAA receptors and metabotropic G protein‐coupled GABAB receptors. Malfunction of GABAA inhibition has long been recognized in sei
Publikováno v:
BMC Neuroscience
Background Electrical stimulation of brain structures has been widely used in rodent models for kindling or modeling deep brain stimulation used clinically. This requires surgical implantation of intracranial electrodes and subsequent chronic stimula