Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jonathan G. Zins"'
Autor:
Jeovanna Lowe, Peter Kolkhof, Michael J. Haupt, Kyra K. Peczkowski, Neha Rastogi, J. Spencer Hauck, Feni K. Kadakia, Jonathan G. Zins, Pierce C. Ciccone, Suzanne Smart, Peter Sandner, Subha V. Raman, Paul M.L. Janssen, Jill A. Rafael‐Fortney
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3983-3995 (2020)
Abstract Aims Duchenne muscular dystrophy (DMD) is an X‐linked inherited disease due to dystrophin deficiency causing skeletal and cardiac muscle dysfunction. Affected patients lose ambulation by age 12 and usually die in the second to third decade
Externí odkaz:
https://doaj.org/article/4cff7ed878c74318a756cc0a65441525
Autor:
Peter Sandner, Pierce C. Ciccone, Feni K. Kadakia, Jonathan G. Zins, Kyra K. Peczkowski, Suzanne Smart, Jill A. Rafael-Fortney, Neha Rastogi, Paul M.L. Janssen, Jeovanna Lowe, Peter Kolkhof, Michael J. Haupt, Subha V. Raman, J. Spencer Hauck
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3983-3995 (2020)
ESC Heart Failure
ESC Heart Failure
Aims Duchenne muscular dystrophy (DMD) is an X‐linked inherited disease due to dystrophin deficiency causing skeletal and cardiac muscle dysfunction. Affected patients lose ambulation by age 12 and usually die in the second to third decades of life
Autor:
Noah Weisleder, Jennifer M. Petrosino, Kevin E. McElhanon, Jill A. Rafael-Fortney, Jonathan G. Zins, Neha Rastogi, Paul M.L. Janssen, Kyra K. Peczkowski, Jeovanna Lowe, Federica Accornero, J. Spencer Hauck, Ashlee N Chadwick
Publikováno v:
Hum Mol Genet
Mineralocorticoid receptor (MR) drugs have been used clinically for decades to treat cardiovascular diseases. MR antagonists not only show preclinical efficacy for heart in Duchenne muscular dystrophy (DMD) models but also improve skeletal muscle for
Autor:
Feni K. Kadakia, Jill A. Rafael-Fortney, Neha Rastogi, Elise P. Gomez-Sanchez, Paul M.L. Janssen, Celso E. Gomez-Sanchez, Mohammad T. Elnakish, Kyle T. Floyd, Jonathan G. Zins, Jeovanna Lowe, Kyra K. Peczkowski, Michael J. Haupt
Publikováno v:
Journal of neuromuscular diseases. 5(3)
BACKGROUND: Mineralocorticoid receptor antagonists added to angiotensin converting enzyme inhibitors have shown pre-clinical efficacy for both skeletal and cardiac muscle outcomes in young sedentary dystrophin-deficient mdx mice also haploinsufficien
Autor:
Eric J. Schultz, Jonathan G. Zins, Feni K. Kadakia, Suzanne Smart, Jill A. Rafael-Fortney, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Jeovanna Lowe, Kyle T. Floyd, Subha V. Raman, Jessica A. Chadwick, Neha Rastogi, Paul M.L. Janssen, Sarah A. Swager
Publikováno v:
Journal of neuromuscular diseases. 3(3)
Background: Combined treatment with an angiotensin-converting enzyme inhibitor and a mineralocorticoid receptor (MR) antagonist improved cardiac and skeletal muscle function and pathology in a mouse model of Duchenne muscular dystrophy. MR is present