Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jonathan G, Lieber"'
Autor:
Michael B. Fessler, Jonathan G. Lieber, Samithamby Jeyaseelan, G. Scott Worthen, Jerry A. Nick, Scott K. Young, Patrick G. Arndt
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 171:606-615
A growing literature indicates that hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) modulate proinflammatory cellular signaling and functions. No studies to date, however, have addressed whether statins modulate pulmonary inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b85c98c795746edc8eee824604d3f3
https://doi.org/10.1164/rccm.200406-729oc
https://doi.org/10.1164/rccm.200406-729oc
Autor:
Kenneth C. Malcolm, Jonathan G. Lieber, Robert C. Murphy, G. Scott Worthen, S. Courtney Frasch, Christopher A. Johnson, Donna L. Bratton, Patrick G. Arndt, Jerry A. Nick, Michael B. Fessler
Publikováno v:
Journal of Biological Chemistry. 279:39989-39998
Lipid rafts are cholesterol-rich membrane microdomains that are thought to act as coordinated signaling platforms by regulating dynamic, agonist-induced translocation of signaling proteins. They have been described to play a role in multiple prototyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf64aa41af9679dfacfd70ee0ee0d1ab
https://doi.org/10.1074/jbc.m401080200
https://doi.org/10.1074/jbc.m401080200
Autor:
Kenneth C. Malcolm, Jose-Angel Gonzalo, Joseph M. Petty, G. Scott Worthen, Jerry A. Nick, Peter M. Henson, Scott K. Young, Benjamin T. Suratt, Jonathan G. Lieber
Publikováno v:
Blood. 104:565-571
The bone marrow is the primary site for neutrophil production and release into the circulation. Because the CXC chemokine receptor-4/stromal derived factor-1 (CXCR4/SDF-1) axis plays a central role in the interactions of hematopoietic stem cells, lym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9709cbadf400bb2740502500112ce6
https://doi.org/10.1182/blood-2003-10-3638
https://doi.org/10.1182/blood-2003-10-3638
Autor:
G. Scott Worthen, Benjamin T. Suratt, Gordon Keller, Saiphone Webb, Scott K. Young, Gary L. Johnson, Jonathan G. Lieber
Publikováno v:
Blood. 103:852-859
An embryonic stem (ES) cell/OP9 coculture system for the effective production of functional neutrophils is described. A 3-step differentiation strategy was developed that uses liquid culture, enabling reliable and abundant production of neutrophils a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0cd7caedba6772987562f636ca620b2
https://doi.org/10.1182/blood-2003-04-1030
https://doi.org/10.1182/blood-2003-04-1030
Autor:
Robert M. Evans, Jonathan G. Lieber
Publikováno v:
Journal of Cell Science. 109:3047-3058
During the differentiation of 3T3-L1 pre-adipocytes, vimentin intermediate filaments are reorganized to form cage-like structures around the nascent lipid droplets. Initial studies with 3T3-L1 cells indicated that aggregation of vimentin filaments by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f885f119da65ed247022f5e64f39a07
https://doi.org/10.1242/jcs.109.13.3047
https://doi.org/10.1242/jcs.109.13.3047
Publikováno v:
Journal of Cell Science. 107:1593-1607
Human SW-13 cells express the intermediate filament protein vimentin in a mosaic pattern (Hedberg, K. K. and Chen, L. B. (1986). Exp. Cell Res. 163, 509–517). We have isolated SW-13 clones that do (vim+) or do not (vim-) synthesize vimentin as anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1471bfd72c41fe14d3067db131fe2bce
https://doi.org/10.1242/jcs.107.6.1593
https://doi.org/10.1242/jcs.107.6.1593
Autor:
Michael B. Fessler, Jonathan G. Lieber, Jerry A. Nick, Kenneth C. Malcolm, Katie R. Poch, Milene T. Saavedra, Kerry L. Tomlin, Travis S. Walker, G. Scott Worthen, Michael L. Vasil
Cystic fibrosis (CF) lung disease features persistent neutrophil accumulation to the airways from the time of infancy. CF children are frequently exposed toPseudomonas aeruginosa, and by adulthood, 80% of CF patients are chronically infected. The for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ec0923a0d451bf97fdf245568941ec
https://europepmc.org/articles/PMC1111839/
https://europepmc.org/articles/PMC1111839/
Autor:
Jonathan G. Lieber, G. Scott Worthen, Jerry A. Nick, Michael B. Fessler, Scott K. Young, Patrick G. Arndt
Publikováno v:
American journal of respiratory and critical care medicine. 171(9)
The influx of neutrophils into the lung is a sentinel event in LPS-induced acute lung inflammation. Previous studies have shown that systemic inhibition of p38 decreases LPS-induced neutrophil influx into the alveolar space but has no effect on pulmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6f7e45f2936b9dfd1ceb537b9d2318
https://pubmed.ncbi.nlm.nih.gov/15735060
https://pubmed.ncbi.nlm.nih.gov/15735060
Publikováno v:
Methods in enzymology. 365
A reliable and effective in vitro differentiation system is described for the production of functional neutrophils from mouse embryonic stem (ES) cells. A three-step culture method was developed that enables abundant production and effective harvesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d97cef288ad6d81ece5c0d622869651d
https://pubmed.ncbi.nlm.nih.gov/14696342
https://pubmed.ncbi.nlm.nih.gov/14696342
A reliable and effective in vitro differentiation system is described for the production of functional neutrophils from mouse embryonic stem (ES) cells. A three-step culture method was developed that enables abundant production and effective harvesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57a386cd01090f7adc7cff5ebbda5764
https://doi.org/10.1016/s0076-6879(03)65009-3
https://doi.org/10.1016/s0076-6879(03)65009-3